Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs28493229
rs28493229
0.890 GeneticVariation BEFREE SNP rs28493229 in ITPKC was associated with KD and coronary artery complications. 29214786

2018

dbSNP: rs28493229
rs28493229
0.890 GeneticVariation BEFREE Functional single-nucleotide polymorphisms (SNPs) in inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) (rs28493229) and caspase-3 (CASP3) (rs113420705; formerly rs72689236) are associated with susceptibility to Kawasaki's disease (KD). 21987091

2013

dbSNP: rs28493229
rs28493229
0.890 GeneticVariation BEFREE The meta-analyses first revealed significant risk for CALs in KD patients carrying risk allele of rs11340705, and the association of rs28493229 with KD was not observed in the Han Chinese. 23456091

2013

dbSNP: rs28493229
rs28493229
0.890 GeneticVariation BEFREE The inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) gene rs28493229 was recently found to be associated with the risk for KD in the Japanese population, suggesting that the ITPKC gene may contribute to KD susceptibility. 22361738

2012

dbSNP: rs28493229
rs28493229
0.890 GeneticVariation BEFREE Recently, a single nucleotide polymorphism (SNP) of the inositol 1,4,5-triphosphate kinase C (ITPKC), rs28493229, was found to passively confer susceptibility for Kawasaki syndrome (KS) and subsequent coronary arterial lesions. 22498790

2012

dbSNP: rs28493229
rs28493229
0.890 GeneticVariation BEFREE This meta-analysis reveals that the functional polymorphism rs28493229 in ITPKC significantly contributes to the risk of KD. 23065250

2012

dbSNP: rs28493229
rs28493229
0.890 GeneticVariation BEFREE in a cohort from a population with the world's third highest incidence of KD, we demonstrated that the C-allele of ITPKC SNP rs28493229 is associated with KD susceptibility and BCG scar reactivation during the acute phase, although its frequency is lower than that in the Japanese cohort (22.6%), suggesting this SNP contributes to KD susceptibility through induced hyperimmune function reflected in the BCG reactivation. 20805785

2011

dbSNP: rs28493229
rs28493229
0.890 GeneticVariation GWASCAT Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. 22081228

2011

dbSNP: rs28493229
rs28493229
0.890 GeneticVariation BEFREE Taken together, our results indicated that C-allele of ITPKC SNP rs284</span>93229 is associated with the susceptibility and aneurysm formation in KD patients in a Taiwanese population. 21533171

2011

dbSNP: rs28493229
rs28493229
0.890 GeneticVariation GWASDB Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. 22081228

2011

dbSNP: rs28493229
rs28493229
0.890 GeneticVariation BEFREE In conclusion, we did not find a statistically significant association between the ITPKC gene SNP rs28493229 and KD or CALs in Taiwanese children. 20045869

2010

dbSNP: rs1801274
rs1801274
0.880 GeneticVariation BEFREE We performed a genetic association analysis in several KD subgroups categorized by clinical characteristics using the KD-associated variants of the B lymphoid tyrosine kinase (<i>BLK</i>; rs6993775) and Fc gamma receptor II a (<i>FCGR2A</i>; rs1801274) in a large number of case (n=1,011) and control (n=4,533) samples. 30468029

2019

dbSNP: rs1801274
rs1801274
0.880 GeneticVariation BEFREE Now, we show in 1,028 European KD patients that the <i>FCGR2C</i>-ORF haplotype, although nearly absent in Asians, was more strongly associated with susceptibility to KD than rs1801274 in Europeans. 30949161

2019

dbSNP: rs1801274
rs1801274
0.880 GeneticVariation BEFREE In a meta-analysis with 1,461 cases and 5,302 controls, a very strong association of KD with the nonsynonymous SNP rs1801274 (p.His167Arg, previously assigned as p.His131Arg) in FCGR2A was confirmed in males (OR = 1.48, P = 1.43 × 10-7), but not in the females (OR = 1.17, P = 0.055). 28886140

2017

dbSNP: rs1801274
rs1801274
A 0.880 GeneticVariation GWASCAT The present study demonstrates that p.His167Arg, a KD-associated FCGR2A variant, acts as a susceptibility gene in males only. 28886140

2017

dbSNP: rs1801274
rs1801274
0.880 GeneticVariation BEFREE This meta-analysis demonstrates that the FCGR2A rs1801274 G-allele confers susceptibility to KD and UC. 27270653

2016

dbSNP: rs1801274
rs1801274
0.880 GeneticVariation BEFREE Compared with their respective wild type counterparts, rs1801274 AG+GG genotypes and rs3818298 TC+CC genotypes were nominally associated with the reduced risk of KD (OR = 0.77, 95% CI = 0.59-0.99, P = 0.045; OR = 0.74, 95% CI = 0.56-0.98, P = 0.038). 25645453

2015

dbSNP: rs1801274
rs1801274
0.880 GeneticVariation BEFREE These results further confirm that rs1801274 in the FCGR2A gene is significantly associated with increased risk of KD. 25093412

2014

dbSNP: rs1801274
rs1801274
0.880 GeneticVariation BEFREE Significant susceptibility to CALs was found in KD patients with high-risk genotypes at both rs1801274 and rs2857151. 23456091

2013

dbSNP: rs1801274
rs1801274
0.880 GeneticVariation BEFREE We also replicated the association of a functional SNP of FCGR2A (rs1801274, P = 1.6 × 10(-6)) identified in a recently reported GWAS of Kawasaki disease. 22446962

2012

dbSNP: rs1801274
rs1801274
A 0.880 GeneticVariation GWASCAT Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. 22081228

2011

dbSNP: rs1801274
rs1801274
A 0.880 GeneticVariation GWASDB Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. 22081228

2011

dbSNP: rs2736340
rs2736340
0.820 GeneticVariation BEFREE Stratification analysis by diseases suggested FAM167A-BLK rs2736340 had a positive association with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), systemic sclerosis (SSc) and Kawasaki disease, primary Sjogren's syndrome (pSS), primary antiphosholipid syndrome (APS), and myositis. 27105348

2016

dbSNP: rs2254546
rs2254546
0.820 GeneticVariation BEFREE In conclusion, rs2254546 polymorphism might significantly contribute to the risk of KD. 24577620

2014

dbSNP: rs2254546
rs2254546
0.820 GeneticVariation BEFREE As a result, the risk alleles of rs1801274 and rs2254546 were observed significant effect on KD with higher frequencies in 358 patients than those in 815 controls. 23456091

2013