|
rs397507444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
C677T and A1298C polymorphisms of methylene tetrahydrofolate reductase in non-Hodgkin lymphoma: southeast Iran.
|
28430351 |
2018 |
|
rs397507444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Two common polymorphisms, the c. 677C > T and c. 1298A > C, of the methylene-tetrahydrofolate reductase (MTHFR) gene, an enzyme essential in DNA synthesis and methylation, have been associated with susceptibility to NHL.
|
28779180 |
2017 |
|
rs397507444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Increased NHL risk was also shown for A1298C among Asians.
|
25146845 |
2014 |
|
rs397507444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In the Indians however, the MTHFR A1298C confers risk to NHL.
|
24646728 |
2014 |
|
rs397507444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate the genetic polymorphisms in 5, 10-methylenetetrahydrofolate reductase (MTHFR 677C/T and 1298A/C) and to evaluate its associations with the risk of Non Hodgkin lymphoma.
|
23174714 |
2013 |
|
rs397507444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The aim of our study was to investigate the potential influence of the C677T and A1298C genetic variants of the methylenetetrahydrofolate reductase (MTHFR) gene on the clinical toxicity and efficacy of MTX in pediatric patients with NHL (n = 95) treated with therapeutic protocols Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) LNH-97 and EURO LB-02.
|
23488607 |
2013 |
|
rs397507444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms and therapy-related toxicity in children treated for acute lymphoblastic leukemia and non-Hodgkin lymphoma.
|
19391036 |
2009 |
|
rs397507444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This is the first reported case of intracardiac thrombosis with MTHFR A1298C and factor XIII V34L mutations together with granulomatous reaction in non-Hodgkin lymphoma.
|
18432505 |
2008 |
|
rs397507444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In a case-control study, we evaluated whether four common polymorphisms in methylenetetrahydrofolate reductase (MTHFR C677T and A1298C), methionine synthase (MS A2756G), and methionine synthase reductase (MTRR A66G) genes may have a role in altering susceptibility to adult acute lymphoblastic leukemia (ALL) and non-Hodgkin's lymphoma (NHL).
|
15159311 |
2004 |
|
rs397507444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The polymorphisms examined and haplotypes generated included thymidylate synthase (TYMS 28-bp triple repeat [3R]-->double repeat [2R], 1494del6, IVS6 -68C>T, 1122A>G, and 1053C>T); 5,10-methylenetetrahydrofolate reductase (MTHFR 677C>T and 1298A>C); serine hydroxymethyltransferase (SHMT1 C1420T); reduced folate carrier (RFC G80A); and methionine synthase (MTR A2756G), making the present study the largest and most comprehensive to date to evaluate associations between genetic polymorphisms in folatemetabolizing genes and NHL risk.
|
15198953 |
2004 |
|
rs397507444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We analysed genetic polymorphisms for methionine synthase (MS) A2756G, methylenetetrahydrofolate reductase (MTHFR) C677T and MTHFR A1298C in Caucasians with non-Hodgkin's lymphoma (NHL; n = 151), multiple myeloma (MM; n = 90) and 299 control subjects.
|
12648076 |
2003 |