Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3733890
rs3733890
BHMT ; DMGDH
0.030 GeneticVariation BEFREE The BHMT gene rs3733890, RFC1 gene rs1051266 and MTR gene rs1805087 were associated with the occurrence of NTDs in Han population of Northern China. 28770393

2018
dbSNP: rs3733890
rs3733890
BHMT ; DMGDH
0.030 GeneticVariation BEFREE MTHM 501A>G only in case of GDM, and BHMT 716G>A only in case of no folate supplementation contribute to the etiology of NTDs. 24326202

2014
dbSNP: rs3733890
rs3733890
BHMT ; DMGDH
0.030 GeneticVariation BEFREE Since genetic deficiencies in folate-dependent homocysteine metabolism have been identified in NTD families, we investigated a common variant in betaine-homocysteine methyltransferase (BHMT), 742G-->A (R239Q), as a genetic modifier of NTD risk. 12749058

2003