rs2758339
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study indicates that the SOD2 polymorphism (rs2758339, rs5746136) is associated with increased risk of gastric cancer, especially in smoker individuals.
|
30242560 |
2020 |
rs5746136
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study indicates that the SOD2 polymorphism (rs2758339, rs5746136) is associated with increased risk of gastric cancer, especially in smoker individuals.
|
30242560 |
2020 |
rs8193
|
|
|
0.010 |
GeneticVariation |
BEFREE |
rs8193 is statistically associated with the risk of malignancy, lymph node spread and stage of gastric cancer in Iranian population.
|
31376327 |
2020 |
rs1016343
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the stratification analyses, the recessive model indicated that the rs1016343 TT genotype was significantly associated with decreased GC risk in individuals aged <60 years showing lymph node metastasis (LNM)-negative results.
|
31288430 |
2019 |
rs1044432
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among the nine SNPs, rs11133399 in CLOCK, rs1044432 and rs2279284 in BAML1 were significantly associated with GC overall survival and recurrence-free survival.
|
30843665 |
2019 |
rs10509670
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Results showed that the minor alleles of rs3765524, rs2274223, and rs10509670 were associated with increased risk of EC and GC.
|
30931333 |
2019 |
rs1057519847
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We detected the epidermal growth factor receptor L858R, MSH2 R929* and telomerase reverse transcriptase amplification in the lung cancer specimen; CDH1 c.1320+1G>T mutation in the gastric cancer (GC) specimen; and MLH1 c.1896+5G>A germline mutation in the lung and GC specimens by 450 cancer-related gene mutations detection using next-generation sequencing technology.
|
31207149 |
2019 |
rs1057519848
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We detected the epidermal growth factor receptor L858R, MSH2 R929* and telomerase reverse transcriptase amplification in the lung cancer specimen; CDH1 c.1320+1G>T mutation in the gastric cancer (GC) specimen; and MLH1 c.1896+5G>A germline mutation in the lung and GC specimens by 450 cancer-related gene mutations detection using next-generation sequencing technology.
|
31207149 |
2019 |
rs1058808
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Increased risk for GC was observed under the dominant inheritance model for the rs2643194 TT or CT genotypes with an OR of 2.75 (95%CI 1.12-6.75, P=0.023); the rs2934971 TT or GT genotypes with an OR of 2.41 (95%CI 1.01-5.76, P=0.043), and the rs1058808 GG or CG genotypes with an OR of 2.21 (95%CI 1.00-4.87, P=0.046).
|
31116314 |
2019 |
rs11084490
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results revealed that AURKA (rs1047972 and rs911160), AURKB (rs2241909 and rs2289590) and AURKC (rs11084490) are associated with a higher risk of GC susceptibility.
|
31521144 |
2019 |
rs11133399
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Immunohistochemical analysis further demonstrated that the genotype of rs11133399 was significantly associated with the expression level of CLOCK in GC tissues, suggesting that this SNP might affect the prognosis of GC through its influence on the expression of CLOCK gene.
|
30843665 |
2019 |
rs1126757
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that rs1126760 (C vs T: OR=1.39, 95% CIs=1.13-1.70, <i>P</i>=0.002) and rs1126757 (C vs T: OR=0.82, 95% CIs=0.72-0.93, <i>P</i>=0.002) were significantly associated with susceptibility of GC.
|
31686851 |
2019 |
rs1126760
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that rs1126760 (C vs T: OR=1.39, 95% CIs=1.13-1.70, <i>P</i>=0.002) and rs1126757 (C vs T: OR=0.82, 95% CIs=0.72-0.93, <i>P</i>=0.002) were significantly associated with susceptibility of GC.
|
31686851 |
2019 |
rs11655237
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Conclusion:</b> Our results indicate that LINC00673 rs11655237 is associated with an increased GC risk, possibly by down-regulating LINC00673 expression through creating a miR-1231 binding site.
|
31118802 |
2019 |
rs121434568
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We detected the epidermal growth factor receptor L858R, MSH2 R929* and telomerase reverse transcriptase amplification in the lung cancer specimen; CDH1 c.1320+1G>T mutation in the gastric cancer (GC) specimen; and MLH1 c.1896+5G>A germline mutation in the lung and GC specimens by 450 cancer-related gene mutations detection using next-generation sequencing technology.
|
31207149 |
2019 |
rs12416605
|
|
|
0.010 |
GeneticVariation |
BEFREE |
rs12416605:C>T in MIR938 associates with gastric cancer through affecting the regulation of the CXCL12 chemokine gene.
|
31273931 |
2019 |
rs13252298
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs13252298 GG genotype in the recessive model showed increased GC risk in subjects aged ≥60 years showing LNM-positive results and those aged ≥60 years in tumor stage III.
|
31288430 |
2019 |
rs144779807
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We detected the epidermal growth factor receptor L858R, MSH2 R929* and telomerase reverse transcriptase amplification in the lung cancer specimen; CDH1 c.1320+1G>T mutation in the gastric cancer (GC) specimen; and MLH1 c.1896+5G>A germline mutation in the lung and GC specimens by 450 cancer-related gene mutations detection using next-generation sequencing technology.
|
31207149 |
2019 |
rs1532268
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the allele model, using the chi-square test, we found that the rs1532268 in MTRR with a minor allele T was significantly associated with increased risk of GC (OR = 1.24, 95% CI, 1.00-1.53; p = 0.048).
|
30884202 |
2019 |
rs1760944
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Nine variants on nine genes were rated as presenting strong cumulative epidemiological evidence for a nominally significant association with GC risk, including <i>APE1</i> (rs1760944), <i>DNMT1</i> (rs16999593), <i>ERCC5</i> (rs751402), <i>GSTT1</i> (null/presence), <i>MDM2</i> (rs2278744), <i>PPARG</i> (rs1801282), <i>TLR4</i> (rs4986790), <i>IL-17F</i> (rs763780), and <i>CASP8</i> (rs3834129).
|
31516756 |
2019 |
rs1800469
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNPs in TGFβ (- 509 C/T, rs1800469) and IL-10 (- 819 C/T, rs1800871) promoters were associated with a lower risk for GC in a Mexican population.
|
31092242 |
2019 |
rs1800625
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Conclusions:</b><i>RAGE</i> gene SNP rs1800625 was significantly associated with gastric cancer risk, and rs1800625 and rs184003 were related to tumor clinical stage, indicating that <i>RAGE</i> gene may be a gastric cancer-susceptibility gene.
|
30719146 |
2019 |
rs1870377
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our study suggested that the high expression of VEGFR-2, as well as the VEGFR-2 rs1870377 A > T genetic polymorphism, may be prognostic markers for GC.
|
30380970 |
2019 |
rs199971565
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, for the first time, this study indicated the association and in silico investigations of rs199971565 and suggested it as a novel INDEL biomarker located in the seed site of miR-302c, which may have crucial roles in the susceptibility to GC and its incidence risk.
|
31219213 |
2019 |
rs20417
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This meta-analysis of 15 case-control studies provides strong evidence that the COX-2 rs20417 polymorphism increases the risk of GC susceptibility in general populations, especially in Asians.
|
31045826 |
2019 |