Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1801160
rs1801160
DPYD ; DPYD-AS1
0.040 GeneticVariation BEFREE Univariate analysis allowed the selection of c.1905+1G>A, c.2194G>A and c.2846A>T alleles as significantly associated with gastrointestinal and hematological ADRs (p < 0.05), while the c.496A>G variant showed a positive trend of association with neutropenia (p = 0.06). 30723313

2019
dbSNP: rs1801160
rs1801160
DPYD ; DPYD-AS1
0.040 GeneticVariation BEFREE The additional DPYD polymorphisms could enhance the prevention of fluoropyrimidine toxicity. c.2194G>A is the most frequent polymorphism and it was found to be associated with neutropenia. 30858516

2019
dbSNP: rs1801160
rs1801160
DPYD ; DPYD-AS1
0.040 GeneticVariation BEFREE *6 rs1801160 (FDR<0.0001), and *2A rs3918290 (FDR=0.0004) variant alleles were significantly associated with time to neutropenia. 29065426

2017
dbSNP: rs1801160
rs1801160
DPYD ; DPYD-AS1
0.040 GeneticVariation BEFREE Moreover, we identified a strong association of V732I with leucopenia (OR = 8.17; 95%CI 2.44 - 27.31) and neutropenia (OR=2.78; 95% CI 1.03-7.51). 19473056

2009