|
rs1556445736
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1143679
|
|
|
0.020 |
GeneticVariation |
BEFREE |
CD11b rs1143679 was found to be significantly associated with nephritis, but not with age of disease onset, arthritis, hematological involvement, or neural lesions.
|
29207897 |
2018 |
|
rs2004640
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The presence of the rs2004640 T allele increases the risk of nephritis development in Egyptian children with SLE.
|
28059021 |
2017 |
|
rs2004640
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Data analysis was conducted in three groups: patients with high/low anti-dsDNA antibody titre, lupus nephritis/non-nephritis and disease onset age ≤28 years/>28 years. cDNA samples with defined rs2004640 genotypes were amplified using specific primers and transcripts associated with each of the exon1 variants were detected on polyacrylamide-gel.
|
24697591 |
2015 |
|
rs1143679
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These results showed that the rs1143679 variant is also associated with the risk to SLE in our population and with the risk to specific clinical manifestations, as nephritis and presence of antiphospholipid antibodies.
|
24269694 |
2014 |
|
rs6677604
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, rs6677604 might contribute to the difference of complement activation intensity between IgAVN and IgAN.
|
30838755 |
2020 |
|
rs11864909
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The obtained results suggest an association of rs11864909 with chronic kidney disease secondary to chronic tubulointerstinal nephritis.
|
28954491 |
2017 |
|
rs2234693
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Results The SNP rs2234693 was not associated with SLE per se but the minor allele rs2234693-C was correlated with the presence of nephritis and discoid skin rash.
|
27681518 |
2017 |
|
rs2275913
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interleukin-17A rs2275913, Interleukin-17F rs763780 and rs2397084 gene polymorphisms as possible risk factors in Juvenile lupus and lupus related nephritis.
|
26515887 |
2016 |
|
rs2397084
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interleukin-17A rs2275913, Interleukin-17F rs763780 and rs2397084 gene polymorphisms as possible risk factors in Juvenile lupus and lupus related nephritis.
|
26515887 |
2016 |
|
rs3124954
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Furthermore, an association between the occurrence of nephritis and the T/T genotype for FCN2 rs3124954 SNP (p = 0.047, OR = 3.17, 95%CI = 1.34-7.5) was observed.
|
26464189 |
2016 |
|
rs3819025
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also, our findings showed that the A allele of IL17A rs3819025 was associated with a higher risk of HSP nephritis (OR 1.61; 95 % CI 1.00-2.58; P = 0.047).
|
27021337 |
2016 |
|
rs763780
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interleukin-17A rs2275913, Interleukin-17F rs763780 and rs2397084 gene polymorphisms as possible risk factors in Juvenile lupus and lupus related nephritis.
|
26515887 |
2016 |
|
rs113488022
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Granulomatous nephritis and dermatitis in a patient with BRAF V600E mutant metastatic melanoma treated with dabrafenib and trametinib.
|
26512791 |
2015 |
|
rs121913377
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Granulomatous nephritis and dermatitis in a patient with BRAF V600E mutant metastatic melanoma treated with dabrafenib and trametinib.
|
26512791 |
2015 |
|
rs1800897
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, the frequency of the PAX2 heterozygous genotype 798C>T in the HSP with nephritis (HSPN) group was significantly higher than those in the controls and in the HSP without nephritis group (P<0.05).
|
25385517 |
2015 |
|
rs10127939
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Nephritis among African American patients with SLE was associated with FcγRIIIa low-binding haplotypes containing the 66L/R/H and 176F variants (P = 0.03) and with low-binding genotype combinations (P = 0.002).
|
24782186 |
2014 |
|
rs3758391
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that SIRT1 rs3758391 modifies SLE morbidity, with rs3758391 T allele being a risk factor for nephritis and a higher SLEDAI.
|
24570024 |
2014 |
|
rs1053874
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Q222R polymorphism in DNAse I gene is a risk factor for nephritis in South Indian SLE patients.
|
23963431 |
2013 |
|
rs1718119
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Stratification of cases for the presence of nephritis showed that rs2230911 G allele and CG/(CG+GG) genotypes were at a lower risk of SLE with nephritis (LN) (G versus C, P = 0.011, OR = 0.640, 95% CI: 0.454-0.903; CG versus CC, P = 0.035, OR = 0.645, 95% CI: 0.429-0.970; GG versus CC, P = 0.101, OR = 0.349, 95% CI: 0.099-1.228; CG+GG versus CC, P = 0.015 OR = 0.612, 95% CI: 0.411-0.910), but rs1718119 and rs3751143 were not associated with LN.
|
23435013 |
2013 |
|
rs2230911
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Stratification of cases for the presence of nephritis showed that rs2230911 G allele and CG/(CG+GG) genotypes were at a lower risk of SLE with nephritis (LN) (G versus C, P = 0.011, OR = 0.640, 95% CI: 0.454-0.903; CG versus CC, P = 0.035, OR = 0.645, 95% CI: 0.429-0.970; GG versus CC, P = 0.101, OR = 0.349, 95% CI: 0.099-1.228; CG+GG versus CC, P = 0.015 OR = 0.612, 95% CI: 0.411-0.910), but rs1718119 and rs3751143 were not associated with LN.
|
23435013 |
2013 |
|
rs3751143
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Stratification of cases for the presence of nephritis showed that rs2230911 G allele and CG/(CG+GG) genotypes were at a lower risk of SLE with nephritis (LN) (G versus C, P = 0.011, OR = 0.640, 95% CI: 0.454-0.903; CG versus CC, P = 0.035, OR = 0.645, 95% CI: 0.429-0.970; GG versus CC, P = 0.101, OR = 0.349, 95% CI: 0.099-1.228; CG+GG versus CC, P = 0.015 OR = 0.612, 95% CI: 0.411-0.910), but rs1718119 and rs3751143 were not associated with LN.
|
23435013 |
2013 |
|
rs4958881
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Comparing cases of systemic lupus erythematosus with nephritis and cases of systemic lupus erythematosus without nephritis revealed strong associations with lupus nephritis at rs7708392 in European Americans and rs4958881 in African Americans.
|
23970121 |
2013 |
|
rs7708392
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Comparing cases of systemic lupus erythematosus with nephritis and cases of systemic lupus erythematosus without nephritis</span> revealed strong associations with lupus nephritis at rs7708392 in European Americans and rs4958881 in African Americans.
|
23970121 |
2013 |
|
rs12150220
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results demonstrated that NLRP1 rs2670660 SNP and the NLRP1 rs12150220-rs2670660 A-G haplotype were associated with SLE in our study population, and in particular with the development of nephritis, rash and arthritis.
|
22235789 |
2012 |