Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1393350
rs1393350
A 0.800 GeneticVariation GWASCAT Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma. 28212542

2017

dbSNP: rs1393350
rs1393350
0.800 GeneticVariation GWASDB A unique genome-wide association analysis in extended Utah high-risk pedigrees identifies a novel melanoma risk variant on chromosome arm 10q. 21706340

2012

dbSNP: rs1393350
rs1393350
A 0.800 GeneticVariation GWASDB Genome-wide association study identifies three new melanoma susceptibility loci. 21983787

2011

dbSNP: rs1393350
rs1393350
A 0.800 GeneticVariation GWASCAT Genome-wide association study identifies three new melanoma susceptibility loci. 21983787

2011

dbSNP: rs1393350
rs1393350
A 0.800 GeneticVariation GWASDB Genome-wide association study identifies three loci associated with melanoma risk. 19578364

2009

dbSNP: rs1393350
rs1393350
A 0.800 GeneticVariation GWASCAT Genome-wide association study identifies three loci associated with melanoma risk. 19578364

2009

dbSNP: rs1126809
rs1126809
A 0.730 GeneticVariation GWASDB Identification of a melanoma susceptibility locus and somatic mutation in TET2. 24980573

2014

dbSNP: rs1126809
rs1126809
0.730 GeneticVariation BEFREE The association with melanoma of the TYR variant p.Arg402Gln was also statistically significant (OR: 1.50; 95% CI: 1.11-2.04; p-value=0.0089). 22464347

2012

dbSNP: rs1126809
rs1126809
0.730 GeneticVariation BEFREE The homozygous p.R402Q variant was significantly associated with SK risk (P value=0.008; OR=1.57), and was mostly associated with multiple CM risk (P value=0.021; OR=2.50) and familial CM risk (P value=0.022; OR=2.16). 21906913

2011

dbSNP: rs1126809
rs1126809
0.730 GeneticVariation BEFREE The variant in TYR encoding the R402Q amino acid substitution, previously shown to affect eye color and tanning response, conferred risk of CM (OR = 1.21, P = 2.8 x 10(-7)) and BCC (OR = 1.14, P = 6.1 x 10(-4)). 18488027

2008

dbSNP: rs1847134
rs1847134
0.700 GeneticVariation GWASCAT Identification of a melanoma susceptibility locus and somatic mutation in TET2. 24980573

2014

dbSNP: rs10830253
rs10830253
TYR
0.010 GeneticVariation BEFREE In a multivariable model that included only the most statistically significant findings from univariable modeling and adjusted for pigmentary phenotype, back nevi, and baseline features, we found TERT/CLPTM1L rs401681 (P = 0.004), TYRP1 rs2733832 (P = 0.006), MTAP rs1335510 (P = 0.0005), TYR rs10830253 (P = 0.003), and MX2 rs45430 (P = 0.008) to be significantly associated with multiple primary melanoma, while NCOA6 rs4911442 approached significance (P = 0.06). 25837821

2015