|
rs2032582
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In terms of pathological characteristics, the <i>ABCC1</i> SNP rs35628 and the <i>ABCB1</i> SNP rs2032582 were significantly associated with tumor size, the <i>ABCC2</i> SNP rs2273697 was significantly associated with estrogen receptor status, and the <i>ABCG2</i> SNP rs2231142 was significantly associated with axillary lymph node status.
|
31391850 |
2019 |
|
rs1045642
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Following meta-analysis, significant associations were seen for six tumor variants (mutant TP53 and PIK3CA, copy number gain of ERBB2/HER2, CCND1 and FGF3, and chromosomal instability/ploidy) and seven germline polymorphisms: ERCC1 rs3212986, ERCC2 rs1799793, TP53 rs1042522, MDM2 rs2279744, TYMS rs34743033, ABCB1 rs1045642 and MTHFR rs1801133.
|
25214541 |
2015 |
|
rs2032582
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Significant associations of rs2032582 SNP with tumor size, negative HER-2/neu status, and family history of breast carcinoma were found.
|
23093106 |
2012 |
|
rs1045642
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The G2677T and C3435T polymorphisms were studied and immunohistochemical analysis of the tumor and adjacent normal tissue was performed.
|
19192650 |
2009 |
|
rs2032582
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The G2677T and C3435T polymorphisms were studied and immunohistochemical analysis of the tumor and adjacent normal tissue was performed.
|
19192650 |
2009 |
|
rs1045642
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We analyzed the C3435T SNP in the MDR1 gene which is associated with altered cellular drug uptake in matched tumor and normal tissues of 45 patients suffering from colorectal carcinoma.
|
12894567 |
2003 |
|
rs1045642
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The estimated allele frequencies of functional polymorphisms in(of) exon 21 (2677 G>T, Ala893Ser) and exon 26(3435 C>T, Ilel 142I1e) of the MDR] gene were 0.42 and 0.46 in the controls and 0.54 (p=0.035) and 0.60 (p=0.017) in the MSI-H tumors.
|
11980438 |
2002 |
|
rs2032582
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The estimated allele frequencies of functional polymorphisms in(of) exon 21 (2677 G>T, Ala893Ser) and exon 26(3435 C>T, Ilel 142I1e) of the MDR] gene were 0.42 and 0.46 in the controls and 0.54 (p=0.035) and 0.60 (p=0.017) in the MSI-H tumors.
|
11980438 |
2002 |
|
rs1128503
|
|
|
0.020 |
GeneticVariation |
BEFREE |
CC and TC+TT genotype patients with C1236T loci showed statistically significant differences in tumor size stratification (χ=4.006, P=0.045).
|
30779721 |
2019 |
|
rs1128503
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The tumour response to docetaxel was significantly influenced by the SNP C1236T of ABCB1 gene coding for the P-gp.
|
30637776 |
2019 |
|
rs201661522
|
|
|
0.010 |
GeneticVariation |
BEFREE |
It is approved for first-line treatment of patients with advanced non-small cell lung cancer (NSCLC) whose tumors have EGFR exon 19 deletions or exon 21 L858R mutations, and for patients with T790M-positive advanced NSCLC whose disease has progressed on or after EGFR-TKI therapy.
|
30875094 |
2019 |