rs11012732
|
|
A |
0.810 |
GeneticVariation |
GWASDB |
We identified a new susceptibility locus for meningioma at 10p12.31 (MLLT10, rs11012732, odds ratio = 1.46, P(combined) = 1.88 × 10(-14)).
|
21804547 |
2011 |
rs11012732
|
|
A |
0.810 |
GeneticVariation |
GWASCAT |
We identified a new susceptibility locus for meningioma at 10p12.31 (MLLT10, rs11012732, odds ratio = 1.46, P(combined) = 1.88 × 10(-14)).
|
21804547 |
2011 |
rs11012732
|
|
|
0.810 |
GeneticVariation |
BEFREE |
We identified a new susceptibility locus for meningioma at 10p12.31 (MLLT10, rs11012732, odds ratio = 1.46, P(combined) = 1.88 × 10(-14)).
|
21804547 |
2011 |
rs2686876
|
|
|
0.710 |
GeneticVariation |
BEFREE |
We identified a new susceptibility locus for meningioma at 11p15.5 (rs2686876, odds ratio = 1.44, P = 9.86 × 10-9).
|
29762745 |
2018 |
rs2686876
|
|
T |
0.710 |
GeneticVariation |
GWASCAT |
We identified a new susceptibility locus for meningioma at 11p15.5 (rs2686876, odds ratio = 1.44, P = 9.86 × 10-9).
|
29762745 |
2018 |
rs121434259
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs1568234664
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs587776563
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs121434592
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Mutations in <i>NF2, TRAF7, SMO, KLF4</i>, and <i>AKT1</i> E17K did not predict RB1 S780 staining or progression in grade 1.5 meningiomas.
|
31615938 |
2020 |
rs4968451
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The polymorphisms rs4968451T>G in BRIP1 were significantly associated with the risk of meningioma (TT vs. TG vs. GG additive, P = 0.005; TT+TG vs. GG dominant, P = 0.015; TT/GT+GG recessive, P = 0.034).
|
29581016 |
2018 |
rs12770228
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our updated meta-analysis provided statistical evidence for the role of <i>MLLT10</i> rs12770228, <i>MTRR</i> rs1801394, and <i>MTHFR</i> rs1801131 in increased susceptibility to meningioma.
|
28405167 |
2017 |
rs1801131
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our updated meta-analysis provided statistical evidence for the role of <i>MLLT10</i> rs12770228, <i>MTRR</i> rs1801394, and <i>MTHFR</i> rs1801131 in increased susceptibility to meningioma.
|
28405167 |
2017 |
rs1801131
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, our meta-analysis suggests that two folate metabolism genetic variants MTRR A66G (rs1801394) and MTHFR A1298C (rs1801131) contribute to genetic susceptibility to meningioma and glioma in adults.
|
28915669 |
2017 |
rs1801394
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Moreover, we found that MTRR A66G (rs1801394) variant genotypes was associated with increased risk of meni</span>ngioma and glioma (G vs. A: OR=1.11, P=0.020; GG vs. AA+AG: OR=1.17, P=0.043; GG vs. AA: OR=1.22, P=0.023).
|
28915669 |
2017 |
rs1801394
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our updated meta-analysis provided statistical evidence for the role of <i>MLLT10</i> rs12770228, <i>MTRR</i> rs1801394, and <i>MTHFR</i> rs1801131 in increased susceptibility to meningioma.
|
28405167 |
2017 |
rs1045485
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The CASP8 D302H polymorphism genotypic frequencies were not statistically significantly different between meningioma cases and controls, with frequencies of GG, GC and CC genotypes of 71.2%, 19,2% and 9.6%; and 57.9%, 36.8% and 5.3%, respectively.
|
26359420 |
2016 |
rs12770228
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The variant 'A' allele in MLLT10 rs12770228 was associated with an increased risk of meningioma (per allele odds ratio: 1.25; 95% confidence interval: 1.02, 1.53; P=0.031).
|
24755950 |
2015 |
rs121434592
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A subset of meningiomas lacking NF2 alterations harbored recurrent oncogenic mutations in AKT1 (p.Glu17Lys) and SMO (p.Trp535Leu) and exhibited immunohistochemical evidence of activation of these pathways.
|
23334667 |
2013 |
rs1217691063
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The current meta-analysis firstly provides evidence that the MTHFR C677T polymorphism may modify the risk for brain tumors, particularly meningioma.
|
23846816 |
2013 |
rs1045485
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We tested the hypothesis that the CASP8 polymorphism D302H may influence risk of meningioma through analysis of five independent series of case patients and controls (n=631 and 637, respectively).
|
18823701 |
2009 |
rs4968451
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We have identified a novel association between rs4968451 and meningioma risk.
|
18270339 |
2008 |
rs1217691063
|
|
|
0.020 |
GeneticVariation |
BEFREE |
C677T gene polymorphism of methylenetetrahydrofolate reductase (MTHFR) in meningiomas and high-grade gliomas.
|
16821630 |
2006 |
rs10936599
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three out of the eight evaluated LTL SNPs were significantly associated with increased meningioma risk (rs10936599: OR 1.14, 95% CI 1.01-1.28, rs2736100: OR 1.13, 95% CI 1.03-1.25, rs9420907: OR 1.22, 95% CI 1.07-1.39).
|
30796745 |
2019 |
rs150766139
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The carrier of c.268C>T (p.Q90*) and 550-1G>A was diagnosed with CRC and meningioma at ages 37 and 45 respectively, being reclassified as attenuated adenomatous polyposis after the cumulative detection of 26 adenomas.
|
31227763 |
2019 |
rs2235544
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The C-allele of the DI01 SNP rs2235544 was related to increased circulating free T3/ free T4 ratio in glioma and meningioma patients, indicating greater T4 to T3 conversion.
|
31452060 |
2019 |