DisGeNET - a database of gene-disease associations

Parkinson Disease, C0030567

Gene: SNCA ×

Source: GWASDB ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs3857059

SNCA

0.710

GeneticVariation

GWASDB

Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.

21738487

2011

dbSNP:

rs356168

SNCA

0.710

GeneticVariation

GWASDB

Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease.

20711177

2010

dbSNP:

rs3775439

SNCA

0.710

GeneticVariation

GWASDB

Genome-wide association study reveals genetic risk underlying Parkinson's disease.

19915575

2009

dbSNP:

rs3857059

SNCA

0.710

GeneticVariation

GWASDB

Genome-wide association study reveals genetic risk underlying Parkinson's disease.

19915575

2009

dbSNP:

rs2583988

SNCA ; SNCA-AS1

0.720

GeneticVariation

GWASDB

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.

22438815

2012

dbSNP:

rs2737029

SNCA

0.720

GeneticVariation

GWASDB

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.

22438815

2012

dbSNP:

rs894278

SNCA

0.720

GeneticVariation

GWASDB

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.

22438815

2012

dbSNP:

rs2737029

SNCA

0.720

GeneticVariation

GWASDB

Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.

21738487

2011

dbSNP:

rs894278

SNCA

0.720

GeneticVariation

GWASDB

Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.

21738487

2011

dbSNP:

rs894278

SNCA

0.720

GeneticVariation

GWASDB

Genome-wide association study reveals genetic risk underlying Parkinson's disease.

19915575

2009

dbSNP:

rs3822086

SNCA

0.730

GeneticVariation

GWASDB

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.

22438815

2012

dbSNP:

rs3822086

SNCA

0.730

GeneticVariation

GWASDB

Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.

21738487

2011

dbSNP:

rs7684318

SNCA

0.730

GeneticVariation

GWASDB

Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.

21738487

2011

dbSNP:

rs356165

SNCA

0.780

GeneticVariation

GWASDB

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.

22438815

2012

dbSNP:

rs356165

SNCA

0.780

GeneticVariation

GWASDB

Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.

21738487

2011

dbSNP:

rs356203

SNCA

0.800

GeneticVariation

GWASDB

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.

22438815

2012

dbSNP:

rs356203

SNCA

0.800

GeneticVariation

GWASDB

Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.

21738487

2011

dbSNP:

rs356220

SNCA ; LOC105377329

0.850

GeneticVariation

GWASDB

SNCA_ rs356220 was associated with both Sporadic-PD (OR = 1.37, P = 1 × 10(-9)) and Familial-PD (OR = 1.40, P = 2 × 10(-5)).

24511991

2014

dbSNP:

rs356220

SNCA ; LOC105377329

0.850

GeneticVariation

GWASDB

Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2.

22451204

2012

dbSNP:

rs356220

SNCA ; LOC105377329

0.850

GeneticVariation

GWASDB

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.

22438815

2012

dbSNP:

rs356220

SNCA ; LOC105377329

0.850

GeneticVariation

GWASDB

Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21.

21044948

2011

dbSNP:

rs356220

SNCA ; LOC105377329

0.850

GeneticVariation

GWASDB

Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population.

21084426

2011

dbSNP:

rs356220

SNCA ; LOC105377329

0.850

GeneticVariation

GWASDB

Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.

21738487

2011

dbSNP:

rs356220

SNCA ; LOC105377329

0.850

GeneticVariation

GWASDB

Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease.

20711177

2010

dbSNP:

rs2736990

SNCA

0.860

GeneticVariation

GWASDB

Identification of a novel Parkinson's disease locus via stratified genome-wide association study.

24511991

2014