rs1805087
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The BHMT gene rs3733890, RFC1 gene rs1051266 and MTR gene rs1805087 were associated with the occurrence of NTDs in Han population of Northern China.
|
28770393 |
2018 |
rs1805087
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Furthermore, the result of the meta-analysis supported the association between MTRR 66A>G and NTDs risk (G allele vs. A allele: OR = 1.32, 95% CI = 1.09-1.61, GG + GA vs. AA: OR = 1.49, 95% CI = 1.06-2.09, GG vs. AA: OR = 1.61, 95% CI = 1.04-2.49).Our study confirmed that the MTRR 66A>G and MTR 2756A>G were significantly associated with the increased NTDs risk in a Chinese population.
|
26334892 |
2015 |
rs1805087
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The present meta-analysis indicated that MTRR A66G polymorphism, but not MTR A2756G, is significantly associated with maternal risk for NTDs in Caucasians.
|
23266814 |
2013 |
rs1805087
|
|
|
0.090 |
GeneticVariation |
BEFREE |
To sum up, no associations between the MTR A2756G polymorphism and NTD risk were found among the 3 groups in all genetic models.
|
23438943 |
2013 |
rs1805087
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Interaction between maternal 5,10-methylenetetrahydrofolate reductase C677T and methionine synthase A2756G gene variants to increase the risk of fetal neural tube defects in a Shanxi Han population.
|
23489792 |
2013 |
rs1805087
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The present meta-analyses indicate that MTR A2756G and MTRR A66G polymorphism are not associated with NTD risks in Caucasian children.
|
23425389 |
2013 |
rs1805087
|
|
|
0.090 |
GeneticVariation |
BEFREE |
No significant NTD association was found with S175L or K350R in cases or their parents and no interactions were observed between these polymorphisms and the D919G variant of MTR or the A222V variant of 5,10-methylenetetrahydrofolate reductase (MTHFR).
|
15979034 |
2005 |
rs1805087
|
|
|
0.090 |
GeneticVariation |
BEFREE |
We detected MTR A2756G and MTRR A66G polymorphisms using PCR-RFLP analysis in a group of NTD infants, their mothers and normal controls.
|
12649067 |
2003 |
rs1805087
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The D919G mutation does not seem to be a risk factor for NTD or vascular disease.
|
9327029 |
1997 |