|
rs587776632
|
|
GAA |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs587776633
|
|
CT |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs587776634
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs587776635
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs587776636
|
|
GA |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs587776637
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs854560
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The numbers of cases of particular subtypes were rather small for stable estimates, but we noted that the PON1 L55M AA allele, associated with slightly increased risk of non-Hodgkin's lymphoma (variant homozygotes OR, 1.36; 95% CI, 0.96-1.95), was most strongly associated with follicular non-Hodgkin's lymphoma and T-cell lymphoma, with ORs for variant homozygotes of 2.12 and 2.93, respectively.
|
16985026 |
2006 |
|
rs1695
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We studied deletions of GSTM1 and GSTT1, and the GSTP1 Ile(105)Val polymorphism in 89 patients with follicular lymphoma (FL).
|
17454600 |
2007 |
|
rs587781386
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Double transversion mutations comprising of a missense mutation at codon 167 (Gln to His) in exon 5 and a nonsense mutation at codon 183 (Ser to stop codon) in exon 5 were detected in one DLBL that had apparently transformed from follicular lymphoma and in one advanced adult T-cell lymphoma (ATL).
|
17609875 |
2007 |
|
rs764562217
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Double transversion mutations comprising of a missense mutation at codon 167 (Gln to His) in exon 5 and a nonsense mutation at codon 183 (Ser to stop codon) in exon 5 were detected in one DLBL that had apparently transformed from follicular lymphoma and in one advanced adult T-cell lymphoma (ATL).
|
17609875 |
2007 |
|
rs3020314
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Four ESR1 SNPs were associated with follicular lymphoma (FL) in the U.S. study, with rs3020314 remaining associated with reduced risk of FL after multiple testing adjustments [odds ratio (OR) = 0.42, 95% confidence interval (CI) = 0.23-0.77) and replication in the German study (OR = 0.24, 95% CI = 0.06-0.94).
|
18636124 |
2008 |
|
rs172378
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotyping for C1qA([276A/G]) was done in 133 subjects with follicular lymphoma treated with single-agent rituximab, and correlation with clinical response was done using Cox regression analysis.
|
18927313 |
2008 |
|
rs372411058
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotyping for C1qA([276A/G]) was done in 133 subjects with follicular lymphoma treated with single-agent rituximab, and correlation with clinical response was done using Cox regression analysis.
|
18927313 |
2008 |
|
rs3789068
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Variants in BCL2L11 were strongly related to follicular lymphoma only, particularly rs3789068 (OR(AG), 1.41; 95% CI, 1.10-1.81; OR(GG), 1.65; 95% CI, 1.25-2.19; P(trend) = 0.0004).
|
19336552 |
2009 |
|
rs10190751
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A comparison of 183 patients with follicular lymphoma and 233 population controls revealed an increased lymphoma risk associated with the rs10190751 A genotype causing c-FLIP(R) expression.
|
19439735 |
2009 |
|
rs6457327
|
|
|
0.750 |
GeneticVariation |
BEFREE |
We found that rs6457327 on 6p21.33 was associated with susceptibility to follicular lymphoma (FL; N = 189 cases, 592 controls) with validation in another 456 FL cases and 2,785 controls (combined allelic P = 4.7 x 10(-11)).
|
19620980 |
2009 |
|
rs6457327
|
|
C |
0.750 |
GeneticVariation |
GWASDB |
We found that rs6457327 on 6p21.33 was associated with susceptibility to follicular lymphoma (FL; N = 189 cases, 592 controls) with validation in another 456 FL cases and 2,785 controls (combined allelic P = 4.7 x 10(-11)).
|
19620980 |
2009 |
|
rs1308699981
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we analyzed the FcgammaRIIIa 158 V/F, FcgammaRIIa 131 H/R, and FcgammaRIIb 232 I/T polymorphisms in a group of 188 patients with follicular lymphoma who were treated with chemotherapy without rituximab initially.
|
19672774 |
2009 |
|
rs1217691063
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We studied the association between the different genotypes of the two most common MTHFR polymorphisms, C677T and A1298C, and the risk of follicular lymphoma (FL).
|
19963111 |
2009 |
|
rs397507444
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The frequency of the A1298C CC homozygous mutant genotype was significantly higher in patients with FL than in control subjects (OR = 3.51, 95% CI = 1.39-8.86, P = 0.008).
|
19963111 |
2009 |
|
rs2228479
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The variant allele at V92M was associated with FL (odds ratio (OR)=1.61, 95% confidence interval (CI) 1.08-2.39) and the r:wild type genotype with DLBCL (OR=0.58, 95% CI 0.38-0.89).
|
20129839 |
2010 |
|
rs1883832
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Data from earlier studies that are part of this pooling study implicate a functional polymorphism (-1C>T, rs1883832) in the TNFRSF5 gene encoding CD40 in the etiology of follicular lymphoma.
|
20473910 |
2011 |
|
rs10484561
|
|
G |
0.770 |
GeneticVariation |
GWASDB |
We identified two variants associated with follicular lymphoma at 6p21.32 (rs10484561, combined P = 1.12 x 10(-29) and rs7755224, combined P = 2.00 x 10(-19); r(2) = 1.0), supporting the idea that major histocompatibility complex genetic variation influences follicular lymphoma susceptibility.
|
20639881 |
2010 |
|
rs10484561
|
|
|
0.770 |
GeneticVariation |
BEFREE |
We identified two variants associated with follicular lymphoma at 6p21.32 (rs10484561, combined P = 1.12 x 10(-29) and rs7755224, combined P = 2.00 x 10(-19); r(2) = 1.0), supporting the idea that major histocompatibility complex genetic variation influences follicular lymphoma susceptibility.
|
20639881 |
2010 |
|
rs735665
|
|
T |
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32.
|
20639881 |
2010 |