DisGeNET - a database of gene-disease associations

Obsessive-Compulsive Disorder, C0028768

Variant: rs25532 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs25532

SLC6A4 ; LOC105371720

0.030

GeneticVariation

BEFREE

There was no association between rs25532 or rs16965628 and OCD.

29102815

2018

dbSNP:

rs25532

SLC6A4 ; LOC105371720

0.030

GeneticVariation

BEFREE

Likewise, the higher expressing LAC haplotype (5-HTTLPR/rs25531/rs25532) was more frequent in TD probands than in controls (P = 0.024; OR, 1.33) and also in the TD alone group versus the TD plus OCD group (P = 0.0013; OR, 2.14).

23630162

2013

dbSNP:

rs25532

SLC6A4 ; LOC105371720

0.030

GeneticVariation

BEFREE

Haplotype-based testing of rs25532 and all other known non-coding functional SLC6A4 variants revealed a highly significant omnibus association with OCD in a large case-control sample.

18055562

2008