|
rs1131692208
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the general population, separately and combined, CCDC93 p.Pro228Leu is dose-dependently associated with lower LDL-c (P-trend 2.5 × 10-6 to 8.0 × 10-9), with lower risk of MI (P-trend 0.04-0.002) and lower risk of cardiovascular mortality (P-trend 0.005-0.004).
|
31630160 |
2020 |
|
rs11614913
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In summary, these results suggest that <i>miR-196a2</i> rs11614913 T > C locus decreases the susceptibility of CAD in female and MI subgroups.
|
31692368 |
2020 |
|
rs17512204
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the general population, separately and combined, CCDC93 p.Pro228Leu is dose-dependently associated with lower LDL-c (P-trend 2.5 × 10-6 to 8.0 × 10-9), with lower risk of MI (P-trend 0.04-0.002) and lower risk of cardiovascular mortality (P-trend 0.005-0.004).
|
31630160 |
2020 |
|
rs3200401
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Taken together, this study provides additional evidence that genetic variation of the ANRIL rs9632884 and MALAT1 rs3200401 can mediate lipid levels in MI patients.
|
30898706 |
2020 |
|
rs6850
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The CyPA platelet surface expression is associated with mortality whereas CyPA PPIA rs6850 is associated with recurrent MI in patients with symptomatic CAD.
|
31519036 |
2020 |
|
rs9632884
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Taken together, this study provides additional evidence that genetic variation of the ANRIL rs9632884 and MALAT1 rs3200401 can mediate lipid levels in MI patients.
|
30898706 |
2020 |
|
rs10507391
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs2540487 genotype was associated with the risk of MI in overdominant model (P = 0.008). rs12762303 and rs10507391 SNPs were significantly associated with lipid levels in MI patients (P < 0.006-0.008).
|
30678701 |
2019 |
|
rs11786580
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We also found that the C allele and the CC genotype of the rs11786580 are more frequent in patients with myocardial infarction.
|
31578885 |
2019 |
|
rs1234314
|
|
|
0.010 |
GeneticVariation |
BEFREE |
When we stratified eligible studies by type of disease, positive results were observed for rs17568 variant in subjects with acute coronary syndrome (ACS) (allele model: P = 0.04, OR = 0.81, 95%CI, 0.65-0.99), for rs1234314 variant in subjects with coronary artery disease (CAD) (dominant model: P = 0.04, OR = 1.16, 95%CI, 1.00-1.35), for rs3850641 variant in subjects with CAD (recessive model: P = 0.02, OR = 1.42, 95%CI, 1.05-1.90) and myocardial infarction (MI) (recessive model: P = 0.03, OR = 1.49, 95%CI, 1.05-2.11).
|
30614039 |
2019 |
|
rs12363415
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Chronotype was associated with the ARNTL genetic variant rs12363415 in MI patients.
|
30818221 |
2019 |
|
rs12762303
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs2540487 genotype was associated with the risk of MI in overdominant model (P = 0.008). rs12762303 and rs10507391 SNPs were significantly associated with lipid levels in MI patients (P < 0.006-0.008).
|
30678701 |
2019 |
|
rs148267594
|
|
|
0.010 |
GeneticVariation |
BEFREE |
None of studied single genetic variants-F13A1 Val34Leu, THBS2 T/G 3'UTR and THBS4 Ala387Pro-and the extended CC/TT/GG haplotype of F13A1/THBS2/THBS4 genes was associated with MI in young age.
|
30972713 |
2019 |
|
rs17568
|
|
|
0.010 |
GeneticVariation |
BEFREE |
When we stratified eligible studies by type of disease, positive results were observed for rs17568 variant in subjects with acute coronary syndrome (ACS) (allele model: P = 0.04, OR = 0.81, 95%CI, 0.65-0.99), for rs1234314 variant in subjects with coronary artery disease (CAD) (dominant model: P = 0.04, OR = 1.16, 95%CI, 1.00-1.35), for rs3850641 variant in subjects with CAD (recessive model: P = 0.02, OR = 1.42, 95%CI, 1.05-1.90) and myocardial infarction (MI) (recessive model: P = 0.03, OR = 1.49, 95%CI, 1.05-2.11).
|
30614039 |
2019 |
|
rs1867624
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Taken together, this study provides additional evidence that genetic variation of the PECAM1 rs1867624 and HIF1A rs2057482 can mediate lipid levels in MI patients.
|
30678728 |
2019 |
|
rs1883832
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Conclusions:</b> Our work showed a significant association between the -1 C>T (rs1883832) polymorphism of the CD40 gene and MI in the Tunisians.
|
30924686 |
2019 |
|
rs200741295
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, Adora2b D296G knock-in mice were more vulnerable than control mice to myocardial infarction and intentional increases in APIP levels overcame the defective protection of the ADORA2B SNP against ischemic injury.
|
31263105 |
2019 |
|
rs2057482
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Taken together, this study provides additional evidence that genetic variation of the PECAM1 rs1867624 and HIF1A rs2057482 can mediate lipid levels in MI patients.
|
30678728 |
2019 |
|
rs2540487
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs2540487 genotype was associated with the risk of MI in overdominant model (P = 0.008). rs12762303 and rs10507391 SNPs were significantly associated with lipid levels in MI patients (P < 0.006-0.008).
|
30678701 |
2019 |
|
rs2569190
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Numerous published studies have investigated the relationship between the CD14-260C>T (rs2569190) polymorphism and the risk of myocardial infarction (MI).
|
31183977 |
2019 |
|
rs320
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In search of genetic markers of myocardial infarction (MI) risk, which have prognostic significance for Russians, we performed a replication study of MI association with genetic variants of <i>PCSK9</i> (rs562556), <i>APOE</i> (epsilon polymorphism, rs7412 and rs429358), <i>LPL</i> (rs320), <i>MTHFR</i> (rs1801133), <i>eNOS</i> (rs2070744), and the 9p21 region (rs1333049) in 405 patients with MI and 198 controls.
|
29340220 |
2019 |
|
rs41508050
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the meta-analysis of HIF1A, the rs11549465 C > T and rs10873142 T > C polymorphisms, but not rs2057482, rs11549467, and rs41508050, were correlated with overall MI or CAD risk.
|
30678728 |
2019 |
|
rs4810485
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Associations of rs1883832 and rs4810485 polymorphisms of CD40 gene with myocardial infarction in the Tunisian population.
|
30924686 |
2019 |
|
rs498005
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Results:</b> C allele of rs498005 was significantly correlated with increased risk of AF (OR = 1.412, 95%CI = 1.012-1.970), and the association still exited after adjustment by age, gender, the status of smoking and drinking, histories of diabetes, hyperlipidaemia and myocardial infarction (adjusted OR = 1.473, 95%CI = 1.043-2.081).
|
31315459 |
2019 |
|
rs562556
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In search of genetic markers of myocardial infarction (MI) risk, which have prognostic significance for Russians, we performed a replication study of MI association with genetic variants of <i>PCSK9</i> (rs562556), <i>APOE</i> (epsilon polymorphism, rs7412 and rs429358), <i>LPL</i> (rs320), <i>MTHFR</i> (rs1801133), <i>eNOS</i> (rs2070744), and the 9p21 region (rs1333049) in 405 patients with MI and 198 controls.
|
29340220 |
2019 |
|
rs7692387
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated whether homozygotes of the GUCY1A3 rs7692387 risk (G) allele benefited from aspirin in two long-term, randomized placebo-controlled trials of aspirin in primary CVD prevention: the Women's Genome Health Study (WGHS, N = 23 294) and a myocardial infarction (MI, N = 550) and stroke (N = 382) case-control set from the Physician's Health Study (PHS, N = 22 071).
|
31228190 |
2019 |