| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.100 | GeneticVariation | BEFREE | SNP in the WT1 gene (rs16754) was significantly associated with lower expression of WT1. | 30082223 | 2018 |
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|
0.100 | GeneticVariation | BEFREE | The assay allows evaluating WT1 rs16754 polymorphism in diagnostic routine to improve prognostic information faster and without over-costing for diagnostic laboratories. | 29407184 | 2018 |
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|
0.100 | GeneticVariation | BEFREE | In conclusion, WT1 rs16754 polymorphism is associated with better survival of AML. | 26992216 | 2016 |
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|
0.100 | GeneticVariation | BEFREE | The single-nucleotide polymorphism (SNP) within Wilms tumor-1 (WT1) exon 7, rs16754, has been arguably reported to be implicated in acute myeloid leukemia (AML) prognosis. | 26499507 | 2016 |
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|
0.100 | GeneticVariation | BEFREE | The genetic variant rs16754 of Wilms tumor gene 1 (WT1) has recently been described as an independent prognostic factor in AML patients. | 25932444 | 2015 |
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|
0.100 | GeneticVariation | BEFREE | Wilms tumor gene single nucleotide polymorphism rs16754 predicts a favorable outcome in children with acute lymphoblastic leukemia. | 26224397 | 2015 |
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|
0.100 | GeneticVariation | BEFREE | The Wilms' tumour gene 1 (WT1) single nucleotide polymorphism (SNP) rs16754 has recently been described as an independent prognostic factor in acute myeloid leukaemia (AML) patients. | 23484026 | 2013 |
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|
0.100 | GeneticVariation | BEFREE | At least one copy of the minor SNP rs16754 allele (WT1(AG) or WT1(GG)) was detected in 30 (29 %) patients. | 22895555 | 2012 |
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|
0.100 | GeneticVariation | BEFREE | The high prevalence of WT1 SNP rs16754, and its correlation with improved outcome, identifies WT1 SNP rs16754 as a potentially important molecular marker of prognosis in pediatric AML. | 21189390 | 2011 |
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|
0.100 | GeneticVariation | BEFREE | The frequency of WT1 mutation in the Southeast Asian AML was thus comparable to the figures reported from the West although the designated major allele for rs16754 polymorphism was different. | 21798259 | 2011 |
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|
0.100 | GeneticVariation | BEFREE | Clinical outcome and gene- and microRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study. | 21659357 | 2011 |