rs2294008
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Many epidemiological studies have identified the PSCA rs2294008 T-allele as a risk factor of GC, while others have found an association between the rs2294008 C-allele and risk of DU and gastric ulcer (GU).
|
31839644 |
2019 |
rs2274223
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Collectively, this meta-analysis demonstrated that <i>CTLA-4</i> rs5742909 and <i>PLCE1</i> rs2274223 polymorphisms may confer susceptibility to GC, especially for East Asians.
|
31767616 |
2019 |
rs5742909
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Collectively, this meta-analysis demonstrated that <i>CTLA-4</i> rs5742909 and <i>PLCE1</i> rs2274223 polymorphisms may confer susceptibility to GC, especially for East Asians.
|
31767616 |
2019 |
rs920778
|
|
|
0.040 |
GeneticVariation |
BEFREE |
A single nucleotide polymorphism (SNP) rs920778 in the HOTAIR gene, has been recurrently studied for susceptibility to many cancers including oesophageal cancer, gastric cancer, lung cancer, and hepatocellular carcinoma.
|
31759985 |
2020 |
rs1126757
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that rs1126760 (C vs T: OR=1.39, 95% CIs=1.13-1.70, <i>P</i>=0.002) and rs1126757 (C vs T: OR=0.82, 95% CIs=0.72-0.93, <i>P</i>=0.002) were significantly associated with susceptibility of GC.
|
31686851 |
2019 |
rs1126760
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that rs1126760 (C vs T: OR=1.39, 95% CIs=1.13-1.70, <i>P</i>=0.002) and rs1126757 (C vs T: OR=0.82, 95% CIs=0.72-0.93, <i>P</i>=0.002) were significantly associated with susceptibility of GC.
|
31686851 |
2019 |
rs889312
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Cox regression analysis, log-rank test and Kaplan-Meier method were used to explore the link between MAP3K1 rs889312 variant and overall survival (OS) of GC.
|
31686841 |
2019 |
rs2094258
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The increase in C alleles of rs2094258 [hazard ratio (HR) = 1.19, 95% confidence interval (CI): 1.02-1.45, <i>P</i> = 0.037] were associated with the long-term survival of GC cases.
|
31558863 |
2019 |
rs2296147
|
|
|
0.030 |
GeneticVariation |
BEFREE |
None of the examined loci were statistically associated with GC risk, although rs2296147 was marginally associated with GC risk (<i>P</i> = 0.050).
|
31558863 |
2019 |
rs3737589
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings showed that the lncRNA <i>TP73-AS1</i> rs3737589 polymorphism might increase the risk of GC, and rs3737589 polymorphism could be a potential biomarker to predict the prognosis of GC patients.
|
31549851 |
2019 |
rs7515164
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study was to reveal the association between lncRNAs <i>TP73-AS1</i> polymorphisms (rs1181865 A > G, rs9800 G > C, rs3737589 A > G, rs2298222 G > A, rs7515164 C > A) and GC in 1000 GC cases and 1000 controls in a Chinese Han population.
|
31549851 |
2019 |
rs2228570
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results indicate that VDR rs731236 & rs2228570 or VDBP rs7041 polymorphisms were not risk factors for the development of gastric cancer individually, however, lower serum levels of vitamin D may be a contributory risk for both predisposition and development of gastric cancer.
|
31549372 |
2019 |
rs7041
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results indicate that VDR rs731236 & rs2228570 or VDBP rs7041 polymorphisms were not risk factors for the development of gastric cancer individually, however, lower serum levels of vitamin D may be a contributory risk for both predisposition and development of gastric cancer.
|
31549372 |
2019 |
rs731236
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results indicate that VDR rs731236 & rs2228570 or VDBP rs7041 polymorphisms were not risk factors for the development of gastric cancer individually, however, lower serum levels of vitamin D may be a contributory risk for both predisposition and development of gastric cancer.
|
31549372 |
2019 |
rs1047972
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our results revealed that AURKA (rs1047972 and rs911160), AURKB (rs2241909 and rs2289590) and AURKC (rs11084490) are associated with a higher risk of GC susceptibility.
|
31521144 |
2019 |
rs2241909
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our results revealed that AURKA (rs1047972 and rs911160), AURKB (rs2241909 and rs2289590) and AURKC (rs11084490) are associated with a higher risk of GC susceptibility.
|
31521144 |
2019 |
rs2289590
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our results revealed that AURKA (rs1047972 and rs911160), AURKB (rs2241909 and rs2289590) and AURKC (rs11084490) are associated with a higher risk of GC susceptibility.
|
31521144 |
2019 |
rs911160
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our results revealed that AURKA (rs1047972 and rs911160), AURKB (rs2241909 and rs2289590) and AURKC (rs11084490) are associated with a higher risk of GC susceptibility.
|
31521144 |
2019 |
rs11084490
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results revealed that AURKA (rs1047972 and rs911160), AURKB (rs2241909 and rs2289590) and AURKC (rs11084490) are associated with a higher risk of GC susceptibility.
|
31521144 |
2019 |
rs4986790
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Nine variants on nine genes were rated as presenting strong cumulative epidemiological evidence for a nominally significant association with GC risk, including <i>APE1</i> (rs1760944), <i>DNMT1</i> (rs16999593), <i>ERCC5</i> (rs751402), <i>GSTT1</i> (null/presence), <i>MDM2</i> (rs2278744), <i>PPARG</i> (rs1801282), <i>TLR4</i> (rs4986790), <i>IL-17F</i> (rs763780), and <i>CASP8</i> (rs3834129).
|
31516756 |
2019 |
rs751402
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Nine variants on nine genes were rated as presenting strong cumulative epidemiological evidence for a nominally significant association with GC risk, including <i>APE1</i> (rs1760944), <i>DNMT1</i> (rs16999593), <i>ERCC5</i> (rs751402), <i>GSTT1</i> (null/presence), <i>MDM2</i> (rs2278744), <i>PPARG</i> (rs1801282), <i>TLR4</i> (rs4986790), <i>IL-17F</i> (rs763780), and <i>CASP8</i> (rs3834129).
|
31516756 |
2019 |
rs763780
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Nine variants on nine genes were rated as presenting strong cumulative epidemiological evidence for a nominally significant association with GC risk, including <i>APE1</i> (rs1760944), <i>DNMT1</i> (rs16999593), <i>ERCC5</i> (rs751402), <i>GSTT1</i> (null/presence), <i>MDM2</i> (rs2278744), <i>PPARG</i> (rs1801282), <i>TLR4</i> (rs4986790), <i>IL-17F</i> (rs763780), and <i>CASP8</i> (rs3834129).
|
31516756 |
2019 |
rs1801282
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Nine variants on nine genes were rated as presenting strong cumulative epidemiological evidence for a nominally significant association with GC risk, including <i>APE1</i> (rs1760944), <i>DNMT1</i> (rs16999593), <i>ERCC5</i> (rs751402), <i>GSTT1</i> (null/presence), <i>MDM2</i> (rs2278744), <i>PPARG</i> (rs1801282), <i>TLR4</i> (rs4986790), <i>IL-17F</i> (rs763780), and <i>CASP8</i> (rs3834129).
|
31516756 |
2019 |
rs16999593
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Nine variants on nine genes were rated as presenting strong cumulative epidemiological evidence for a nominally significant association with GC risk, including <i>APE1</i> (rs1760944), <i>DNMT1</i> (rs16999593), <i>ERCC5</i> (rs751402), <i>GSTT1</i> (null/presence), <i>MDM2</i> (rs2278744), <i>PPARG</i> (rs1801282), <i>TLR4</i> (rs4986790), <i>IL-17F</i> (rs763780), and <i>CASP8</i> (rs3834129).
|
31516756 |
2019 |
rs1760944
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Nine variants on nine genes were rated as presenting strong cumulative epidemiological evidence for a nominally significant association with GC risk, including <i>APE1</i> (rs1760944), <i>DNMT1</i> (rs16999593), <i>ERCC5</i> (rs751402), <i>GSTT1</i> (null/presence), <i>MDM2</i> (rs2278744), <i>PPARG</i> (rs1801282), <i>TLR4</i> (rs4986790), <i>IL-17F</i> (rs763780), and <i>CASP8</i> (rs3834129).
|
31516756 |
2019 |