Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10273639
rs10273639
PRSS1
0.820 GeneticVariation BEFREE Effects of PRSS1-PRSS2 rs10273639, CLDN2 rs7057398 and MORC4 rs12688220 polymorphisms on individual susceptibility to pancreatitis: A meta-analysis. 31163246

2020
dbSNP: rs10273639
rs10273639
PRSS1
0.820 GeneticVariation BEFREE While rs62228256 was not validated as a risk factor (<i>P</i>=0.77), both rs13228878 (<i>P</i>=0.03) and rs10273639 (<i>P</i>=0.04) were. rs13228878 and rs10273639 are in high linkage disequilibrium (r<sup>2</sup>=0.94) and associated with elevated expression of the <i>PRSS1</i> gene, which encodes for trypsinogen, and are known risk variants for alcohol-associated and sporadic pancreatitis in adults. 30467200

2019
dbSNP: rs10273639
rs10273639
PRSS1
C 0.820 GeneticVariation GWASCAT Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. 23143602

2012
dbSNP: rs10273639
rs10273639
PRSS1
C 0.820 GeneticVariation GWASDB Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. 23143602

2012
dbSNP: rs12688220
rs12688220
MORC4
0.810 GeneticVariation BEFREE Effects of PRSS1-PRSS2 rs10273639, CLDN2 rs7057398 and MORC4 rs12688220 polymorphisms on individual susceptibility to pancreatitis: A meta-analysis. 31163246

2020
dbSNP: rs12688220
rs12688220
MORC4
T 0.810 GeneticVariation GWASCAT Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. 23143602

2012
dbSNP: rs12688220
rs12688220
MORC4
T 0.810 GeneticVariation GWASDB Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. 23143602

2012
dbSNP: rs2995271
rs2995271
LOC101929279
T 0.800 GeneticVariation GWASDB Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. 23143602

2012
dbSNP: rs2995271
rs2995271
LOC101929279
T 0.800 GeneticVariation GWASCAT Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. 23143602

2012
dbSNP: rs379742
rs379742 		T 0.800 GeneticVariation GWASCAT Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. 23143602

2012
dbSNP: rs379742
rs379742 		T 0.800 GeneticVariation GWASDB Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. 23143602

2012
dbSNP: rs7057398
rs7057398
CLDN2 ; MORC4 ; RIPPLY1
0.710 GeneticVariation BEFREE Effects of PRSS1-PRSS2 rs10273639, CLDN2 rs7057398 and MORC4 rs12688220 polymorphisms on individual susceptibility to pancreatitis: A meta-analysis. 31163246

2020
dbSNP: rs7057398
rs7057398
CLDN2 ; MORC4 ; RIPPLY1
0.710 GeneticVariation GWASDB Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. 23143602

2012
dbSNP: rs4437130
rs4437130 		0.700 GeneticVariation GWASCAT NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. 29923122

2018
dbSNP: rs62561366
rs62561366 		0.700 GeneticVariation GWASCAT NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. 29923122

2018
dbSNP: rs12008279
rs12008279
CLDN2 ; MORC4
0.700 GeneticVariation GWASDB Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. 23143602

2012
dbSNP: rs12014762
rs12014762
MORC4
0.700 GeneticVariation GWASDB Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. 23143602

2012
dbSNP: rs4409525
rs4409525
MORC4
0.700 GeneticVariation GWASDB Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. 23143602

2012
dbSNP: rs5917027
rs5917027
CLDN2 ; MORC4
0.700 GeneticVariation GWASDB Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. 23143602

2012
dbSNP: rs6622126
rs6622126
MORC4
0.700 GeneticVariation GWASDB Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. 23143602

2012
dbSNP: rs201893408
rs201893408
TMEM67
C 0.700 GeneticVariation CLINVAR

dbSNP: rs74571530
rs74571530
CFTR ; CFTR-AS1
G 0.700 CausalMutation CLINVAR

dbSNP: rs752362727
rs752362727
TMEM67
T 0.700 GeneticVariation CLINVAR

dbSNP: rs886037774
rs886037774
LPL
C 0.700 GeneticVariation CLINVAR

dbSNP: rs886037775
rs886037775
LPL
T 0.700 GeneticVariation CLINVAR