Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs397507444
rs397507444
0.100 GeneticVariation BEFREE C677T, A1298C and G1793A) and their haplotypes are associated with the risk of gastric cancer. 15643524

2005

dbSNP: rs397507444
rs397507444
0.100 GeneticVariation BEFREE These results suggest that the MTHFR C677T and A1298C polymorphisms by themselves do not play an important role in the etiology of stomach cancer in the Korean population. 16158971

2005

dbSNP: rs861539
rs861539
0.080 GeneticVariation BEFREE To evaluate the association between polymorphisms XRCC1 Arg194Trp and Arg399Gln and XRCC3 Thr241Met and the risk for chronic gastritis and gastric cancer, in a Southeastern Brazilian population. 16425350

2005

dbSNP: rs1042028
rs1042028
0.010 GeneticVariation BEFREE The prognostic significance of the SULT1A1 Arg213His polymorphism with respect to staging, differentiation and histological type of gastric cancer was also evaluated. 16137826

2005

dbSNP: rs1165109290
rs1165109290
0.010 GeneticVariation BEFREE The association of the manganese superoxide dismutase polymorphisms at -102 C>T and the -9 T>C were not found to be associated with gastric cancer in a Polish case-control study. 15734485

2005

dbSNP: rs4444903
rs4444903
EGF
0.010 GeneticVariation BEFREE We investigated a single nucleotide polymorphism at exon 1 of EGF, named rs4444903 in NCI dbSNP, in 454 Japanese subjects undergoing a health checkup and 202 patients with gastric cancer. 16214932

2005

dbSNP: rs9282861
rs9282861
0.010 GeneticVariation BEFREE The prognostic significance of the SULT1A1 Arg213His polymorphism with respect to staging, differentiation and histological type of gastric cancer was also evaluated. 16137826

2005

dbSNP: rs1217691063
rs1217691063
0.100 GeneticVariation BEFREE Methylenetetrahydrofolate reductase 677C>T polymorphism and gastric cancer susceptibility in Mexico. 16359859

2006

dbSNP: rs1217691063
rs1217691063
0.100 GeneticVariation BEFREE Recently, methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) mutations were discovered to be associated with childhood acute lymphoblastic leukemia (ALL), as well as colon cancer, lymphoma, esophageal and stomach cancer. 16886608

2006

dbSNP: rs1217691063
rs1217691063
0.100 GeneticVariation BEFREE We performed a case-control study to examine the relationship between MTHFR C677T gene polymorphism (MTHFR677C/T) and gastric cancer susceptibility in at-risk populations in central Italy. 16094648

2006

dbSNP: rs1217691063
rs1217691063
0.100 GeneticVariation BEFREE To clarify the influence of MTHFR C677T and A1298C polymorphisms on ga</span>stric cancer (GC), a meta-analysis of eight case-control studies (1,584/2,785 cases/controls) was carried out. 16758123

2006

dbSNP: rs397507444
rs397507444
0.100 GeneticVariation BEFREE Recently, methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) mutations were discovered to be associated with childhood acute lymphoblastic leukemia (ALL), as well as colon cancer, lymphoma, esophageal and stomach cancer. 16886608

2006

dbSNP: rs397507444
rs397507444
0.100 GeneticVariation BEFREE To clarify the influence of MTHFR C677T and A1298C polymorphisms on gastric cancer (GC), a meta-analysis of eight case-control studies (1,584/2,785 cases/controls) was carried out. 16758123

2006

dbSNP: rs1047972
rs1047972
0.030 GeneticVariation BEFREE The results suggest that 169G>A in AURKA is associated with progression of gastric cancer by affecting relative kinase activities of AURKA variants. 16412566

2006

dbSNP: rs775144154
rs775144154
0.020 GeneticVariation BEFREE To test this hypothesis, we evaluated the associations of the G80A polymorphism of RFC1 with EC and GC risk in a case-control study of 216 EC and 633 GC cases and 673 cancer-free controls in a Chinese population. 16962770

2006

dbSNP: rs1051740
rs1051740
0.010 GeneticVariation BEFREE We found an increased risk of gastric cancer for homozygotes for C (histidine) variant in Y113H of EPHX1 (odds ratio, 1.91; 95% confidence interval, 1.19-3.07) compared with subjects with TC/TT. 17164366

2006

dbSNP: rs768231616
rs768231616
0.010 GeneticVariation BEFREE We found an increased risk of gastric cancer for homozygotes for C (histidine) variant in Y113H of EPHX1 (odds ratio, 1.91; 95% confidence interval, 1.19-3.07) compared with subjects with TC/TT. 17164366

2006

dbSNP: rs397507444
rs397507444
0.100 GeneticVariation BEFREE No obvious association between the MTHFR A1298C polymorphism and the risk of stomach cancer was observed in this study. 17438654

2007

dbSNP: rs4986790
rs4986790
0.100 GeneticVariation BEFREE The host response to H. pylori has been related to genetic polymorphisms that influence both innate and adaptive immune responses.Our aim was to investigate whether the presence of the TLR4 Asp299Gly, TLR4 Thr399Ile and IL-8-251 A/T polymorphisms had any influence in the development of distal GC in a Mexican population. 17462092

2007

dbSNP: rs4986790
rs4986790
0.100 GeneticVariation BEFREE Our data suggest that CD14 promoter-159TT and T carrier were associated with lower risk of developing gastric mucosal atrophy in H. pylori infected patients more than 61 years of age, and these genotypes may reduce the risk of intestinal type gastric cancer and TLR4 Asp299Gly, Thr399Ile are very rare in the Japanese population. 19847953

2007

dbSNP: rs4986791
rs4986791
0.070 GeneticVariation BEFREE The host response to H. pylori has been related to genetic polymorphisms that influence both innate and adaptive immune responses.Our aim was to investigate whether the presence of the TLR4 Asp299Gly, TLR4 Thr399Ile and IL-8-251 A/T polymorphisms had any influence in the development of distal GC in a Mexican population. 17462092

2007

dbSNP: rs4986791
rs4986791
0.070 GeneticVariation BEFREE We investigated the effects of common polymorphisms of TLR4 Asp299Gly, Thr399Ile and CD14 promoter -C159T on the risk of gastric cancer including its subtypes and clinicopathologic features. 19847953

2007

dbSNP: rs775144154
rs775144154
0.020 GeneticVariation BEFREE Therefore, we analyzed this polymorphism, the glutamate carboxypeptidase (GCP) II C1561T and the reduced folate carrier (RFC) G80A in a case-control study involving 106 patients with histologically confirmed and characterized gastric cancer with adjustment for other established risk factors for gastric cancer in comparison to 106 age- and sex-matched controls. 17208363

2007

dbSNP: rs1235001018
rs1235001018
0.010 GeneticVariation BEFREE Therefore, we analyzed this polymorphism, the glutamate carboxypeptidase (GCP) II C1561T and the reduced folate carrier (RFC) G80A in a case-control study involving 106 patients with histologically confirmed and characterized gastric cancer with adjustment for other established risk factors for gastric cancer in comparison to 106 age- and sex-matched controls. 17208363

2007

dbSNP: rs1864169
rs1864169
0.010 GeneticVariation BEFREE Therefore, we examined a polymorphism (rs1864169) in the general transcription factor 2A1 (GTF2A1) gene as a test of the hypothesis that this transcription factor and IL-IB gene polymorphisms interact in the effects on the gastric cancer risk due to the possible biological relationship between the two genes. 17596959

2007