| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
C | 0.710 | CausalMutation | CLINVAR | Prospective enterprise-level molecular genotyping of a cohort of cancer patients. | 25157968 | 2014 |
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|
C | 0.710 | CausalMutation | CLINVAR | The role of kinase inhibitors in the treatment of patients with acute myeloid leukemia. | 23714533 | 2013 |
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|
C | 0.710 | CausalMutation | CLINVAR | Mutational landscape of AML with normal cytogenetics: biological and clinical implications. | 23261068 | 2013 |
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|
C | 0.710 | CausalMutation | CLINVAR | Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia. | 23321257 | 2013 |
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|
C | 0.710 | CausalMutation | CLINVAR | The importance of relative mutant level for evaluating impact on outcome of KIT, FLT3 and CBL mutations in core-binding factor acute myeloid leukemia. | 23783394 | 2013 |
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|
C | 0.710 | CausalMutation | CLINVAR | Continuing aspirin in the perioperative patient. | 22504186 | 2012 |
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|
C | 0.710 | CausalMutation | CLINVAR | Sorafenib treatment of FLT3-ITD(+) acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation. | 22368270 | 2012 |
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|
C | 0.710 | CausalMutation | CLINVAR | [FMS-like tyrosine kinase 3 gene mutations in acute myeloid leukemia]. | 19840437 | 2009 |
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|
0.710 | GeneticVariation | BEFREE | Recently, novel mutations within the activation loop were identified in patients with AML: deletion of isoleucine 836 (Ile836del) and an exchange of isoleucine 836 to methionine plus an arginine insertion (Ile836Met+Arg). | 12663439 | 2003 |