Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs707824
rs707824
T 0.810 GeneticVariation GWASCAT A SNP in a novel non-HLA region on 6p23 (rs707824, P(NHL) = 5.72×10(-7)) was suggestive of an association conferring susceptibility to lymphoma. 23349640

2013

dbSNP: rs707824
rs707824
0.810 GeneticVariation BEFREE A SNP in a novel non-HLA region on 6p23 (rs707824, P(NHL) = 5.72×10(-7)) was suggestive of an association conferring susceptibility to lymphoma. 23349640

2013

dbSNP: rs707824
rs707824
T 0.810 GeneticVariation GWASDB A SNP in a novel non-HLA region on 6p23 (rs707824, P(NHL) = 5.72×10(-7)) was suggestive of an association conferring susceptibility to lymphoma. 23349640

2013

dbSNP: rs12289961
rs12289961
T 0.800 GeneticVariation GWASDB Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies. 23349640

2013

dbSNP: rs12289961
rs12289961
T 0.800 GeneticVariation GWASCAT Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies. 23349640

2013

dbSNP: rs2621416
rs2621416
G 0.800 GeneticVariation GWASDB Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies. 23349640

2013

dbSNP: rs2621416
rs2621416
G 0.800 GeneticVariation GWASCAT Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies. 23349640

2013

dbSNP: rs2647045
rs2647045
0.800 GeneticVariation GWASDB Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies. 23349640

2013

dbSNP: rs2647045
rs2647045
0.800 GeneticVariation GWASCAT Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies. 23349640

2013

dbSNP: rs4530903
rs4530903
T 0.800 GeneticVariation GWASDB Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies. 23349640

2013

dbSNP: rs4530903
rs4530903
T 0.800 GeneticVariation GWASCAT Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies. 23349640

2013

dbSNP: rs6773854
rs6773854
C 0.800 GeneticVariation GWASDB Genome-wide association study of B cell non-Hodgkin lymphoma identifies 3q27 as a susceptibility locus in the Chinese population. 23749188

2013

dbSNP: rs6773854
rs6773854
C 0.800 GeneticVariation GWASCAT Genome-wide association study of B cell non-Hodgkin lymphoma identifies 3q27 as a susceptibility locus in the Chinese population. 23749188

2013

dbSNP: rs9268853
rs9268853
C 0.800 GeneticVariation GWASCAT Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies. 23349640

2013

dbSNP: rs9268853
rs9268853
C 0.800 GeneticVariation GWASDB Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies. 23349640

2013

dbSNP: rs948562
rs948562
G 0.800 GeneticVariation GWASDB Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies. 23349640

2013

dbSNP: rs948562
rs948562
G 0.800 GeneticVariation GWASCAT Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies. 23349640

2013

dbSNP: rs11540652
rs11540652
0.720 GeneticVariation BEFREE We previously showed that the HSP90 inhibitor ganetespib potently suppresses T-lymphoma initiation and progression and extends overall survival (OS) in hotspot knockin mice expressing the p53 gain-of-function mutants R175H and R248Q (mutp53) by 30-59%. 28300840

2017

dbSNP: rs267601394
rs267601394
0.720 GeneticVariation BEFREE These results suggest that Ezh2(Y641F) induces lymphoma and melanoma through a vast reorganization of chromatin structure, inducing both repression and activation of polycomb-regulated loci. 27135738

2016

dbSNP: rs267601394
rs267601394
A 0.720 GeneticVariation CLINVAR Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma. 24563539

2014

dbSNP: rs267601394
rs267601394
0.720 GeneticVariation BEFREE As EZH2 mutations often coincide with other mutations in lymphoma, we combined the expression of EZH2(Y641F) by crossing these transgenic mice with Eµ-Myc transgenic mice. 24802772

2014

dbSNP: rs11540652
rs11540652
0.720 GeneticVariation BEFREE This was associated with a twofold higher T-lymphoma proliferation in R248Q/- mice compared with G245S/- and null mice. 23538418

2013

dbSNP: rs267601394
rs267601394
G 0.720 GeneticVariation CLINVAR A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells. 23023262

2012

dbSNP: rs267601394
rs267601394
A 0.720 GeneticVariation CLINVAR A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells. 23023262

2012

dbSNP: rs11540652
rs11540652
T 0.720 GeneticVariation CLINVAR