| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
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0.770 | GeneticVariation | BEFREE | The CDKN2A/B locus (rs2383207, 9p21), identified initially as a susceptibility allele for MI and recently implicated in large vessel stroke, was associated with macroscopic infarct pathology in our autopsy cohort (OR = 1.26, p = 0.031). | 24135527 | 2013 |
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0.770 | GeneticVariation | BEFREE | Genome-wide association studies have identified 2 single-nucleotide polymorphisms (SNPs) on chromosome arm 9p21, rs10757278, and rs2383207 that confer susceptibility to myocardial infarction. | 23454037 | 2013 |
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0.770 | GeneticVariation | BEFREE | Subjects with the rs2383207 GG genotype had a 1.85-fold (P = 0.021) risk for MI when compared with the subjects with the AA genotype. | 21415773 | 2011 |
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|
0.770 | GeneticVariation | BEFREE | Background Two single nucleotide polymorphisms (SNPs, rs10757278 and rs2383207) on chromosome 9p21 have been proved to be associated with myocardial infarction. | 18459066 | 2009 |
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0.770 | GeneticVariation | BEFREE | We related SNPs rs2383207 and rs10757278 to stroke and to myocardial infarction and coronary revascularizations (coronary events) using crude and multivariate adjusted Cox proportional hazards models. | 19293724 | 2009 |
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0.770 | GeneticVariation | BEFREE | Genome-wide single nucleotide polymorphism (SNP) association studies recently identified four SNPs (rs10757274, rs2383206, rs2383207, and rs10757278) on chromosome 9p21 that were associated with coronary artery disease (CAD) and myocardial infarction (MI) in Caucasian populations from northern Europe and North America. | 18066490 | 2008 |
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0.770 | GeneticVariation | BEFREE | Recent genome-wide association studies have identified 4 SNPs on chromosome 9p21 associated with CAD (rs10757274 and rs2383206) and myocardial infarction (MI: rs2383207 and rs10757278) in White populations in Northern Europe and North America. | 18048766 | 2008 |
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0.770 | GeneticVariation | GWASDB | A common variant on chromosome 9p21 affects the risk of myocardial infarction. | 17478679 | 2007 |