Variant Gene Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs768678989
rs768678989
MET
0.710 GeneticVariation UNIPROT A novel germ line juxtamembrane Met mutation in human gastric cancer. 11042681

2000

dbSNP: rs768678989
rs768678989
MET
0.710 GeneticVariation BEFREE Here we report a novel germline missense Met mutation, P1009S, in a patient with primary gastric cancer. 11042681

2000

dbSNP: rs63749803
rs63749803
0.700 GeneticVariation UNIPROT hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer. 12132870

2002

dbSNP: rs63750297
rs63750297
0.700 GeneticVariation UNIPROT hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer. 12132870

2002

dbSNP: rs63750623
rs63750623
0.700 GeneticVariation UNIPROT hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer. 12132870

2002

dbSNP: rs63750709
rs63750709
0.700 GeneticVariation UNIPROT hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer. 12132870

2002

dbSNP: rs63750795
rs63750795
0.700 GeneticVariation UNIPROT hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer. 12132870

2002

dbSNP: rs63750966
rs63750966
0.700 GeneticVariation UNIPROT hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer. 12132870

2002

dbSNP: rs63751047
rs63751047
0.700 GeneticVariation UNIPROT hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer. 12132870

2002

dbSNP: rs63751400
rs63751400
0.700 GeneticVariation UNIPROT hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer. 12132870

2002

dbSNP: rs771333219
rs771333219
MET
0.700 GeneticVariation UNIPROT A novel germline mutation in the MET extracellular domain in a Korean patient with the diffuse type of familial gastric cancer. 12920089

2003

dbSNP: rs780759537
rs780759537
0.700 GeneticVariation UNIPROT

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE Our findings demonstrated that rs2294008 and rs2976392 polymorphism of PSCA is a risk-conferring factor associated with increased GC susceptibility, especially in East Asians. 24146278

2014

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE The PSCA rs2294008 C>T polymorphism may be acting through induction of gastric mucosal atrophy, finally leading to development of gastric ulcer and gastric cancer in PSCA rs2294008 T allele carriers, but not duodenal ulcer. 25582162

2015

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE A small meta-analysis including 5 case-control studies showed undoubtedly associations between PSCA rs2294008 and rs2976392 and gastric cancer risk (OR = 1.83, 95% CI: 1.29-2.60 and OR = 1.84, 95% CI: 1.33-2.56, respectively). 20131315

2010

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE Association of PSCA rs2294008 gene variants with poor prognosis and increased susceptibility to gastric cancer and decreased risk of duodenal ulcer disease. 25721731

2015

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE We found that rs2294008 and rs2976392, which were strongly linked to each other (D' = 1.00), were significantly associated with stomach cancer risk. 19582881

2009

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE The two loci of PSCA (rs2294008 and rs2976392) were both significantly associated with GC susceptibility and in linkage disequilibrium. 22426141

2012

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE A recent genome-wide association study (GWAS) linked two single nucleotide polymorphisms (SNPs) in prostate stem cell antigen (PSCA), rs2294008C>T and rs2976392G>A, to risk of diffuse-type of gastric cancer in Japanese and Korean populations. 19554573

2009

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE Our study showed that rs2294008 in the PSCA gene was associated with increased risks of gastric cancer in a Korean population, suggests that rs2294008 might play an important role in gastric carcinogenesis. 21538581

2011

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE These findings supported that PSCA rs2294008 C > T and rs2976392 G > A polymorphisms may contribute to the susceptibility to gastric cancer, particular in non-cardia or diffused gastric cancer. 22481254

2012

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE If validated in further studies, PSCA rs2294008 could be useful marker of survival assessment and individualized clinical therapy for gastric cancer, particularly among the diffuse-type gastric cancer. 21064099

2011

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE The C allele of rs2294008 at PSCA was associated with increased risk of duodenal ulcer (odds ratio (OR) = 1.84; P = 3.92 × 10(-33)) in a recessive model but was associated with decreased risk of gastric cancer (OR = 0.79; P = 6.79 × 10(-12)), as reported previously. 22387998

2012

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE The rs2294008 polymorphism in PSCA increases the risk of noncardia gastric cancer and its precursors in white individuals but protects against proximal cancers. 21070776

2011

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE The rs2294008 C/T polymorphism of the PSCA gene was significantly associated with the susceptibility to GC. 20230293

2010