Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1308088661
rs1308088661
0.010 GeneticVariation BEFREE In another case, EML4-ALK fusion detected in the primary tumor was associated with ALK G1202R secondary resistance mutation in the post-treatment metastasis. 30946933

2019

dbSNP: rs1131692237
rs1131692237
0.010 GeneticVariation BEFREE Sequencing of the progressing metastasis allowed the identification of the ERBB2 L869R mutation previously associated with resistance to lapatinib in vitro.These results support further clinical investigation aiming to demonstrate that ERBB2-mutational driven therapy can improve patient care irrespective of histology. 29941010

2018

dbSNP: rs767151455
rs767151455
0.010 GeneticVariation BEFREE <i>XRCC1</i> rs1799782 (C194T) polymorphism correlated with tumor metastasis and molecular subtypes in breast cancer. 30568466

2018

dbSNP: rs61552325
rs61552325
0.010 GeneticVariation BEFREE Therefore, we initially studied the effect of rs61552325 on androgen-independent prostate cancer cell metastasis. 28422721

2017

dbSNP: rs1057519816
rs1057519816
0.010 GeneticVariation BEFREE Another patient with the S310F mutation had an apocrine carcinoma with seven lymph nodes positive for metastasis, classified as HER2 3+ by the HercepTest, but which was FISH-negative, as well as ER-negative and PgR-negative. 26642960

2016

dbSNP: rs759478535
rs759478535
0.010 GeneticVariation BEFREE No significant associations were found in relation to susceptibility (CCR2-V64I: OR 1.32; 95 % CI 0.57-3.06; CCR5-∆32: OR 1.04; 95 % CI 0.60-1.81), clinical outcome (tumor size, lymph nodes commitment and/or distant metastasis, TNM staging and nuclear grade) or therapeutic response (recurrence and survival). 25716470

2016

dbSNP: rs1136201
rs1136201
0.010 GeneticVariation BEFREE Polymorphisms of HER2 Ile655Val and cyclin D1 (CCND1) G870A are not associated with breast cancer risk but polymorphic allele of HER2 is associated with nodal metastases. 18237245

2008