Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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A | 0.700 | GeneticVariation | CLINVAR | TP53 Mutational Status and Prediction of Benefit from Adjuvant 5-Fluorouracil in Stage III Colon Cancer Patients. | 26425688 | 2015 |
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A | 0.700 | GeneticVariation | CLINVAR | Frequent mutations in TP53 and CDKN2A found by next-generation sequencing of head and neck cancer cell lines. | 22911296 | 2012 |
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A | 0.700 | GeneticVariation | CLINVAR | Mutational status of the TP53 gene as a predictor of response and survival in patients with chronic lymphocytic leukemia: results from the LRF CLL4 trial. | 21483000 | 2011 |
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A | 0.700 | GeneticVariation | CLINVAR | Co-localization of mutant p53 and amyloid-like protein aggregates in breast tumors. | 21056685 | 2011 |
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A | 0.700 | GeneticVariation | CLINVAR | TP53 mutations in Korean patients with non-small cell lung cancer. | 20436704 | 2010 |
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C | 0.700 | GeneticVariation | CLINVAR | Analysis of the DNA-binding activity of p53 mutants using functional protein microarrays and its relationship to transcriptional activation. | 20128691 | 2010 |
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C | 0.700 | GeneticVariation | CLINVAR | Li-Fraumeni and Li-Fraumeni-like syndrome mutations in p53 are associated with exonic methylation and splicing regulatory elements. | 19367569 | 2009 |
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A | 0.700 | GeneticVariation | CLINVAR | p53 gene mutations in esophageal squamous cell carcinoma and their relevance to etiology and pathogenesis: results in Japan and comparisons with other countries. | 17573896 | 2007 |
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A | 0.700 | GeneticVariation | CLINVAR | Oncogenic mutation of the p53 gene derived from head and neck cancer prevents cells from undergoing apoptosis after DNA damage. | 17390010 | 2007 |
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C | 0.700 | GeneticVariation | CLINVAR | Germ-line p53 mutations in 15 families with Li-Fraumeni syndrome. | 7887414 | 1995 |
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A | 0.700 | GeneticVariation | CLINVAR | TP53 gene mutation profile in esophageal squamous cell carcinomas. | 8242631 | 1993 |