|
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In the case-control study, rs1042522 (<i>TP53</i>) was associated with a stronger risk for developing gastric cancer in the sample stratified for diffuse subtype patients when compared to the risk observed for the total cases; CTC haplotype (rs699947/rs833061/rs2010963 <i>VEGFA</i>) was associated with risk while rs699947 was associated with protection for gastric malignancy in the total sample.
|
30551681 |
2018 |
|
rs10434
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The G1612A(rs10434) and C936T(rs3025039) polymorphisms in the 3' untranslated region (3'-UTR) of VEGF gene were genotyped in a total of 844 subjects including 385 GC, 143 ulcer including 98 gastric ulcer (GU), 45 duodenal ulcer (DU), and 316 nonulcer subjects.
|
19496079 |
2009 |
|
rs1044432
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among the nine SNPs, rs11133399 in CLOCK, rs1044432 and rs2279284 in BAML1 were significantly associated with GC overall survival and recurrence-free survival.
|
30843665 |
2019 |
|
rs1045411
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Prognostic Significance of Tag SNP rs1045411 in HMGB1 of the Aggressive Gastric Cancer in a Chinese Population.
|
27116470 |
2016 |
|
rs1045642
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In this preliminary data, the association with MDR1 C3435T polymorphism and risk for developing H. pylori-related gastric cancer and peptic ulcer in Japanese was low.
|
18644389 |
2008 |
|
rs1045642
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Generally, indels rs34743033 and rs16430 were genotyped by PCR and polyacrylamide gel electrophoresis assay and SNPs rs2032582 and rs1045642 were genotyped by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) assay in 110 Chinese AGC patients post-chemotherapy.
|
28074308 |
2017 |
|
rs1045642
|
|
|
0.040 |
GeneticVariation |
BEFREE |
This meta-analysis suggested that the MDR1 C3435T polymorphism is not associated with susceptibility to GC and PU.
|
24815441 |
2014 |
|
rs1045642
|
|
|
0.040 |
GeneticVariation |
BEFREE |
No correlation was observed between the C3435T polymorphism of the MDR1 gene and GC risk or prognosis in the population studied.
|
22641402 |
2012 |
|
rs10464867
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that the A allele of rs10464867 (G>A) was significantly associated with a decreased risk of gastric cancer (odds ratio [OR] = 0.81, 95% confidence interval [95% CI] = 0.71-0.94; P = 4.71×10-3).
|
26402912 |
2015 |
|
rs10474606
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, individuals carrying the THBS4 rs10474606 variant homozygous AA had a modest reduced GC risk.
|
27160021 |
2016 |
|
rs1047768
|
|
|
0.030 |
GeneticVariation |
BEFREE |
In a stratified analysis, rs1047768 T>C was associated with an increased risk of lung cancer, rs2227869 G>C was associated with a decreased risk of cancer in population-based studies, and rs751402 C>T and rs873601 G>A were associated with the risk of gastric cancer.
|
28416771 |
2017 |
|
rs1047768
|
|
|
0.030 |
GeneticVariation |
BEFREE |
For ERCC5, a gene involved in nucleotide excision repair, TC genotype carriers of rs1047768 (OR, 0.65; 95% CI, 0.41-1.03), GC genotype carriers of the nonsynonymous SNP rs2227869 (OR, 0.30; 95% CI, 0.13-0.67), and CCG haplotype carriers of rs1047768, rs17655, and rs2227869 (OR, 0.45; 95% CI, 0.20-1.04) were associated with reduced stomach cancer risk.
|
19661089 |
2009 |
|
rs1047768
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Moreover, in a dominant model, the CG + GG genotype of rs17655 was correlated with an increased risk of gastric cancer compared to the CC genotype (OR = 1.48; 95%CI = 1.00-2.22). rs1047768 and rs751402 were not significantly correlated with an increased or decreased gastric cancer risk.
|
27051028 |
2016 |
|
rs1047840
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The A allele Exol K589E conferred a significant (P = 0.0094) increased risk of gastric cancer.
|
20337148 |
2009 |
|
rs1047972
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The results suggest that 169G>A in AURKA is associated with progression of gastric cancer by affecting relative kinase activities of AURKA variants.
|
16412566 |
2006 |
|
rs1047972
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Based on these results, we can conclude that AURKA rs1047972 and AURKC rs758099 polymorphisms could affect the risk of GC development.
|
27270838 |
2016 |
|
rs1047972
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our results revealed that AURKA (rs1047972 and rs911160), AURKB (rs2241909 and rs2289590) and AURKC (rs11084490) are associated with a higher risk of GC susceptibility.
|
31521144 |
2019 |
|
rs1048369
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There were significant differences in both the genotype and allelic frequency of GPC4 gene (rs1048369) between the EBVaGC and EBVnGC patients.
|
27071854 |
2016 |
|
rs10484761
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetic variation rs10484761 on 6p21.1 derived from a genome-wide association study is associated with gastric cancer survival in a Chinese population.
|
24325909 |
2014 |
|
rs1048943
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Potential Cytochrome P450s (CYPs) 1A1 MspI, 1A1 Ile462Val</span>, 1A2*1 F, and/or 1A2*1C polymorphisms have been implicated in gastric cancer risk among different ethnicities.
|
24443269 |
2014 |
|
rs1048943
|
|
|
0.030 |
GeneticVariation |
BEFREE |
A great number of studies regarding the association between MspI and Ile462Val polymorphisms in the CYP1A1 gene and gastric cancer have been published.
|
22359202 |
2012 |
|
rs1048943
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We examined the association between single nucleotide polymorphisms (SNPs) of CYP1A1 (rs4646421, rs4646422 and rs1048943), GSTM1 and GSTT1 and gastric cancer risk in Japan.
|
27062139 |
2016 |
|
rs10499563
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The IL-6 -6331 (T/C, rs10499563) polymorphism is associated with genetic susceptibility of GC and may have the potential to predict GC risk.
|
24460320 |
2013 |
|
rs10499563
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In contrast, in the Helicobacter pylori positive infection subgroup, rs</span>10499563 TC (adjusted OR=0.64, 95% CI: 0.43-0.95), CC (adjusted OR=0.35, 95% CI: 0.14-0.90), TC/CC (adjusted OR=0.59, 95% CI: 0.40-0.87) genotype were associated with decreased gastric cancer risk, respectively.
|
28442395 |
2017 |
|
rs1050450
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We therefore evaluated the risk of TT genotype in GPX-1 C599T polymorphism with the onset of gastric cancer (P=0.0001; OR=5.41, 95% CI 1.98 to 15.58) and colorectal cancer (P=0.00008; OR=4.40, 95% CI 1.93 to 10.27).
|
27823653 |
2016 |