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rs17817449
|
|
|
0.890 |
GeneticVariation |
BEFREE |
Risk allele carriers of rs17817449 SNP had somewhat higher values of weight, body mass index, waist and hip circumference, total cholesterol, triglycerides, adiponectin, and fasting glucose.This study revealed the genetic association between rs9939609 SNP of FTO and obesity in a Romanian population, and to the authors' knowledge, this is the first study to investigate this association in a Romanian population.
|
27196486 |
2016 |
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rs17817449
|
|
|
0.890 |
GeneticVariation |
BEFREE |
In single locus analysis, FTO rs8050136 CA (p = 0.0001; OR (95% CI) = 2.4 (1.7-3.4) and AA (p = 0.0001; OR (95% CI) = 3.1 (1.9-5.2); FTO rs1421085 TA (p = 0.0001; OR (95% CI) = 2.1 (1.4-3.0) and AA (p = 0.0001; OR (95% CI) = 3.0 (1.8-5.0); FTO rs9939609 TC (p = 0.0001; OR (95% CI) = 2.1 (1.5-3.1) and CC (p = 0.0001; OR (95% CI) = 4.2 (2.5-7.3) along with TG (p = 0.001; OR (95% CI) = 2.1 (1.3-3.2) and GG (p = 0.021; OR (95% CI) = 3.8 (1.2-11.8) genotypes of FTO rs17817449 with GT (p = 0.0001; OR (95% CI) = 2.1 (1.5-3.1) and TT (p = 0.012; OR (95% CI) = 3.3 (1.8-3.6) genotypes of IRX3 rs3751723 were significantly associated with obesity.
|
26440677 |
2016 |
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rs17817449
|
|
|
0.890 |
GeneticVariation |
BEFREE |
The SNPs rs1421085, rs17817449 and rs8043757 in the first intron of the FTO gene are associated with increasing risk of obesity in Thais.
|
25542809 |
2015 |
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rs17817449
|
|
|
0.890 |
GeneticVariation |
BEFREE |
Numerous studies have demonstrated that the common variants (rs1421085 and rs17817449) of the fat mass and obesity associated (FTO) gene are associated with the obesity in adult and children in European.
|
24331679 |
2014 |
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rs17817449
|
|
|
0.890 |
GeneticVariation |
GWASDB |
For the binary trait of obesity, we found 16 genome-wide significant signals within the FTO gene (strongest signal at rs17817449, P = 2.5 × 10(-12)).
|
21552555 |
2011 |
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rs17817449
|
|
|
0.890 |
GeneticVariation |
BEFREE |
This study replicated the genetic association of SNP of FTO (rs17817449) with obesity in a north Indian population and, to the authors' knowledge; this is the first such association study in a north Indian population.
|
21919686 |
2011 |
|
rs17817449
|
|
|
0.890 |
GeneticVariation |
GWASCAT |
For the binary trait of obesity, we found 16 genome-wide significant signals within the FTO gene (strongest signal at rs17817449, P = 2.5 × 10(-12)).
|
21552555 |
2011 |
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rs17817449
|
|
|
0.890 |
GeneticVariation |
BEFREE |
Significant associations were detected between obesity risk and the five polymorphisms: rs9939609 (OR: 1.31, 95% CI: 1.26 to 1.36), rs1421085 (OR: 1.43, 95% CI: 1.33 to 1.53), rs8050136 (OR: 1.25, 95% CI: 1.13 to 1.38), rs17817449 (OR: 1.54, 95% CI: 1.41 to 1.68), and rs1121980 (OR: 1.34, 95% CI: 1.10 to 1.62).
|
21651756 |
2011 |
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rs17817449
|
|
|
0.890 |
GeneticVariation |
GWASDB |
Genome-wide population-based association study of extremely overweight young adults--the GOYA study.
|
21935397 |
2011 |
|
rs17817449
|
|
|
0.890 |
GeneticVariation |
BEFREE |
For the binary trait of obesity, we found 16 genome-wide significant signals within the FTO gene (strongest signal at rs17817449, P = 2.5 × 10(-12)).
|
21552555 |
2011 |
|
rs17817449
|
|
|
0.890 |
GeneticVariation |
BEFREE |
To widen the geographical coverage of the FTO studies, we have analyzed the association between the FTO gene variant rs17817449 (G>C) and obesity in a Slavic Eastern European population.
|
18833210 |
2008 |
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rs17817449
|
|
|
0.890 |
GeneticVariation |
BEFREE |
In European populations, common variants (rs1421085-C, rs17817449-G, and rs9939609-A) in the fat mass and obesity (FTO associated) were recently found to be associated with body mass index (BMI) or obesity.
|
17928949 |
2007 |