Gene: FBXO11 ×
Source: INFERRED ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs397515875
rs397515875
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR

dbSNP: rs587779204
rs587779204
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer. 27978560

2017
dbSNP: rs587779204
rs587779204
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR Clinical Challenges Associated with Universal Screening for Lynch Syndrome-Associated Endometrial Cancer. 27965287

2017
dbSNP: rs587779204
rs587779204
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR Consequences of universal MSI/IHC in screening ENDOMETRIAL cancer patients for Lynch syndrome. 24933100

2014
dbSNP: rs587779204
rs587779204
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR Prevalence of Lynch syndrome among patients with newly diagnosed endometrial cancers. 24244552

2013
dbSNP: rs587779220
rs587779220
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR Structure of the human MutSalpha DNA lesion recognition complex. 17531815

2007
dbSNP: rs587779220
rs587779220
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR CoDP: predicting the impact of unclassified genetic variants in MSH6 by the combination of different properties of the protein. 23621914

2013
dbSNP: rs587779220
rs587779220
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR Mismatch repair analysis of inherited MSH2 and/or MSH6 variation pairs found in cancer patients. 22581703

2012
dbSNP: rs587779220
rs587779220
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR Impact of an immunohistochemistry-based universal screening protocol for Lynch syndrome in endometrial cancer on genetic counseling and testing. 25617771

2015
dbSNP: rs587779227
rs587779227
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR A multifactorial likelihood model for MMR gene variant classification incorporating probabilities based on sequence bioinformatics and tumor characteristics: a report from the Colon Cancer Family Registry. 22949379

2013
dbSNP: rs587779227
rs587779227
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Targeted sequencing of 36 known or putative colorectal cancer susceptibility genes. 28944238

2017
dbSNP: rs587779227
rs587779227
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Suspected Lynch syndrome associated MSH6 variants: A functional assay to determine their pathogenicity. 28531214

2017
dbSNP: rs587779227
rs587779227
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Combined Microsatellite Instability, MLH1 Methylation Analysis, and Immunohistochemistry for Lynch Syndrome Screening in Endometrial Cancers From GOG210: An NRG Oncology and Gynecologic Oncology Group Study. 26552419

2015
dbSNP: rs587779227
rs587779227
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome. 25980754

2015
dbSNP: rs587779227
rs587779227
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Feasibility of screening for Lynch syndrome among patients with colorectal cancer. 18809606

2008
dbSNP: rs587779227
rs587779227
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database. 24362816

2014
dbSNP: rs587779227
rs587779227
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312

2016
dbSNP: rs587779255
rs587779255
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR

dbSNP: rs587779256
rs587779256
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR

dbSNP: rs587779263
rs587779263
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR

dbSNP: rs587779285
rs587779285
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Utilization of multigene panels in hereditary cancer predisposition testing: analysis of more than 2,000 patients. 24763289

2014
dbSNP: rs587779778
rs587779778
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR Structure of the human MutSalpha DNA lesion recognition complex. 17531815

2007
dbSNP: rs587779778
rs587779778
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR LOVD v.2.0: the next generation in gene variant databases. 21520333

2011
dbSNP: rs587781462
rs587781462
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR LOVD v.2.0: the next generation in gene variant databases. 21520333

2011
dbSNP: rs587781462
rs587781462
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR Longitudinal analysis of treatment-induced genomic alterations in gliomas. 28153049

2017