| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.830 | GeneticVariation | BEFREE | In the meta-analysis study no loci reached a genome-wide significance level (P<5xE-8), but a suggestive association (P-value = 1.04E-6) between rs6430538 (ACMSD/TMEM163) and an increased risk of PD was found. | 31430546 | 2019 |
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|
0.830 | GeneticVariation | BEFREE | Herein, we investigated the effect of top three PD-associated genetic variants related to amino acid catabolism in Caucasians listed on the top risk loci identified by meta-analysis of genome-wide association studies in PDGene database, including aminocarboxymuconate-semialdehyde decarboxylase- (<i>ACMSD-</i>) transmembrane protein 163 (<i>TMEM163</i>) rs6430538, methylcrotonyl-CoA carboxylase 1 (<i>MCCC1</i>) rs12637471, and branched-chain ketoacid dehydrogenase kinase- (<i>BCKDK-</i>) syntaxin 1B (<i>STX1B</i>) rs14235, by genotyping 599 Taiwanese patients with PD and 598 age-matched control subjects. | 30719275 | 2019 |
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|
0.830 | GeneticVariation | BEFREE | Our study is the first to demonstrate that ACMSD/TMEM163 rs6430538, GPNMB rs199347 and BCKDK /STX1B rs14235 do not confer a significant risk for sporadic PD in mainland China. | 30880162 | 2019 |
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|
C | 0.830 | GeneticVariation | GWASCAT | A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci. | 28892059 | 2017 |
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C | 0.830 | GeneticVariation | GWASCAT | Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. | 25064009 | 2014 |
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|
0.830 | GeneticVariation | GWASCAT | Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2. | 22451204 | 2012 |
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0.830 | GeneticVariation | GWASDB | Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2. | 22451204 | 2012 |