rs1393350
|
|
A |
0.800 |
GeneticVariation |
GWASCAT |
Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.
|
28212542 |
2017 |
rs1393350
|
|
|
0.800 |
GeneticVariation |
GWASDB |
A unique genome-wide association analysis in extended Utah high-risk pedigrees identifies a novel melanoma risk variant on chromosome arm 10q.
|
21706340 |
2012 |
rs1393350
|
|
A |
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies three new melanoma susceptibility loci.
|
21983787 |
2011 |
rs1393350
|
|
A |
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies three new melanoma susceptibility loci.
|
21983787 |
2011 |
rs1393350
|
|
A |
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies three loci associated with melanoma risk.
|
19578364 |
2009 |
rs1393350
|
|
A |
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies three loci associated with melanoma risk.
|
19578364 |
2009 |
rs1126809
|
|
A |
0.730 |
GeneticVariation |
GWASDB |
Identification of a melanoma susceptibility locus and somatic mutation in TET2.
|
24980573 |
2014 |
rs1126809
|
|
|
0.730 |
GeneticVariation |
BEFREE |
The association with melanoma of the TYR variant p.Arg402Gln was also statistically significant (OR: 1.50; 95% CI: 1.11-2.04; p-value=0.0089).
|
22464347 |
2012 |
rs1126809
|
|
|
0.730 |
GeneticVariation |
BEFREE |
The homozygous p.R402Q variant was significantly associated with SK risk (P value=0.008; OR=1.57), and was mostly associated with multiple CM risk (P value=0.021; OR=2.50) and familial CM risk (P value=0.022; OR=2.16).
|
21906913 |
2011 |
rs1126809
|
|
|
0.730 |
GeneticVariation |
BEFREE |
The variant in TYR encoding the R402Q amino acid substitution, previously shown to affect eye color and tanning response, conferred risk of CM (OR = 1.21, P = 2.8 x 10(-7)) and BCC (OR = 1.14, P = 6.1 x 10(-4)).
|
18488027 |
2008 |
rs1847134
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Identification of a melanoma susceptibility locus and somatic mutation in TET2.
|
24980573 |
2014 |
rs10830253
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a multivariable model that included only the most statistically significant findings from univariable modeling and adjusted for pigmentary phenotype, back nevi, and baseline features, we found TERT/CLPTM1L rs401681 (P = 0.004), TYRP1 rs2733832 (P = 0.006), MTAP rs1335510 (P = 0.0005), TYR rs10830253 (P = 0.003), and MX2 rs45430 (P = 0.008) to be significantly associated with multiple primary melanoma, while NCOA6 rs4911442 approached significance (P = 0.06).
|
25837821 |
2015 |