rs17824933
|
|
|
0.850 |
GeneticVariation |
BEFREE |
The single nucleotide polymorphism (SNP) rs17824933 in the CD6 gene has been identified and validated as a genetic risk factor for the development of MS.
|
26844569 |
2016 |
rs17824933
|
|
|
0.850 |
GeneticVariation |
BEFREE |
CD6 has recently been identified and validated as risk gene for multiple sclerosis (MS), based on the association of a single nucleotide polymorphism (SNP), rs17824933, located in intron 1.
|
23638056 |
2013 |
rs17824933
|
|
|
0.850 |
GeneticVariation |
BEFREE |
In the recently published meta-analysis of multiple sclerosis genome-wide association studies De Jager et al. identified three single nucleotide polymorphisms associated to MS: rs17824933 (CD6), rs1800693 (TNFRSF1A) and rs17445836 (61.5 kb from IRF8).
|
21552549 |
2011 |
rs17824933
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Our recent meta-analysis of genome-wide association studies of multiple sclerosis (MS) identified a new susceptibility locus tagged by a single nucleotide polymorphism, rs17824933 (p = 3.8 × 10(-9)), that is found in a block of linkage disequilibrium containing the CD6 gene.
|
21849685 |
2011 |
rs17824933
|
|
|
0.850 |
GeneticVariation |
GWASDB |
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
|
21833088 |
2011 |
rs17824933
|
|
|
0.850 |
GeneticVariation |
BEFREE |
We also found convincing evidence for allelic imbalance at multiple reporter exonic SNPs in CD6 for two samples heterozygous at the multiple sclerosis-associated variant rs17824933, linking GWA findings with variation in gene expression.
|
19825846 |
2010 |
rs17824933
|
|
G |
0.850 |
GeneticVariation |
GWASCAT |
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.
|
19525953 |
2009 |
rs17824933
|
|
G |
0.850 |
GeneticVariation |
GWASDB |
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.
|
19525953 |
2009 |
rs11230563
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified association of haplotypes composed of two non-synonymous SNPs [rs11230563 (R225W) and rs2074225 (A257V)] in the 2(nd) SRCR domain with susceptibility to MS (P max(T) permutation = 1×10(-4)).
|
23638056 |
2013 |
rs112852289
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified association of haplotypes composed of two non-synonymous SNPs [rs11230563 (R225W) and rs2074225 (A257V)] in the 2(nd) SRCR domain with susceptibility to MS (P max(T) permutation = 1×10(-4)).
|
23638056 |
2013 |
rs2074225
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified association of haplotypes composed of two non-synonymous SNPs [rs11230563 (R225W) and rs2074225 (A257V)] in the 2(nd) SRCR domain with susceptibility to MS (P max(T) permutation = 1×10(-4)).
|
23638056 |
2013 |
rs386754116
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified association of haplotypes composed of two non-synonymous SNPs [rs11230563 (R225W) and rs2074225 (A257V)] in the 2(nd) SRCR domain with susceptibility to MS (P max(T) permutation = 1×10(-4)).
|
23638056 |
2013 |