|
rs1057519847
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Inclusion criteria were histologic diagnosis of benign nodule (control) and stage I or II adenocarcinoma harboring either p.L858R or exon19 delEGFR mutations.
|
30309763 |
2018 |
|
rs1057519848
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Inclusion criteria were histologic diagnosis of benign nodule (control) and stage I or II adenocarcinoma harboring either p.L858R or exon19 delEGFR mutations.
|
30309763 |
2018 |
|
rs121434568
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Inclusion criteria were histologic diagnosis of benign nodule (control) and stage I or II adenocarcinoma harboring either p.L858R or exon19 delEGFR mutations.
|
30309763 |
2018 |
|
rs113488022
|
|
|
0.020 |
GeneticVariation |
BEFREE |
When microdissected and sequenced separately, one nodule was positive for BRAF (v-raf murine sarcoma viral oncogene homolog B1) V600E and the other nodule was wild type at the BRAF codon 600.
|
27597976 |
2016 |
|
rs121913377
|
|
|
0.020 |
GeneticVariation |
BEFREE |
When microdissected and sequenced separately, one nodule was positive for BRAF (v-raf murine sarcoma viral oncogene homolog B1) V600E and the other nodule was wild type at the BRAF codon 600.
|
27597976 |
2016 |
|
rs1057519847
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The coexpression of HER2 and EGFR L858R in a solitary nodule removed from the lung, whose mutation was not confirmed by molecular techniques, made us think about the possible existence of a cross-reaction between HER2 and the EGFR L858R-specific antibody.
|
25390349 |
2015 |
|
rs1057519848
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The coexpression of HER2 and EGFR L858R in a solitary nodule removed from the lung, whose mutation was not confirmed by molecular techniques, made us think about the possible existence of a cross-reaction between HER2 and the EGFR L858R-specific antibody.
|
25390349 |
2015 |
|
rs121434568
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The coexpression of HER2 and EGFR L858R in a solitary nodule removed from the lung, whose mutation was not confirmed by molecular techniques, made us think about the possible existence of a cross-reaction between HER2 and the EGFR L858R-specific antibody.
|
25390349 |
2015 |
|
rs113488022
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Before undergoing thyroidectomy, we performed molecular diagnostic tests that revealed the absence of BRAF(V600E) and the presence of RET/PTC-1 in one nodule and RET/PTC-3 in the two others.
|
21048359 |
2010 |
|
rs121913377
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Before undergoing thyroidectomy, we performed molecular diagnostic tests that revealed the absence of BRAF(V600E) and the presence of RET/PTC-1 in one nodule and RET/PTC-3 in the two others.
|
21048359 |
2010 |
|
rs375878504
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The fine-needle aspirate of the nodule was examined with next-generation sequencing and found to harbor a C228T mutation in the TERT gene, a Q61R mutation in the HRAS gene, and an A113_splice mutation in the EIF1AX gene.
|
29669480 |
2018 |
|
rs121434569
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this case report, we described a 37-year-old woman who underwent refractory after second-line gefitinib therapy and was confirmed to have SCLC transformation without the T790M mutation in the left lobar nodule, but concomitant with the plasma-genotyped EGFR T790M mutation.
|
28723866 |
2017 |
|
rs765808222
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three patients were heterozygous for different missense mutations located in the highly conserved β nodule: c.882G>C:Arg294Ser (Arg264Ser), c.1298G>T:Trp433Leu (Trp403Leu) and c.1329C>G:Asn443Lys (Asn413Lys).
|
28306188 |
2017 |
|
rs2069852
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Pretransplant hepatitis B virus DNA (P = 0.014), pretransplant serum alpha-fetoprotein (P = 0.035), number of nodules (P = 0.011), diameter of main nodule (P = 0.001), macrovascular invasion (P = 0.001), microvascular invasion (P = 0.001), HCC exceeding the Milan criteria (P < 0.001), and donor rs2069852 AA genotype (P = 0.010) were associated with HCC recurrence.
|
27368337 |
2016 |
|
rs372043866
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The coexpression of HER2 and EGFR L858R in a solitary nodule removed from the lung, whose mutation was not confirmed by molecular techniques, made us think about the possible existence of a cross-reaction between HER2 and the EGFR L858R-specific antibody.
|
25390349 |
2015 |
|
rs386352319
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In 1 adrenal harboring the KCNJ5 p.Gly151Arg mutation in the principal nodule, the same mutation was present in 2 secondary nodules, but no mutation was found in a third nodule.
|
26351028 |
2015 |
|
rs121913529
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The first case was a 72-year-old male with a nodule (12 × 10 mm) detected by CT. Macroscopically, it contained abundant mucin; histopathologically, goblet cells were predominant, whereas ciliated and basal cells were sparse.A KRAS G12V mutation was detected.
|
25229323 |
2014 |
|
rs121912532
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The D578H-LHR mutation was found in the adenoma or nodule with hyperplasia in all but two patients.
|
21490077 |
2011 |
|
rs121908864
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The mis-sense mutations were Met-452-->Thr in 17 cats (35 nodules), Ser-504-->Arg (two different mutational forms) in two cats (two nodules), Val-508-->Arg in one cat (three nodules), Arg-530-->Gln in one cat (two nodules), Val-557-->Leu in 13 cats (36 nodules), Thr-631-->Ala or Thr-631-->Phe (each mutation seen in one nodule of one cat), Asp-632-->Tyr in six cats (10 nodules) and Asp-632-->His in one cat (one nodule).
|
16135672 |
2005 |
|
rs28937584
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The mis-sense mutations were Met-452-->Thr in 17 cats (35 nodules), Ser-504-->Arg (two different mutational forms) in two cats (two nodules), Val-508-->Arg in one cat (three nodules), Arg-530-->Gln in one cat (two nodules), Val-557-->Leu in 13 cats (36 nodules), Thr-631-->Ala or Thr-631-->Phe (each mutation seen in one nodule of one cat), Asp-632-->Tyr in six cats (10 nodules) and Asp-632-->His in one cat (one nodule).
|
16135672 |
2005 |
|
rs750198847
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The mis-sense mutations were Met-452-->Thr in 17 cats (35 nodules), Ser-504-->Arg (two different mutational forms) in two cats (two nodules), Val-508-->Arg in one cat (three nodules), Arg-530-->Gln in one cat (two nodules), Val-557-->Leu in 13 cats (36 nodules), Thr-631-->Ala or Thr-631-->Phe (each mutation seen in one nodule of one cat), Asp-632-->Tyr in six cats (10 nodules) and Asp-632-->His in one cat (one nodule).
|
16135672 |
2005 |
|
rs764330550
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The mis-sense mutations were Met-452-->Thr in 17 cats (35 nodules), Ser-504-->Arg (two different mutational forms) in two cats (two nodules), Val-508-->Arg in one cat (three nodules), Arg-530-->Gln in one cat (two nodules), Val-557-->Leu in 13 cats (36 nodules), Thr-631-->Ala or Thr-631-->Phe (each mutation seen in one nodule of one cat), Asp-632-->Tyr in six cats (10 nodules) and Asp-632-->His in one cat (one nodule).
|
16135672 |
2005 |
|
rs104894359
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Only one point mutation could be found in the N-ras gene codon 61 (Gly to Arg) in a cold adenomatous nodule which was monoclonal.
|
11531932 |
2001 |
|
rs1363782162
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Only one point mutation could be found in the N-ras gene codon 61 (Gly to Arg) in a cold adenomatous nodule which was monoclonal.
|
11531932 |
2001 |