rs1801133
|
|
|
0.060 |
GeneticVariation |
BEFREE |
For MTHFR rs1801133 polymorphism, mothers having TT and CT genotypes were more likely to affect NTDs in the offspring (OR = 4.105, 95%CI: 1.271-13.258; OR = 3.333, 95%CI: 1.068-10.400).
|
30867013 |
2019 |
rs1801133
|
|
|
0.060 |
GeneticVariation |
BEFREE |
In conclusion, it can be stated that, rs1801133 was associated with neural tube defects risk in patients from the eastern part of India and it might be counted as a molecular marker for evaluating the susceptibility of NTDs.
|
30120883 |
2018 |
rs1801133
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Our results suggest that rs2236225 of MTHFD1 gene, rs1801133 of MTHFR gene and rs1801394 of MTRR gene were associated with NTDs in Han population of Northern China.
|
29392422 |
2018 |
rs1801133
|
|
|
0.060 |
GeneticVariation |
BEFREE |
There was a COMT rs737865 CC × MTHFR rs1801133 TT interaction for total NTDs (OR = 3.02, 95 % CI = 1.00-9.14) and for anencephaly (OR = 3.39, 95 % CI = 0.94-12.18).
|
24990354 |
2015 |
rs1801133
|
|
|
0.060 |
GeneticVariation |
BEFREE |
For mothers in the lowest folate-intake group, risk of NTDs in offspring was significantly decreased for maternal MTHFR SNPs rs1476413, rs1801131, and rs1801133 (odds ratio [OR] = 0.55, 80% confidence interval [CI]: 0.20, 1.48; OR = 0.58, 80% CI: 0.24, 1.43; OR = 0.69, 80% CI: 0.41, 1.17, respectively), and TYMS SNPs rs502396 and rs699517 (OR = 0.91, 80% CI: 0.53, 1.56; OR = 0.70, 80% CI: 0.38, 1.29).
|
22903727 |
2012 |
rs1801133
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Gene variants in the folate metabolic pathway (e.g., MTHFR rs1801133 (677 C > T) and MTHFD1 rs2236225 (R653Q)) have been found to increase NTD risk.
|
22856873 |
2012 |