Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.070 | GeneticVariation | BEFREE | The CAG haplotype (rs10821936, rs10994982, rs7089424) was strongly associated with ALL risk in our population (p < 0.00001). | 31227872 | 2019 |
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0.070 | GeneticVariation | BEFREE | ARID5B rs7089424 and rs10994982 might serve as genetic susceptibility markers for B-ALL in Chinese pediatric population. | 31274788 | 2019 |
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0.070 | GeneticVariation | BEFREE | However, the SNPs of <i>ARID5B</i> rs10821936 and rs10994982</span> were not found to be strongly associated with ALL outcomes. | 31424309 | 2019 |
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0.070 | GeneticVariation | BEFREE | These results indicate that SNPs rs10994982 and rs7089424 are indeed significantly associat</span>ed with increased risk of childhood ALL. | 25124600 | 2014 |
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0.070 | GeneticVariation | BEFREE | The SNPs (IKZF1 rs11978267, ARID5B rs10821936 and rs10994982, CEBPE rs2239633) were genotyped in 265 cases [169 acute lymphoblastic leukemia (ALL) and 96 acute myeloid leukaemia (AML)] and 505 controls by Taqman allelic discrimination assay. | 24564228 | 2014 |
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0.070 | GeneticVariation | BEFREE | In an attempt to replicate the findings of 2 recent genome-wide association studies in a French-Canadian cohort, we confirmed the association of 5 SNPs [rs7073837 (P=4.2 x 10(-4)), rs10994982 (P=3.8 x 10(-4)), rs10740055 (P=1.6 x 10(-5)), rs10821936 (P=1.7 x 10(-7)) and rs7089424 (P=3.6 x 10(-7))] in the ARID5B gene with childhood acute lymphoblastic leukemia. | 20460642 | 2010 |
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0.070 | GeneticVariation | BEFREE | Two SNPs in ARID5B not only differed between ALL and non-ALL groups (rs10821936, P = 1.4 x 10(-15), odds ratio (OR) = 1.91; rs10994982, P = 5.7 x 10(-9), OR = 1.62) but also distinguished B-hyperdiploid ALL from other subtypes (rs10821936, P = 1.62 x 10(-5), OR = 2.17; rs10994982, P = 0.003, OR 1.72). | 19684603 | 2009 |