Gene: APC ×
Source: CLINVAR ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1131691143
rs1131691143
APC
C 0.700 CausalMutation CLINVAR Novel mutations and phenotypic associations identified through APC, MUTYH, NTHL1, POLD1, POLE gene analysis in Indian Familial Adenomatous Polyposis cohort. 28533537

2017
dbSNP: rs1801155
rs1801155
APC
A 0.700 CausalMutation CLINVAR Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study. 28125075

2017
dbSNP: rs1801155
rs1801155
APC
A 0.700 CausalMutation CLINVAR Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer. 28135145

2017
dbSNP: rs863224820
rs863224820
APC
G 0.700 CausalMutation CLINVAR Gastric cancer in FAP: a concerning rise in incidence. 28185118

2017
dbSNP: rs863225332
rs863225332
APC
TA 0.700 CausalMutation CLINVAR Novel mutations and phenotypic associations identified through APC, MUTYH, NTHL1, POLD1, POLE gene analysis in Indian Familial Adenomatous Polyposis cohort. 28533537

2017
dbSNP: rs1114167568
rs1114167568
APC
T 0.700 CausalMutation CLINVAR Contribution of APC and MUTYH mutations to familial adenomatous polyposis susceptibility in Hungary. 26446593

2016
dbSNP: rs121913332
rs121913332
APC
T 0.700 CausalMutation CLINVAR Contribution of APC and MUTYH mutations to familial adenomatous polyposis susceptibility in Hungary. 26446593

2016
dbSNP: rs121913333
rs121913333
APC
T 0.700 CausalMutation CLINVAR Novel and reported APC germline mutations in Chinese patients with familial adenomatous polyposis. 26625971

2016
dbSNP: rs137854573
rs137854573
APC
T 0.700 CausalMutation CLINVAR Low-level APC mutational mosaicism is the underlying cause in a substantial fraction of unexplained colorectal adenomatous polyposis cases. 26613750

2016
dbSNP: rs137854574
rs137854574
APC
T 0.700 CausalMutation CLINVAR Immunohistochemical analysis of the Wnt/β-catenin signaling pathway in pancreatic neuroendocrine neoplasms. 27574554

2016
dbSNP: rs137854574
rs137854574
APC
T 0.700 CausalMutation CLINVAR Contribution of APC and MUTYH mutations to familial adenomatous polyposis susceptibility in Hungary. 26446593

2016
dbSNP: rs1801155
rs1801155
APC
A 0.700 CausalMutation CLINVAR The APC I1307K allele conveys a significant increased risk for cancer. 26421687

2016
dbSNP: rs1801155
rs1801155
APC
A 0.700 CausalMutation CLINVAR Germline variants in Hamartomatous Polyposis Syndrome-associated genes from patients with one or few hamartomatous polyps. 27146957

2016
dbSNP: rs1801155
rs1801155
APC
A 0.700 CausalMutation CLINVAR Association of APC I1307K and E1317Q polymorphisms with colorectal cancer among Egyptian subjects. 26314409

2016
dbSNP: rs1801155
rs1801155
APC
A 0.700 CausalMutation CLINVAR Evaluation of ACMG-Guideline-Based Variant Classification of Cancer Susceptibility and Non-Cancer-Associated Genes in Families Affected by Breast Cancer. 27153395

2016
dbSNP: rs587779352
rs587779352
APC
T 0.700 CausalMutation CLINVAR Contribution of APC and MUTYH mutations to familial adenomatous polyposis susceptibility in Hungary. 26446593

2016
dbSNP: rs587779352
rs587779352
APC
T 0.700 CausalMutation CLINVAR Gardner Fibroma: Clinical and Histopathologic Implications of Germline APC Mutation Association. 26840078

2016
dbSNP: rs587781392
rs587781392
APC
T 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312

2016
dbSNP: rs587781694
rs587781694
APC
T 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312

2016
dbSNP: rs587782557
rs587782557
APC
C 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312

2016
dbSNP: rs62619935
rs62619935
APC
T 0.700 CausalMutation CLINVAR Contribution of APC and MUTYH mutations to familial adenomatous polyposis susceptibility in Hungary. 26446593

2016
dbSNP: rs730881273
rs730881273
APC
T 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312

2016
dbSNP: rs786203020
rs786203020
APC
A 0.700 CausalMutation CLINVAR Contribution of APC and MUTYH mutations to familial adenomatous polyposis susceptibility in Hungary. 26446593

2016
dbSNP: rs863225310
rs863225310
APC
A 0.700 CausalMutation CLINVAR Novel and reported APC germline mutations in Chinese patients with familial adenomatous polyposis. 26625971

2016
dbSNP: rs876659647
rs876659647
APC
A 0.700 CausalMutation CLINVAR Clinicopathological features of familial adenomatous polyposis in Korean patients. 27158207

2016