Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs587782386
rs587782386
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome. 25980754

2015
dbSNP: rs587782386
rs587782386
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants. 22102614

2012
dbSNP: rs587782386
rs587782386
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR Hereditary cancer-associated missense mutations in hMSH6 uncouple ATP hydrolysis from DNA mismatch binding. 18790734

2008
dbSNP: rs587782386
rs587782386
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR Structure of the human MutSalpha DNA lesion recognition complex. 17531815

2007
dbSNP: rs587782386
rs587782386
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR Involvement of hMSH6 in the development of hereditary and sporadic colorectal cancer revealed by immunostaining is based on germline mutations, but rarely on somatic inactivation. 11807791

2002