rs823128
|
|
A |
0.850 |
GeneticVariation |
GWASCAT |
We replicated the effect of a new locus detected in the Japanese cohort (PARK16, rs823128, OR = 0.66, P = 7.29 x 10(-8)) and provide supporting evidence that common variation around LRRK2 modulates risk for PD (rs1491923, OR = 1.14, P = 1.55 x 10(-5)).
|
19915575 |
2009 |
rs823128
|
|
C |
0.850 |
GeneticVariation |
GWASDB |
We replicated the effect of a new locus detected in the Japanese cohort (PARK16, rs823128, OR = 0.66, P = 7.29 x 10(-8)) and provide supporting evidence that common variation around LRRK2 modulates risk for PD (rs1491923, OR = 1.14, P = 1.55 x 10(-5)).
|
19915575 |
2009 |
rs823128
|
|
|
0.850 |
GeneticVariation |
BEFREE |
We replicated the effect of a new locus detected in the Japanese cohort (PARK16, rs823128, OR = 0.66, P = 7.29 x 10(-8)) and provide supporting evidence that common variation around LRRK2 modulates risk for PD (rs1491923, OR = 1.14, P = 1.55 x 10(-5)).
|
19915575 |
2009 |
rs823128
|
|
|
0.850 |
GeneticVariation |
GWASDB |
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.
|
22438815 |
2012 |
rs823128
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Our results show that minor allele frequencies of rs11248051 (odds ratio [OR] 1.522; p=0.016) and rs3129882 (OR 1.294; p=0.03), but not rs823128 and rs947211, were associated with risk for PD.
|
24373818 |
2014 |
rs823128
|
|
|
0.850 |
GeneticVariation |
BEFREE |
The associations between rs823128/rs823156/rs708730 and PD are more likely to be replicated in Chinese and Malay populations.
|
25758099 |
2015 |
rs823128
|
|
|
0.850 |
GeneticVariation |
BEFREE |
The additive interaction between SNP rs823128 and smoking affecting sporadic PD was significant, although the multiplicative interaction was not significant.
|
26944116 |
2016 |
rs823128
|
|
|
0.850 |
GeneticVariation |
BEFREE |
In the combined analysis, results showed a significant association between rs823128 and PD in allelic model(G vs. A: OR=0.886, 95% CI=0.811-0.969, P=0.008), dominant model (GG+ AG vs. AA: OR=0.886, 95% CI=0.804-0.976, P=0.014), and heterozygote model (AG vs. AA: OR=0.897, 95% CI=0.812-0.991, P=0.032).
|
29191693 |
2018 |