Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5770917
rs5770917
CHKB ; CPT1B ; CHKB-CPT1B
0.840 GeneticVariation BEFREE The HLA-DQB1*06:02 allele across all ethnic groups and the rs5770917 variation between CPT1B and CHKB genes in Japanese and Koreans are common genetic susceptibility factors for narcolepsy. 24571861

2014
dbSNP: rs5770917
rs5770917
CHKB ; CPT1B ; CHKB-CPT1B
0.840 GeneticVariation BEFREE The study extends on the observation of a strong multiethnic association of polymorphisms in the TCRA and P2RY11 with narcolepsy, but does not confirm the association of CPT1B/CHKB (rs5770917) in the Chinese population. 22177342

2012
dbSNP: rs5770917
rs5770917
CHKB ; CPT1B ; CHKB-CPT1B
0.840 GeneticVariation BEFREE Stepwise multiple regression analysis revealed that the risk allele (C) for SNP rs5770917 was significantly associated with decreased CPT1B mRNA expression (P = 1.0 × 10(-9)), and the CPT1B expression was higher in the narcolepsy patients than in the controls (P = 0.005). 21358852

2011
dbSNP: rs5770917
rs5770917
CHKB ; CPT1B ; CHKB-CPT1B
C 0.840 GeneticVariation GWASDB We conducted a genome-wide association study using 500K SNP microarrays in 222 Japanese individuals with narcolepsy and 389 Japanese controls, with replication of top hits in 159 Japanese individuals with narcolepsy and 190 Japanese controls, followed by the testing of 424 Koreans, 785 individuals of European descent and 184 African Americans. rs5770917, a SNP located between CPT1B and CHKB, was associated with narcolepsy in Japanese (rs5770917[C], odds ratio (OR) = 1.79, combined P = 4.4 x 10(-7)) and other ancestry groups (OR = 1.40, P = 0.02). 18820697

2008
dbSNP: rs5770917
rs5770917
CHKB ; CPT1B ; CHKB-CPT1B
0.840 GeneticVariation BEFREE We conducted a genome-wide association study using 500K SNP microarrays in 222 Japanese individuals with narcolepsy and 389 Japanese controls, with replication of top hits in 159 Japanese individuals with narcolepsy and 190 Japanese controls, followed by the testing of 424 Koreans, 785 individuals of European descent and 184 African Americans. rs5770917, a SNP located between CPT1B and CHKB, was associated with narcolepsy in Japanese (rs5770917[C], odds ratio (OR) = 1.79, combined P = 4.4 x 10(-7)) and other ancestry groups (OR = 1.40, P = 0.02). 18820697

2008
dbSNP: rs5770917
rs5770917
CHKB ; CPT1B ; CHKB-CPT1B
C 0.840 GeneticVariation GWASCAT We conducted a genome-wide association study using 500K SNP microarrays in 222 Japanese individuals with narcolepsy and 389 Japanese controls, with replication of top hits in 159 Japanese individuals with narcolepsy and 190 Japanese controls, followed by the testing of 424 Koreans, 785 individuals of European descent and 184 African Americans. rs5770917, a SNP located between CPT1B and CHKB, was associated with narcolepsy in Japanese (rs5770917[C], odds ratio (OR) = 1.79, combined P = 4.4 x 10(-7)) and other ancestry groups (OR = 1.40, P = 0.02). 18820697

2008
dbSNP: rs1154155
rs1154155 		C 0.810 GeneticVariation GWASCAT A polymorphism in CCR1/CCR3 is associated with narcolepsy. 25986216

2015
dbSNP: rs1154155
rs1154155 		G 0.810 GeneticVariation GWASCAT ImmunoChip study implicates antigen presentation to T cells in narcolepsy. 23459209

2013
dbSNP: rs1154155
rs1154155 		G 0.810 GeneticVariation GWASDB Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic. 24204295

2013
dbSNP: rs1154155
rs1154155 		G 0.810 GeneticVariation GWASCAT Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic. 24204295

2013
dbSNP: rs1154155
rs1154155 		G 0.810 GeneticVariation GWASDB Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy. 20711174

2010
dbSNP: rs1154155
rs1154155 		G 0.810 GeneticVariation GWASCAT Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy. 20711174

2010
dbSNP: rs1154155
rs1154155 		C 0.810 GeneticVariation GWASCAT Using genome-wide association (GWA) in Caucasians with replication in three ethnic groups, we found association between narcolepsy and polymorphisms in the TRA@ (T-cell receptor alpha) locus, with highest significance at rs1154155 (average allelic odds ratio 1.69, genotypic odds ratios 1.94 and 2.55, P < 10(-21), 1,830 cases, 2,164 controls). 19412176

2009
dbSNP: rs1154155
rs1154155 		0.810 GeneticVariation BEFREE Using genome-wide association (GWA) in Caucasians with replication in three ethnic groups, we found association between narcolepsy and polymorphisms in the TRA@ (T-cell receptor alpha) locus, with highest significance at rs1154155 (average allelic odds ratio 1.69, genotypic odds ratios 1.94 and 2.55, P < 10(-21), 1,830 cases, 2,164 controls). 19412176

2009
dbSNP: rs1154155
rs1154155 		C 0.810 GeneticVariation GWASDB Using genome-wide association (GWA) in Caucasians with replication in three ethnic groups, we found association between narcolepsy and polymorphisms in the TRA@ (T-cell receptor alpha) locus, with highest significance at rs1154155 (average allelic odds ratio 1.69, genotypic odds ratios 1.94 and 2.55, P < 10(-21), 1,830 cases, 2,164 controls). 19412176

2009
dbSNP: rs10995245
rs10995245
ZNF365 ; LOC105378327
A 0.800 GeneticVariation GWASCAT Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic. 24204295

2013
dbSNP: rs10995245
rs10995245
ZNF365 ; LOC105378327
A 0.800 GeneticVariation GWASDB Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic. 24204295

2013
dbSNP: rs10995245
rs10995245
ZNF365 ; LOC105378327
A 0.800 GeneticVariation GWASCAT ImmunoChip study implicates antigen presentation to T cells in narcolepsy. 23459209

2013
dbSNP: rs1551570
rs1551570
PPAN ; ANGPTL6 ; SNORD105 ; PPAN-P2RY11
0.800 GeneticVariation GWASCAT Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic. 24204295

2013
dbSNP: rs1551570
rs1551570
PPAN ; ANGPTL6 ; SNORD105 ; PPAN-P2RY11
0.800 GeneticVariation GWASDB Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic. 24204295

2013
dbSNP: rs2834188
rs2834188 		0.800 GeneticVariation GWASCAT Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic. 24204295

2013
dbSNP: rs2834188
rs2834188 		0.800 GeneticVariation GWASDB Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic. 24204295

2013
dbSNP: rs2854536
rs2854536 		0.800 GeneticVariation GWASDB Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic. 24204295

2013
dbSNP: rs2854536
rs2854536 		0.800 GeneticVariation GWASCAT Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic. 24204295

2013
dbSNP: rs2858884
rs2858884 		A 0.800 GeneticVariation GWASCAT Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy. 20711174

2010