DisGeNET - a database of gene-disease associations

Pain, C0030193

Variant: rs6269 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs6269

COMT ; MIR4761

0.030

GeneticVariation

BEFREE

Pressure pain was significantly associated with rs6269 and rs4633 following butorphanol.

31806881

2019

dbSNP:

rs6269

COMT ; MIR4761

0.030

GeneticVariation

BEFREE

AA genotype of rs165774 could be a significant risk factor for the development of TMD and TMD pain, while AA genotype of rs6269 presents less postoperative chronic TMD pain and acute pain at a dental extraction site.

27792797

2017

dbSNP:

rs6269

COMT ; MIR4761

0.030

GeneticVariation

BEFREE

This study was aimed at the evaluation of the relationship between genetic polymorphisms of catechol-O-methyltransferase (COMT) (rs4680:A > G-Val158Met, rs6269:A > G, rs4633:C > T, rs4818:C > G) and pain sensitivity after lumbar discectomy.

24178190

2014