Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913451
rs121913451
ABL1
G 0.710 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs121913451
rs121913451
ABL1
A 0.710 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs121913451
rs121913451
ABL1
G 0.710 GeneticVariation CLINVAR Detection of BCR-ABL kinase domain mutations in patients with chronic myeloid leukemia on imatinib. 23676790

2013
dbSNP: rs121913451
rs121913451
ABL1
A 0.710 GeneticVariation CLINVAR F317L BCR-ABL1 kinase domain mutation associated with a sustained major molecular response in a CML patient on dasatinib. 21489624

2011
dbSNP: rs121913451
rs121913451
ABL1
A 0.710 GeneticVariation CLINVAR BCR-ABL kinase domain mutation analysis in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors: recommendations from an expert panel on behalf of European LeukemiaNet. 21562040

2011
dbSNP: rs121913451
rs121913451
ABL1
G 0.710 GeneticVariation CLINVAR BCR-ABL kinase domain mutation analysis in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors: recommendations from an expert panel on behalf of European LeukemiaNet. 21562040

2011
dbSNP: rs121913451
rs121913451
ABL1
A 0.710 GeneticVariation CLINVAR Use of direct sequencing for detection of mutations in the BCR-ABL kinase domain in Slovak patients with chronic myeloid leukemia. 21895409

2011
dbSNP: rs121913451
rs121913451
ABL1
G 0.710 GeneticVariation CLINVAR Chronic myeloid leukemia patients with F317L BCR-ABL kinase domain mutation are resistant to dasatinib: is that true for all the patients? 21605905

2011
dbSNP: rs121913451
rs121913451
ABL1
G 0.710 GeneticVariation CLINVAR F317L BCR-ABL1 kinase domain mutation associated with a sustained major molecular response in a CML patient on dasatinib. 21489624

2011
dbSNP: rs121913451
rs121913451
ABL1
G 0.710 GeneticVariation CLINVAR Mutations in ABL kinase domain are associated with inferior progression-free survival. 20367437

2010
dbSNP: rs121913451
rs121913451
ABL1
A 0.710 GeneticVariation CLINVAR Mutations in ABL kinase domain are associated with inferior progression-free survival. 20367437

2010
dbSNP: rs121913451
rs121913451
ABL1
A 0.710 GeneticVariation CLINVAR P-loop mutations and novel therapeutic approaches for imatinib failures in chronic myeloid leukemia. 18828913

2008
dbSNP: rs121913451
rs121913451
ABL1
0.710 GeneticVariation BEFREE Characteristics and outcome of chronic myeloid leukemia patients with F317L BCR-ABL kinase domain mutation after therapy with tyrosine kinase inhibitors. 18818391

2008
dbSNP: rs121913451
rs121913451
ABL1
A 0.710 GeneticVariation CLINVAR Presence or the emergence of a F317L BCR-ABL mutation may be associated with resistance to dasatinib in Philadelphia chromosome-positive leukemia. 17114651

2006
dbSNP: rs121913451
rs121913451
ABL1
G 0.710 GeneticVariation CLINVAR Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis. 12623848

2003
dbSNP: rs121913451
rs121913451
ABL1
A 0.710 GeneticVariation CLINVAR Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis. 12623848

2003
dbSNP: rs121913451
rs121913451
ABL1
G 0.710 GeneticVariation CLINVAR High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance. 11964322

2002