Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11540652
rs11540652
TP53
T 0.720 GeneticVariation CLINVAR

dbSNP: rs121434629
rs121434629
PMS2
A 0.700 GeneticVariation CLINVAR

dbSNP: rs121918459
rs121918459
PTPN11
G 0.700 CausalMutation CLINVAR

dbSNP: rs267608150
rs267608150
PMS2
CTTCACACACA 0.700 CausalMutation CLINVAR

dbSNP: rs555607708
rs555607708
CHEK2
A 0.700 CausalMutation CLINVAR

dbSNP: rs63750250
rs63750250
PMS2
AT 0.700 CausalMutation CLINVAR

dbSNP: rs869312777
rs869312777
PTEN
G 0.700 GeneticVariation CLINVAR

dbSNP: rs1257715362
rs1257715362
MAPK10 ; ARHGAP24
0.010 GeneticVariation BEFREE PCR-SSCP and direct DNA sequencing of exons 2 to 14 of p73 revealed a missense mutation in one primary lymphoma: a G-to-A transition, with Glu291Lys change. 11461077

2001
dbSNP: rs1351687973
rs1351687973
TP73
0.010 GeneticVariation BEFREE PCR-SSCP and direct DNA sequencing of exons 2 to 14 of p73 revealed a missense mutation in one primary lymphoma: a G-to-A transition, with Glu291Lys change. 11461077

2001
dbSNP: rs1555525126
rs1555525126
TP53
0.010 GeneticVariation BEFREE PCR-SSCP and direct DNA sequencing of exons 2 to 14 of p73 revealed a missense mutation in one primary lymphoma: a G-to-A transition, with Glu291Lys change. 11461077

2001
dbSNP: rs535311760
rs535311760
TP73
0.010 GeneticVariation BEFREE PCR-SSCP and direct DNA sequencing of exons 2 to 14 of p73 revealed a missense mutation in one primary lymphoma: a G-to-A transition, with Glu291Lys change. 11461077

2001
dbSNP: rs397507444
rs397507444
MTHFR
0.050 GeneticVariation BEFREE C677T and A1298C methylenetetrahydrofolate reductase (MTHFR) polymorphisms have been suggested to affect susceptibility to malignant lymphoma, possibly by altering DNA methylation. 14535593

2004
dbSNP: rs1217691063
rs1217691063
MTHFR
0.030 GeneticVariation BEFREE C677T and A1298C methylenetetrahydrofolate reductase (MTHFR) polymorphisms have been suggested to affect susceptibility to malignant lymphoma, possibly by altering DNA methylation. 14535593

2004
dbSNP: rs773919809
rs773919809
MGMT
0.010 GeneticVariation BEFREE C677T and A1298C methylenetetrahydrofolate reductase (MTHFR) polymorphisms have been suggested to affect susceptibility to malignant lymphoma, possibly by altering DNA methylation. 14535593

2004
dbSNP: rs1802710
rs1802710
DLK1
0.010 GeneticVariation BEFREE Analysis of 47 brain tumors and 55 lymphomas found that 23 and 29 of them were heterozygous for rs1802710, respectively. 15010842

2004
dbSNP: rs25487
rs25487
XRCC1
0.020 GeneticVariation BEFREE Lack of association between DNA base excision repair gene XRCC1 Gln399Arg polymorphism and risk of malignant lymphoma in Japan. 15104288

2004
dbSNP: rs397507444
rs397507444
MTHFR
0.050 GeneticVariation BEFREE We have previously reported associations between lymphoma risk and germline polymorphisms in genes of methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) and methionine synthase (MTR A2756G), finding the genotype other than the MTHFR 677CC/1298AA to confer a half-risk compared to the MTHFR 677CC/1298AA and a 3-fold higher risk with the MTR GG genotype than the AA/AG genotypes. 15551285

2004
dbSNP: rs1217691063
rs1217691063
MTHFR
0.030 GeneticVariation BEFREE We have previously reported associations between lymphoma risk and germline polymorphisms in genes of methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) and methionine synthase (MTR A2756G), finding the genotype other than the MTHFR 677CC/1298AA to confer a half-risk compared to the MTHFR 677CC/1298AA and a 3-fold higher risk with the MTR GG genotype than the AA/AG genotypes. 15551285

2004
dbSNP: rs1805087
rs1805087
MTR
0.030 GeneticVariation BEFREE We have previously reported associations between lymphoma risk and germline polymorphisms in genes of methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) and methionine synthase (MTR A2756G), finding the genotype other than the MTHFR 677CC/1298AA to confer a half-risk compared to the MTHFR 677CC/1298AA and a 3-fold higher risk with the MTR GG genotype than the AA/AG genotypes. 15551285

2004
dbSNP: rs77375493
rs77375493
JAK2 ; INSL6
0.010 GeneticVariation BEFREE Interestingly, one of the patients with SM and the patient with CNL with JAK2 V617F had a history of lymphoma, and this patient with SM also had associated myelofibrosis and CMML. 15860661

2005
dbSNP: rs1346044
rs1346044
WRN
0.010 GeneticVariation BEFREE WRN Cys1367Arg was associated with decreased risk of NHL overall (OR: 0.71; 95% CI: 0.56-0.91; P=0.007) and DLBCL (OR: 0.66; 95% CI: 0.45-0.95; P=0.024), as well as follicular and marginal zone lymphomas. 16738949

2006
dbSNP: rs397507444
rs397507444
MTHFR
0.050 GeneticVariation BEFREE Recently, methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) mutations were discovered to be associated with childhood acute lymphoblastic leukemia (ALL), as well as colon cancer, lymphoma, esophageal and stomach cancer. 16886608

2006
dbSNP: rs4880
rs4880
SOD2
0.010 GeneticVariation BEFREE Data from two population-based, case-control studies of lymphoma in the UK (700 cases and 915 controls) and USA (1593 cases and 2517 controls) were pooled to analyze polymorphisms in genes involved in the oxidative stress response (SOD2 Val16Ala, CAT C-262T and GPX1 Pro197Leu). 16956821

2006
dbSNP: rs995922697
rs995922697
GPX1
0.010 GeneticVariation BEFREE Data from two population-based, case-control studies of lymphoma in the UK (700 cases and 915 controls) and USA (1593 cases and 2517 controls) were pooled to analyze polymorphisms in genes involved in the oxidative stress response (SOD2 Val16Ala, CAT C-262T and GPX1 Pro197Leu). 16956821

2006
dbSNP: rs3135932
rs3135932
IL10RA
0.010 GeneticVariation BEFREE The IL10RA Ser138Gly variant was underrepresented among lymphoma cases (odds ratio (OR)=0.81, 95 per cent confidence interval (95% CI)=0.65-1.02), mainly owing to an inverse association with Hodgkin's lymphoma (HL). 16971956

2006