Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs113993959
rs113993959
T 0.700 CausalMutation CLINVAR

dbSNP: rs74597325
rs74597325
T 0.700 CausalMutation CLINVAR

dbSNP: rs1800629
rs1800629
TNF
0.010 GeneticVariation BEFREE We genotyped the selected SNPs (rs16944, rs1052536, rs1059293, rs1136410, rs1143634, rs2069762, rs2236302, rs2387632, rs3212961, rs3734299, rs3803258, rs4962081, rs7234941, rs7243091, rs12957119, and rs1800629) in 344 PNET sporadic cases and 2,721 controls in the context of the PANcreatic Disease ReseArch (PANDoRA) consortium.<b>Results:</b> After correction for multiple testing, we did not observe any statistically significant association between the SNPs and PNET risk. 28765340

2017

dbSNP: rs10094872
rs10094872
0.010 GeneticVariation BEFREE This analysis, in combination with a two-staged replication in an additional 6,076 case and 7,555 control subjects from the PANcreatic Disease ReseArch (PANDoRA) and Pancreatic Cancer Case-Control (PanC4) Consortia uncovered 3 new pancreatic cancer risk signals marked by single nucleotide polymorphisms (SNPs) rs2816938 at chromosome 1q32.1 (per allele odds ratio (OR) = 1.20, P = 4.88x10 -15), rs10094872 at 8q24.21 (OR = 1.15, P = 3.22x10 -9) and rs35226131 at 5p15.33 (OR = 0.71, P = 1.70x10 -8). 27579533

2016

dbSNP: rs2816938
rs2816938
0.010 GeneticVariation BEFREE This analysis, in combination with a two-staged replication in an additional 6,076 case and 7,555 control subjects from the PANcreatic Disease ReseArch (PANDoRA) and Pancreatic Cancer Case-Control (PanC4) Consortia uncovered 3 new pancreatic cancer risk signals marked by single nucleotide polymorphisms (SNPs) rs2816938 at chromosome 1q32.1 (per allele odds ratio (OR) = 1.20, P = 4.88x10 -15), rs10094872 at 8q24.21 (OR = 1.15, P = 3.22x10 -9) and rs35226131 at 5p15.33 (OR = 0.71, P = 1.70x10 -8). 27579533

2016

dbSNP: rs35226131
rs35226131
0.010 GeneticVariation BEFREE This analysis, in combination with a two-staged replication in an additional 6,076 case and 7,555 control subjects from the PANcreatic Disease ReseArch (PANDoRA) and Pancreatic Cancer Case-Control (PanC4) Consortia uncovered 3 new pancreatic cancer risk signals marked by single nucleotide polymorphisms (SNPs) rs2816938 at chromosome 1q32.1 (per allele odds ratio (OR) = 1.20, P = 4.88x10 -15), rs10094872 at 8q24.21 (OR = 1.15, P = 3.22x10 -9) and rs35226131 at 5p15.33 (OR = 0.71, P = 1.70x10 -8). 27579533

2016

dbSNP: rs1051740
rs1051740
0.010 GeneticVariation BEFREE The role of epoxide hydrolase Y113H gene variant in pancreatic diseases. 19287329

2009

dbSNP: rs1799945
rs1799945
0.010 GeneticVariation BEFREE Heterozygosity of p.C282Y and p.H63D may increase susceptibility to chronic liver and pancreatic disease. 17666895

2007

dbSNP: rs1800562
rs1800562
0.010 GeneticVariation BEFREE Heterozygosity of p.C282Y and p.H63D may increase susceptibility to chronic liver and pancreatic disease. 17666895

2007

dbSNP: rs17107315
rs17107315
0.010 GeneticVariation BEFREE In Bangladesh, the SPINK1 N34S mutation increases the risk of several forms of pancreatic disease, including fibrocalculous pancreatic diabetes, tropical calcific pancreatitis, and non-insulin-dependent diabetes mellitus. 12360464

2002

dbSNP: rs77010898
rs77010898
0.010 GeneticVariation BEFREE Cystic fibrosis (CF) patients bearing the premature translation termination mutation (nonsense mutation) W1282X present severe pulmonary and pancreatic disease, whereas patients carrying other nonsense mutations such as G542X, R553X, S1255X, R1162X, and W1316X show a severe pancreatic but mild pulmonary illness. 7504691

1993