However, in the stratification analysis of histology, we found that the rs11066280 TA/AA genotypes were associated with a poor survival of intestinal-type gastric cancer (log-rank P=0.041, hazard ratio [HR]=1.40, 95% confidence interval [CI]=1.02-1.93), Moreover, this hazardous effect was more prominent among patients with tumor size>5cm, no distant metastasis, chemotherapy and drinking.