Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs17824933
rs17824933
CD6
0.850 GeneticVariation BEFREE The single nucleotide polymorphism (SNP) rs17824933 in the CD6 gene has been identified and validated as a genetic risk factor for the development of MS. 26844569

2016

dbSNP: rs17824933
rs17824933
CD6
0.850 GeneticVariation BEFREE CD6 has recently been identified and validated as risk gene for multiple sclerosis (MS), based on the association of a single nucleotide polymorphism (SNP), rs17824933, located in intron 1. 23638056

2013

dbSNP: rs17824933
rs17824933
CD6
0.850 GeneticVariation BEFREE In the recently published meta-analysis of multiple sclerosis genome-wide association studies De Jager et al. identified three single nucleotide polymorphisms associated to MS: rs17824933 (CD6), rs1800693 (TNFRSF1A) and rs17445836 (61.5 kb from IRF8). 21552549

2011

dbSNP: rs17824933
rs17824933
CD6
0.850 GeneticVariation BEFREE Our recent meta-analysis of genome-wide association studies of multiple sclerosis (MS) identified a new susceptibility locus tagged by a single nucleotide polymorphism, rs17824933 (p = 3.8 × 10(-9)), that is found in a block of linkage disequilibrium containing the CD6 gene. 21849685

2011

dbSNP: rs17824933
rs17824933
CD6
0.850 GeneticVariation GWASDB Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088

2011

dbSNP: rs17824933
rs17824933
CD6
0.850 GeneticVariation BEFREE We also found convincing evidence for allelic imbalance at multiple reporter exonic SNPs in CD6 for two samples heterozygous at the multiple sclerosis-associated variant rs17824933, linking GWA findings with variation in gene expression. 19825846

2010

dbSNP: rs17824933
rs17824933
CD6
G 0.850 GeneticVariation GWASCAT Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. 19525953

2009

dbSNP: rs17824933
rs17824933
CD6
G 0.850 GeneticVariation GWASDB Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. 19525953

2009

dbSNP: rs11230563
rs11230563
0.010 GeneticVariation BEFREE We identified association of haplotypes composed of two non-synonymous SNPs [rs11230563 (R225W) and rs2074225 (A257V)] in the 2(nd) SRCR domain with susceptibility to MS (P max(T) permutation = 1×10(-4)). 23638056

2013

dbSNP: rs112852289
rs112852289
0.010 GeneticVariation BEFREE We identified association of haplotypes composed of two non-synonymous SNPs [rs11230563 (R225W) and rs2074225 (A257V)] in the 2(nd) SRCR domain with susceptibility to MS (P max(T) permutation = 1×10(-4)). 23638056

2013

dbSNP: rs2074225
rs2074225
0.010 GeneticVariation BEFREE We identified association of haplotypes composed of two non-synonymous SNPs [rs11230563 (R225W) and rs2074225 (A257V)] in the 2(nd) SRCR domain with susceptibility to MS (P max(T) permutation = 1×10(-4)). 23638056

2013

dbSNP: rs386754116
rs386754116
0.010 GeneticVariation BEFREE We identified association of haplotypes composed of two non-synonymous SNPs [rs11230563 (R225W) and rs2074225 (A257V)] in the 2(nd) SRCR domain with susceptibility to MS (P max(T) permutation = 1×10(-4)). 23638056

2013