A novel locus for FEV<sub>1</sub> identified among ever smokers (rs291231; P = 1.92 × 10<sup>-8</sup>) approached statistical significance for replication in admixed populations of African ancestry, and a novel SNP for COPD in PDZD2 (rs7709630; P = 1.56 × 10<sup>-8</sup>) regionally replicated.
A novel locus for FEV<sub>1</sub> identified among ever smokers (rs291231; P = 1.92 × 10<sup>-8</sup>) approached statistical significance for replication in admixed populations of African ancestry, and a novel SNP for COPD in PDZD2 (rs7709630; P = 1.56 × 10<sup>-8</sup>) regionally replicated.