Gene: PALB2 ×
Source: CLINVAR ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs180177115
rs180177115
PALB2
A 0.700 GeneticVariation CLINVAR A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation. 28240985

2017
dbSNP: rs180177136
rs180177136
PALB2
C 0.700 GeneticVariation CLINVAR

dbSNP: rs515726099
rs515726099
PALB2
G 0.700 GeneticVariation CLINVAR Breast-cancer risk in families with mutations in PALB2. 25099575

2014
dbSNP: rs515726099
rs515726099
PALB2
G 0.700 GeneticVariation CLINVAR PALB2 and breast cancer: ready for clinical translation! 23935381

2013
dbSNP: rs515726099
rs515726099
PALB2
G 0.700 GeneticVariation CLINVAR Prevalence of PALB2 mutations in Australasian multiple-case breast cancer families. 23448497

2013
dbSNP: rs515726099
rs515726099
PALB2
G 0.700 GeneticVariation CLINVAR Rare germline mutations in PALB2 and breast cancer risk: a population-based study. 22241545

2012
dbSNP: rs515726099
rs515726099
PALB2
T 0.700 GeneticVariation CLINVAR

dbSNP: rs515726099
rs515726099
PALB2
G 0.700 GeneticVariation CLINVAR Inherited Mutations in Women With Ovarian Carcinoma. 26720728

2016
dbSNP: rs515726099
rs515726099
PALB2
G 0.700 GeneticVariation CLINVAR Contribution of inherited mutations in the BRCA2-interacting protein PALB2 to familial breast cancer. 21285249

2011
dbSNP: rs515726118
rs515726118
PALB2 ; DCTN5
G 0.700 GeneticVariation CLINVAR Germline mutations in the PALB2 gene are population specific and occur with low frequencies in familial breast cancer. 21618343

2011
dbSNP: rs515726118
rs515726118
PALB2 ; DCTN5
T 0.700 GeneticVariation CLINVAR Germline mutations in the PALB2 gene are population specific and occur with low frequencies in familial breast cancer. 21618343

2011
dbSNP: rs587776405
rs587776405
PALB2 ; DCTN5
T 0.700 GeneticVariation CLINVAR PALB2 sequencing in Italian familial breast cancer cases reveals a high-risk mutation recurrent in the province of Bergamo. 24556926

2014
dbSNP: rs587776405
rs587776405
PALB2 ; DCTN5
T 0.700 GeneticVariation CLINVAR Breast-cancer risk in families with mutations in PALB2. 25099575

2014
dbSNP: rs587776417
rs587776417
PALB2
G 0.700 GeneticVariation CLINVAR

dbSNP: rs587776419
rs587776419
PALB2
G 0.700 GeneticVariation CLINVAR

dbSNP: rs587776419
rs587776419
PALB2
A 0.700 GeneticVariation CLINVAR Breast-cancer risk in families with mutations in PALB2. 25099575

2014
dbSNP: rs587776423
rs587776423
PALB2
A 0.700 GeneticVariation CLINVAR Rare germline mutations in PALB2 and breast cancer risk: a population-based study. 22241545

2012
dbSNP: rs587776423
rs587776423
PALB2
G 0.700 GeneticVariation CLINVAR

dbSNP: rs587776428
rs587776428
PALB2
T 0.700 GeneticVariation CLINVAR Mutation analysis of PALB2 in BRCA1 and BRCA2-negative breast and/or ovarian cancer families from Eastern Ontario, Canada. 25225577

2014
dbSNP: rs587776428
rs587776428
PALB2
T 0.700 GeneticVariation CLINVAR Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer. 26315354

2015
dbSNP: rs587776428
rs587776428
PALB2
T 0.700 GeneticVariation CLINVAR Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease. 24556621

2014
dbSNP: rs587776428
rs587776428
PALB2
T 0.700 GeneticVariation CLINVAR Breast-cancer risk in families with mutations in PALB2. 25099575

2014
dbSNP: rs587776428
rs587776428
PALB2
T 0.700 GeneticVariation CLINVAR Structural basis for recruitment of BRCA2 by PALB2. 19609323

2009
dbSNP: rs587776428
rs587776428
PALB2
T 0.700 GeneticVariation CLINVAR Prevalence of PALB2 mutations in Australian familial breast cancer cases and controls. 26283626

2015
dbSNP: rs587782566
rs587782566
PALB2
T 0.700 GeneticVariation CLINVAR Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer. 17200671

2007