Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2976392
rs2976392
PSCA ; JRK
0.100 GeneticVariation BEFREE We found that both rs2294008 (CT vs. CC, OR = 1.55, 95% CI = 1.20-1.99, <i>P</i><0.001 and CT+TT vs. CC, OR = 1.38, 95% CI = 1.09-1.74, <i>P</i>=0.008) and rs2976392</span> (GA vs. GG, OR = 1.61, 95% CI = 1.25-2.07, <i>P</i><0.001 and GA+AA vs. GG, OR = 1.52, 95% CI = 1.20-1.92, <i>P</i><0.001) were associated with an increased gastric cancer. 31416884

2019

dbSNP: rs2976392
rs2976392
PSCA ; JRK
0.100 GeneticVariation BEFREE PSCA rs2294008/rs2976392 showed a significant, multiplicative interaction with H. pylori infection in risk of GC. 28220687

2017

dbSNP: rs2976392
rs2976392
PSCA ; JRK
0.100 GeneticVariation BEFREE For SNP rs2976392, the variant A genotypes were also associated with an increased GCa risk (AG vs GG, OR=1.61, 95% CI=1.35-1.91 and AG+AA vs GG, OR=1.47, 95% CI=1.25-1.74). 26848528

2016

dbSNP: rs2976392
rs2976392
PSCA ; JRK
0.100 GeneticVariation BEFREE Specifically, a significant increased stomach cancer risk was associated with PSCA rs2294008 (CT vs. CC: adjusted OR = 1.37, 95% CI = 1.07-1.74, and CT/TT vs.CC: adjusted OR = 1.30, 95% CI = 1.03-1.63), PSCA rs2976392 (AG vs. GG: adjusted OR = 1.30, 95% CI = 1.02-1.65, and AG/AA vs. GG: adjusted OR = 1.26, 95% CI = 1.00-1.59), or PLCE1 rs2274223 (AG vs. AA: adjusted OR = 1.48, 95% CI = 1.15-1.90, and AG/GG vs. AA: adjusted OR = 1.45, 95% CI = 1.14-1.84), respectively. 25658482

2015

dbSNP: rs2976392
rs2976392
PSCA ; JRK
0.100 GeneticVariation BEFREE Our findings demonstrated that rs2294008 and rs2976392 polymorphism of PSCA is a risk-conferring factor associated with increased GC susceptibility, especially in East Asians. 24146278

2014

dbSNP: rs2976392
rs2976392
PSCA ; JRK
0.100 GeneticVariation BEFREE Polymorphisms of PSCA (rs2976392, rs2294008) and MUC1 (rs4072037) genes are associated with GC and HRAG. 25503145

2014

dbSNP: rs2976392
rs2976392
PSCA ; JRK
0.100 GeneticVariation BEFREE These findings supported that PSCA rs2294008 C > T and rs2976392 G > A polymorphisms may contribute to the susceptibility to gastric cancer, particular in non-cardia or diffused gastric cancer. 22481254

2012

dbSNP: rs2976392
rs2976392
PSCA ; JRK
0.100 GeneticVariation BEFREE The two loci of PSCA (rs2294008 and rs2976392) were both significantly associated with GC susceptibility and in linkage disequilibrium. 22426141

2012

dbSNP: rs2976392
rs2976392
PSCA ; JRK
0.100 GeneticVariation BEFREE Although modest limitations and potential bias cannot be eliminated, this meta-analysis suggests that PSCA -rs2294008C>T and -rs2976</span>392G>A are potential factors of GC development for Eastern Asians, and future work may incorporate these findings and evaluate these variants as potential markers for screening and early diagnosis of GC. 22155405

2012

dbSNP: rs2976392
rs2976392
PSCA ; JRK
0.100 GeneticVariation BEFREE Two single nucleotide polymorphisms (SNPs) (rs2976392 and rs2294008) in the PSCA gene were recently identified as the susceptibility loci of gastric cancer, especially in diffuse type. 20131315

2010

dbSNP: rs2976392
rs2976392
PSCA ; JRK
0.100 GeneticVariation BEFREE We found that rs2294008 and rs2976392, which were strongly linked to each other (D' = 1.00), were significantly associated with stomach cancer risk. 19582881

2009