Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2294008
rs2294008
PSCA ; JRK
0.100 GeneticVariation BEFREE Many epidemiological studies have identified the PSCA rs2294008 T-allele as a risk factor of GC, while others have found an association between the rs2294008 C-allele and risk of DU and gastric ulcer (GU). 31839644

2019

dbSNP: rs2274223
rs2274223
0.100 GeneticVariation BEFREE Collectively, this meta-analysis demonstrated that <i>CTLA-4</i> rs5742909 and <i>PLCE1</i> rs2274223 polymorphisms may confer susceptibility to GC, especially for East Asians. 31767616

2019

dbSNP: rs5742909
rs5742909
0.010 GeneticVariation BEFREE Collectively, this meta-analysis demonstrated that <i>CTLA-4</i> rs5742909 and <i>PLCE1</i> rs2274223 polymorphisms may confer susceptibility to GC, especially for East Asians. 31767616

2019

dbSNP: rs920778
rs920778
0.040 GeneticVariation BEFREE A single nucleotide polymorphism (SNP) rs920778 in the HOTAIR gene, has been recurrently studied for susceptibility to many cancers including oesophageal cancer, gastric cancer, lung cancer, and hepatocellular carcinoma. 31759985

2020

dbSNP: rs1126757
rs1126757
0.010 GeneticVariation BEFREE We found that rs1126760 (C vs T: OR=1.39, 95% CIs=1.13-1.70, <i>P</i>=0.002) and rs1126757 (C vs T: OR=0.82, 95% CIs=0.72-0.93, <i>P</i>=0.002) were significantly associated with susceptibility of GC. 31686851

2019

dbSNP: rs1126760
rs1126760
0.010 GeneticVariation BEFREE We found that rs1126760 (C vs T: OR=1.39, 95% CIs=1.13-1.70, <i>P</i>=0.002) and rs1126757 (C vs T: OR=0.82, 95% CIs=0.72-0.93, <i>P</i>=0.002) were significantly associated with susceptibility of GC. 31686851

2019

dbSNP: rs889312
rs889312
0.020 GeneticVariation BEFREE Cox regression analysis, log-rank test and Kaplan-Meier method were used to explore the link between MAP3K1 rs889312 variant and overall survival (OS) of GC. 31686841

2019

dbSNP: rs2094258
rs2094258
0.060 GeneticVariation BEFREE The increase in C alleles of rs2094258 [hazard ratio (HR) = 1.19, 95% confidence interval (CI): 1.02-1.45, <i>P</i> = 0.037] were associated with the long-term survival of GC cases. 31558863

2019

dbSNP: rs2296147
rs2296147
0.030 GeneticVariation BEFREE None of the examined loci were statistically associated with GC risk, although rs2296147 was marginally associated with GC risk (<i>P</i> = 0.050). 31558863

2019

dbSNP: rs3737589
rs3737589
0.010 GeneticVariation BEFREE Our findings showed that the lncRNA <i>TP73-AS1</i> rs3737589 polymorphism might increase the risk of GC, and rs3737589 polymorphism could be a potential biomarker to predict the prognosis of GC patients. 31549851

2019

dbSNP: rs7515164
rs7515164
0.010 GeneticVariation BEFREE This study was to reveal the association between lncRNAs <i>TP73-AS1</i> polymorphisms (rs1181865 A > G, rs9800 G > C, rs3737589 A > G, rs2298222 G > A, rs7515164 C > A) and GC in 1000 GC cases and 1000 controls in a Chinese Han population. 31549851

2019

dbSNP: rs2228570
rs2228570
VDR
0.010 GeneticVariation BEFREE Our results indicate that VDR rs731236 & rs2228570 or VDBP rs7041 polymorphisms were not risk factors for the development of gastric cancer individually, however, lower serum levels of vitamin D may be a contributory risk for both predisposition and development of gastric cancer. 31549372

2019

dbSNP: rs7041
rs7041
GC
0.010 GeneticVariation BEFREE Our results indicate that VDR rs731236 & rs2228570 or VDBP rs7041 polymorphisms were not risk factors for the development of gastric cancer individually, however, lower serum levels of vitamin D may be a contributory risk for both predisposition and development of gastric cancer. 31549372

2019

dbSNP: rs731236
rs731236
VDR
0.010 GeneticVariation BEFREE Our results indicate that VDR rs731236 & rs2228570 or VDBP rs7041 polymorphisms were not risk factors for the development of gastric cancer individually, however, lower serum levels of vitamin D may be a contributory risk for both predisposition and development of gastric cancer. 31549372

2019

dbSNP: rs1047972
rs1047972
0.030 GeneticVariation BEFREE Our results revealed that AURKA (rs1047972 and rs911160), AURKB (rs2241909 and rs2289590) and AURKC (rs11084490) are associated with a higher risk of GC susceptibility. 31521144

2019

dbSNP: rs2241909
rs2241909
0.020 GeneticVariation BEFREE Our results revealed that AURKA (rs1047972 and rs911160), AURKB (rs2241909 and rs2289590) and AURKC (rs11084490) are associated with a higher risk of GC susceptibility. 31521144

2019

dbSNP: rs2289590
rs2289590
0.020 GeneticVariation BEFREE Our results revealed that AURKA (rs1047972 and rs911160), AURKB (rs2241909 and rs2289590) and AURKC (rs11084490) are associated with a higher risk of GC susceptibility. 31521144

2019

dbSNP: rs911160
rs911160
0.020 GeneticVariation BEFREE Our results revealed that AURKA (rs1047972 and rs911160), AURKB (rs2241909 and rs2289590) and AURKC (rs11084490) are associated with a higher risk of GC susceptibility. 31521144

2019

dbSNP: rs11084490
rs11084490
0.010 GeneticVariation BEFREE Our results revealed that AURKA (rs1047972 and rs911160), AURKB (rs2241909 and rs2289590) and AURKC (rs11084490) are associated with a higher risk of GC susceptibility. 31521144

2019

dbSNP: rs4986790
rs4986790
0.100 GeneticVariation BEFREE Nine variants on nine genes were rated as presenting strong cumulative epidemiological evidence for a nominally significant association with GC risk, including <i>APE1</i> (rs1760944), <i>DNMT1</i> (rs16999593), <i>ERCC5</i> (rs751402), <i>GSTT1</i> (null/presence), <i>MDM2</i> (rs2278744), <i>PPARG</i> (rs1801282), <i>TLR4</i> (rs4986790), <i>IL-17F</i> (rs763780), and <i>CASP8</i> (rs3834129). 31516756

2019

dbSNP: rs751402
rs751402
0.100 GeneticVariation BEFREE Nine variants on nine genes were rated as presenting strong cumulative epidemiological evidence for a nominally significant association with GC risk, including <i>APE1</i> (rs1760944), <i>DNMT1</i> (rs16999593), <i>ERCC5</i> (rs751402), <i>GSTT1</i> (null/presence), <i>MDM2</i> (rs2278744), <i>PPARG</i> (rs1801282), <i>TLR4</i> (rs4986790), <i>IL-17F</i> (rs763780), and <i>CASP8</i> (rs3834129). 31516756

2019

dbSNP: rs763780
rs763780
0.100 GeneticVariation BEFREE Nine variants on nine genes were rated as presenting strong cumulative epidemiological evidence for a nominally significant association with GC risk, including <i>APE1</i> (rs1760944), <i>DNMT1</i> (rs16999593), <i>ERCC5</i> (rs751402), <i>GSTT1</i> (null/presence), <i>MDM2</i> (rs2278744), <i>PPARG</i> (rs1801282), <i>TLR4</i> (rs4986790), <i>IL-17F</i> (rs763780), and <i>CASP8</i> (rs3834129). 31516756

2019

dbSNP: rs1801282
rs1801282
0.080 GeneticVariation BEFREE Nine variants on nine genes were rated as presenting strong cumulative epidemiological evidence for a nominally significant association with GC risk, including <i>APE1</i> (rs1760944), <i>DNMT1</i> (rs16999593), <i>ERCC5</i> (rs751402), <i>GSTT1</i> (null/presence), <i>MDM2</i> (rs2278744), <i>PPARG</i> (rs1801282), <i>TLR4</i> (rs4986790), <i>IL-17F</i> (rs763780), and <i>CASP8</i> (rs3834129). 31516756

2019

dbSNP: rs16999593
rs16999593
0.030 GeneticVariation BEFREE Nine variants on nine genes were rated as presenting strong cumulative epidemiological evidence for a nominally significant association with GC risk, including <i>APE1</i> (rs1760944), <i>DNMT1</i> (rs16999593), <i>ERCC5</i> (rs751402), <i>GSTT1</i> (null/presence), <i>MDM2</i> (rs2278744), <i>PPARG</i> (rs1801282), <i>TLR4</i> (rs4986790), <i>IL-17F</i> (rs763780), and <i>CASP8</i> (rs3834129). 31516756

2019

dbSNP: rs1760944
rs1760944
0.010 GeneticVariation BEFREE Nine variants on nine genes were rated as presenting strong cumulative epidemiological evidence for a nominally significant association with GC risk, including <i>APE1</i> (rs1760944), <i>DNMT1</i> (rs16999593), <i>ERCC5</i> (rs751402), <i>GSTT1</i> (null/presence), <i>MDM2</i> (rs2278744), <i>PPARG</i> (rs1801282), <i>TLR4</i> (rs4986790), <i>IL-17F</i> (rs763780), and <i>CASP8</i> (rs3834129). 31516756

2019