|
rs2228570
|
|
|
0.040 |
GeneticVariation |
BEFREE |
These results suggest that VDR rs2228570 and rs731236 polymorphisms are not related with the risk for MS, and did not confirm interaction between these VDR SNPs and HLADRB1 in the risk for MS.
|
23840333 |
2013 |
|
rs731236
|
|
|
0.040 |
GeneticVariation |
BEFREE |
These results suggest that VDR rs2228570 and rs731236 polymorphisms are not related with the risk for MS, and did not confirm interaction between these VDR SNPs and HLADRB1 in the risk for MS.
|
23840333 |
2013 |
|
rs2228570
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We found weak evidence for an association between the rs731236C allele and MS, while there was no direct association with rs2228570.
|
21816760 |
2012 |
|
rs2228570
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The aim of this study is to measure plasma levels of OPG and RANKL as well as to analyze VDR FokI polymorphism (rs2228570) in MS patients and healthy individuals to detect any potential correlation.
|
22805623 |
2012 |
|
rs2228570
|
|
|
0.040 |
GeneticVariation |
BEFREE |
However, the VDR Fok1 variant (rs2228570), selected for previously positive associations with MS susceptibility and 25(OH)D levels in MS patients showed marginally distorted transmission in DRB15-negative patients (p=0.03).
|
21440908 |
2011 |
|
rs731236
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In conclusion, rs731236 TT VDR genotype modulates VDR expression and confers protection against MS in HLA-DRB1*15-positive individuals.
|
21664963 |
2011 |
|
rs731236
|
|
|
0.040 |
GeneticVariation |
BEFREE |
No significant univariate associations between the polymorphisms, rs11574010 (Cdx-2A > G), rs10735810 (Fok1T > C), or rs731236 (Taq1C > T) and MS risk were observed.
|
19383647 |
2009 |
|
rs731236
|
|
|
0.040 |
GeneticVariation |
BEFREE |
An association of two single-nucleotide polymorphisms (SNPs) of the vitamin D receptor (VDR) gene, Apal (rs7975232) and Taql (rs731236), with multiple sclerosis (MS) has been reported in a Caucasian population.
|
19758194 |
2009 |
|
rs10735810
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The aim of our study was to determine the association between FokI gene polymorphism (rs10735810) and the risk of MS in a cohort of Slovak population and to investigate possible correlations of this SNP with the rate of disease disability progression.
|
25376135 |
2015 |
|
rs10735810
|
|
|
0.030 |
GeneticVariation |
BEFREE |
No significant univariate associations between the polymorphisms, rs11574010 (Cdx-2A > G), rs10735810 (Fok1T > C), or rs731236 (Taq1C > T) and MS risk were observed.
|
19383647 |
2009 |
|
rs10735810
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Fok-I vitamin D receptor gene polymorphism (rs10735810) and vitamin D metabolism in multiple sclerosis.
|
19178954 |
2009 |
|
rs11574010
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, a significant interaction was observed between winter sun exposure during childhood, genotype at rs11574010, and MS risk (P = 0.012), with the 'G' allele conferring an increased risk of MS in the low sun exposure group (</=2 h/day).
|
19383647 |
2009 |
|
rs7975232
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An association of two single-nucleotide polymorphisms (SNPs) of the vitamin D receptor (VDR) gene, Apal (rs7975232) and Taql (rs731236), with multiple sclerosis (MS) has been reported in a Caucasian population.
|
19758194 |
2009 |