Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs13361707
rs13361707
0.780 GeneticVariation BEFREE Our study showed that the rs13361707 polymorphism was associated with increased risk of gastric cancer in a Korean population. 23861218

2013

dbSNP: rs13361707
rs13361707
0.780 GeneticVariation BEFREE These findings indicate that the three SNPs (rs4072037, rs13361707 and rs2274223) identified in the GWASs may interact with H. pylori infection to increase the risk of GC. 24069371

2013

dbSNP: rs13361707
rs13361707
0.780 GeneticVariation BEFREE In the dominant model, SNPs rs13361707 [odds ratio (OR) = 1.51, 95%CI: 1.07-2.11)], rs154268 (OR = 1.65, 95%CI: 1.22-2.22), rs6882903 (OR = 1.48, 95%CI: 1.09-2.00), and rs10074991 (OR = 1.53, 95%CI: 1.09-2.16) were significantly associated with an increased risk of gastric cancer. 25024613

2014

dbSNP: rs13361707
rs13361707
0.780 GeneticVariation BEFREE In summary, these results indicated that the C allele of PRKAA1 rs13361707 was a low-penetrate risk factor for GCa. 26485766

2015

dbSNP: rs13361707
rs13361707
0.780 GeneticVariation BEFREE Correlation between protein kinase catalytic subunit alpha-1 gene rs13361707 polymorphism and gastric cancer susceptibility in asian populations. 28978122

2017

dbSNP: rs13361707
rs13361707
0.780 GeneticVariation BEFREE The meta-analysis reveals that the PRKAA1 rs13361707 T>C polymorphism has a significant relationship with increased GC risk. 29620653

2018

dbSNP: rs13361707
rs13361707
0.780 GeneticVariation BEFREE In similar, an increased risk of gastric cancer was also observed for rs13361707 TC genotype (adjusted OR = 1.47, 95%CI: 1.01-2.14, p = 0.043; additive model: adjusted OR = 1.22, 95%CI: 1.02-1.47, p = 0.033). 30253744

2018

dbSNP: rs13361707
rs13361707
0.780 GeneticVariation BEFREE TLR1 rs4833095 SNP was associated with an increased risk of GC in a European population, while PRKAA1 rs13361707 genetic variant was not linked with GC. 30574617

2018

dbSNP: rs9841504
rs9841504
0.720 GeneticVariation BEFREE However, we found no association between rs9841504 and gastric cancer risk. 23861218

2013

dbSNP: rs9841504
rs9841504
0.720 GeneticVariation BEFREE Those subjects with both the risk alleles MUC1 rs9841504 and ZBTB20 rs4072037 had a greater than 3-fold increased risk of gastric cancer. 27127881

2016

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE Aiming to evaluate the associations between host cell proliferation-related genetic polymorphisms and gastric cancer susceptibility, we reviewed the related studies published until 15 September 2008 and quantitatively summarized the associations of the most widely studied polymorphisms (TP53 Arg72Pro, L-myc EcoRI) using meta-analysis. 19536170

2009

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE This meta-analysis suggests that Pro allele in P53 Arg72Pro is significantly associated with the increased risks of digestive tract cancers, especially for Asians, and for gastric cancer, colorectal cancer and gallbladder and pancreatic cancer. 21376265

2011

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE This meta-analysis suggests the Pro variant of TP53 Arg72Pro contributes to gastric cancer risk in Asians. 22631671

2012

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE This meta-analysis suggests that p53 Arg72Pro polymorphism is associated with increased risk of gastric cancer in Asians. 22780299

2012

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE Overall, a significant association was detected between the p53 Arg72Pro polymorphism and GC risk (Pro-allele vs. Arg-allele: OR=1.05, 95%CI=1.01-1.08; Pro/Pro vs. Arg/Arg: OR=1.13, 95%CI=1.04-1.22). 22901123

2012

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE These results suggest that TP53 rs1042522 polymorphism might contribute to the susceptibility of gastric cancer under the dominant model, especially in Eastern Asians. 24534481

2014

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE The purpose of the present hospital-based case-control study was to investigate the association between the miR-34b/c rs4938723 and TP53 Arg72Pro polymorphisms and the risk of gastric cancer. 25190020

2014

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE The p53 R72P seems not to be a potential risk factor for development of GC among Iranian patients, but our data suggest that MDM2 SNP309 might modify the risk related to GC. 25227851

2014

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE We found that the polymorphisms of P53 (rs1042522) and MDM2 (rs2279744) are associated with gastric cancer risk, whereas no significant association was observed between variant genotype of other two polymorphisms (MDM4 rs1380576 and Hausp rs1529916) and gastric cancer risk. 25479941

2015

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE The purpose of this study was to examine the role of the miR-34b/c rs4938723 and TP53 Arg72Pro polymorphisms in the susceptibility of gastric cancer. 25658980

2015

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE In the case-control study, rs1042522 (<i>TP53</i>) was associated with a stronger risk for developing gastric cancer in the sample stratified for diffuse subtype patients when compared to the risk observed for the total cases; CTC haplotype (rs699947/rs833061/rs2010963 <i>VEGFA</i>) was associated with risk while rs699947 was associated with protection for gastric malignancy in the total sample. 30551681

2018

dbSNP: rs1052133
rs1052133
0.100 GeneticVariation BEFREE We examined the distribution of the hOGG1 Ser326Cys polymorphism and its presumed correlation with gastric cancer risk in two case-control studies of different ethnic groups in São Paulo, Brazil. 11448535

2001

dbSNP: rs1052133
rs1052133
0.100 GeneticVariation BEFREE hOGG1 Ser326Cys polymorphism, interaction with environmental exposures, and gastric cancer risk in Japanese populations. 15596047

2004

dbSNP: rs1052133
rs1052133
0.100 GeneticVariation BEFREE To evaluate the association between genetic polymorphisms of X-ray repair cross-complementing group 1 (XRCC1, Arg194Trp and Arg399Gln), adenosine diphosphate ribosyl transferase (ADPRT, Val762Ala), 8-oxoguanine DNA glycosylase (OGG1, Ser326Cys) and apurinic/apyrimidinic endonuclease 1 (APE1, Asp148Glu) and evolution of H.pylori-associated precancerous gastric lesions, a population-based cohort study was conducted in Linqu County, a high-risk area of gastric cancer in China. 19147860

2009

dbSNP: rs1052133
rs1052133
0.100 GeneticVariation BEFREE Although smokers and high salted tea drinkers themselves were at higher risk for gastric cancer (OR=8.975, P=0.0001; OR=14.778, P=0.0001), interaction with OGG1 Ser326Cys did not further modulate the risk. 20593951

2010