Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2758339
rs2758339
0.010 GeneticVariation BEFREE This study indicates that the SOD2 polymorphism (rs2758339, rs5746136) is associated with increased risk of gastric cancer, especially in smoker individuals. 30242560

2020

dbSNP: rs5746136
rs5746136
0.010 GeneticVariation BEFREE This study indicates that the SOD2 polymorphism (rs2758339, rs5746136) is associated with increased risk of gastric cancer, especially in smoker individuals. 30242560

2020

dbSNP: rs8193
rs8193
0.010 GeneticVariation BEFREE rs8193 is statistically associated with the risk of malignancy, lymph node spread and stage of gastric cancer in Iranian population. 31376327

2020

dbSNP: rs1016343
rs1016343
0.010 GeneticVariation BEFREE In the stratification analyses, the recessive model indicated that the rs1016343 TT genotype was significantly associated with decreased GC risk in individuals aged <60 years showing lymph node metastasis (LNM)-negative results. 31288430

2019

dbSNP: rs1044432
rs1044432
0.010 GeneticVariation BEFREE Among the nine SNPs, rs11133399 in CLOCK, rs1044432 and rs2279284 in BAML1 were significantly associated with GC overall survival and recurrence-free survival. 30843665

2019

dbSNP: rs10509670
rs10509670
0.010 GeneticVariation BEFREE Results showed that the minor alleles of rs3765524, rs2274223, and rs10509670 were associated with increased risk of EC and GC. 30931333

2019

dbSNP: rs1057519847
rs1057519847
0.010 GeneticVariation BEFREE We detected the epidermal growth factor receptor L858R, MSH2 R929* and telomerase reverse transcriptase amplification in the lung cancer specimen; CDH1 c.1320+1G>T mutation in the gastric cancer (GC) specimen; and MLH1 c.1896+5G>A germline mutation in the lung and GC specimens by 450 cancer-related gene mutations detection using next-generation sequencing technology. 31207149

2019

dbSNP: rs1057519848
rs1057519848
0.010 GeneticVariation BEFREE We detected the epidermal growth factor receptor L858R, MSH2 R929* and telomerase reverse transcriptase amplification in the lung cancer specimen; CDH1 c.1320+1G>T mutation in the gastric cancer (GC) specimen; and MLH1 c.1896+5G>A germline mutation in the lung and GC specimens by 450 cancer-related gene mutations detection using next-generation sequencing technology. 31207149

2019

dbSNP: rs1058808
rs1058808
0.010 GeneticVariation BEFREE Increased risk for GC was observed under the dominant inheritance model for the rs2643194 TT or CT genotypes with an OR of 2.75 (95%CI 1.12-6.75, P=0.023); the rs2934971 TT or GT genotypes with an OR of 2.41 (95%CI 1.01-5.76, P=0.043), and the rs1058808 GG or CG genotypes with an OR of 2.21 (95%CI 1.00-4.87, P=0.046). 31116314

2019

dbSNP: rs11084490
rs11084490
0.010 GeneticVariation BEFREE Our results revealed that AURKA (rs1047972 and rs911160), AURKB (rs2241909 and rs2289590) and AURKC (rs11084490) are associated with a higher risk of GC susceptibility. 31521144

2019

dbSNP: rs11133399
rs11133399
0.010 GeneticVariation BEFREE Immunohistochemical analysis further demonstrated that the genotype of rs11133399 was significantly associated with the expression level of CLOCK in GC tissues, suggesting that this SNP might affect the prognosis of GC through its influence on the expression of CLOCK gene. 30843665

2019

dbSNP: rs1126757
rs1126757
0.010 GeneticVariation BEFREE We found that rs1126760 (C vs T: OR=1.39, 95% CIs=1.13-1.70, <i>P</i>=0.002) and rs1126757 (C vs T: OR=0.82, 95% CIs=0.72-0.93, <i>P</i>=0.002) were significantly associated with susceptibility of GC. 31686851

2019

dbSNP: rs1126760
rs1126760
0.010 GeneticVariation BEFREE We found that rs1126760 (C vs T: OR=1.39, 95% CIs=1.13-1.70, <i>P</i>=0.002) and rs1126757 (C vs T: OR=0.82, 95% CIs=0.72-0.93, <i>P</i>=0.002) were significantly associated with susceptibility of GC. 31686851

2019

dbSNP: rs11655237
rs11655237
0.010 GeneticVariation BEFREE <b>Conclusion:</b> Our results indicate that LINC00673 rs11655237 is associated with an increased GC risk, possibly by down-regulating LINC00673 expression through creating a miR-1231 binding site. 31118802

2019

dbSNP: rs121434568
rs121434568
0.010 GeneticVariation BEFREE We detected the epidermal growth factor receptor L858R, MSH2 R929* and telomerase reverse transcriptase amplification in the lung cancer specimen; CDH1 c.1320+1G>T mutation in the gastric cancer (GC) specimen; and MLH1 c.1896+5G>A germline mutation in the lung and GC specimens by 450 cancer-related gene mutations detection using next-generation sequencing technology. 31207149

2019

dbSNP: rs12416605
rs12416605
0.010 GeneticVariation BEFREE rs12416605:C>T in MIR938 associates with gastric cancer through affecting the regulation of the CXCL12 chemokine gene. 31273931

2019

dbSNP: rs13252298
rs13252298
0.010 GeneticVariation BEFREE The rs13252298 GG genotype in the recessive model showed increased GC risk in subjects aged ≥60 years showing LNM-positive results and those aged ≥60 years in tumor stage III. 31288430

2019

dbSNP: rs144779807
rs144779807
0.010 GeneticVariation BEFREE We detected the epidermal growth factor receptor L858R, MSH2 R929* and telomerase reverse transcriptase amplification in the lung cancer specimen; CDH1 c.1320+1G>T mutation in the gastric cancer (GC) specimen; and MLH1 c.1896+5G>A germline mutation in the lung and GC specimens by 450 cancer-related gene mutations detection using next-generation sequencing technology. 31207149

2019

dbSNP: rs1532268
rs1532268
0.010 GeneticVariation BEFREE In the allele model, using the chi-square test, we found that the rs1532268 in MTRR with a minor allele T was significantly associated with increased risk of GC (OR = 1.24, 95% CI, 1.00-1.53; p = 0.048). 30884202

2019

dbSNP: rs1760944
rs1760944
0.010 GeneticVariation BEFREE Nine variants on nine genes were rated as presenting strong cumulative epidemiological evidence for a nominally significant association with GC risk, including <i>APE1</i> (rs1760944), <i>DNMT1</i> (rs16999593), <i>ERCC5</i> (rs751402), <i>GSTT1</i> (null/presence), <i>MDM2</i> (rs2278744), <i>PPARG</i> (rs1801282), <i>TLR4</i> (rs4986790), <i>IL-17F</i> (rs763780), and <i>CASP8</i> (rs3834129). 31516756

2019

dbSNP: rs1800469
rs1800469
0.010 GeneticVariation BEFREE SNPs in TGFβ (- 509 C/T, rs1800469) and IL-10 (- 819 C/T, rs1800871) promoters were associated with a lower risk for GC in a Mexican population. 31092242

2019

dbSNP: rs1800625
rs1800625
0.010 GeneticVariation BEFREE <b>Conclusions:</b><i>RAGE</i> gene SNP rs1800625 was significantly associated with gastric cancer risk, and rs1800625 and rs184003 were related to tumor clinical stage, indicating that <i>RAGE</i> gene may be a gastric cancer-susceptibility gene. 30719146

2019

dbSNP: rs1870377
rs1870377
KDR
0.010 GeneticVariation BEFREE Our study suggested that the high expression of VEGFR-2, as well as the VEGFR-2 rs1870377 A > T genetic polymorphism, may be prognostic markers for GC. 30380970

2019

dbSNP: rs199971565
rs199971565
0.010 GeneticVariation BEFREE In conclusion, for the first time, this study indicated the association and in silico investigations of rs199971565 and suggested it as a novel INDEL biomarker located in the seed site of miR-302c, which may have crucial roles in the susceptibility to GC and its incidence risk. 31219213

2019

dbSNP: rs20417
rs20417
0.010 GeneticVariation BEFREE This meta-analysis of 15 case-control studies provides strong evidence that the COX-2 rs20417 polymorphism increases the risk of GC susceptibility in general populations, especially in Asians. 31045826

2019