Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1057519815
rs1057519815
G 0.700 GeneticVariation CLINVAR C-RAF mutations confer resistance to RAF inhibitors. 23737487

2013

dbSNP: rs727505017
rs727505017
G 0.700 GeneticVariation CLINVAR C-RAF mutations confer resistance to RAF inhibitors. 23737487

2013

dbSNP: rs368807126
rs368807126
0.010 GeneticVariation BEFREE RNA-seq mutation data implicated CRAF R391W as the alternative driver mutation of this melanoma. 27273450

2016

dbSNP: rs765857063
rs765857063
0.010 GeneticVariation BEFREE Conversely, RNAi-mediated silencing of endogenous RAC1 P29S in a melanoma cell line with a co-occurring BRAF V600 mutation increased sensitivity to vemurafenib and dabrafenib. 25056119

2014

dbSNP: rs750697353
rs750697353
0.010 GeneticVariation BEFREE We studied global gene expression in three melanoma cell lines with the most common and potent V600E mutation in the B-RAF gene-four cell lines with a common Q61R mutation in the N-RAS gene and three cell lines with no mutations using human HG-U133A 2.0 micro-arrays with 22 277 transcripts. 15760917

2005