Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.080 | GeneticVariation | BEFREE | No variant for either rs75932628 or rs2234253 was found in both PD and control cohorts. | 26704436 | 2016 |
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0.080 | GeneticVariation | BEFREE | Neither the entire PD nor the small PDD sample was associated with p.R47H. | 26651418 | 2016 |
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0.080 | GeneticVariation | BEFREE | Our results corroborate and extend previous findings, concluding that the variant rs75932628-T (p.R47H) in TREM2 is not a risk factor for LA or PD in the Han Chinese population. | 26758262 | 2016 |
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0.080 | GeneticVariation | BEFREE | We identified a significant association between rs75932628 and PD (P = 3.10E-03, odds ratio (OR) = 3.88, 95 % confidence interval (CI) 1.58-9.54) in No-Northern Europe subgroup, and significantly increased PD risks (P = 0.01 for Mann-Whitney test) in No-Northern Europe subgroup than in Northern Europe subgroup. | 26365049 | 2016 |
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0.080 | GeneticVariation | BEFREE | Assessment of TREM2 rs75932628 association with Parkinson's disease and multiple system atrophy in a Chinese population. | 26058955 | 2015 |
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0.080 | GeneticVariation | BEFREE | The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease. | 25936935 | 2015 |
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0.080 | GeneticVariation | BEFREE | Rs75932628-T (p.R47H) was found in 0.2% of PD cases (1/476) but in none of the controls (0/432, p = 1.000), with a minor allele frequency of 0.06% among the 908 subjects. | 24602511 | 2014 |
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0.080 | GeneticVariation | BEFREE | Our results suggest that the TREM2 p.R47H substitution is a risk factor for frontotemporal dementia and Parkinson's disease in addition to Alzheimer's disease. | 23800361 | 2013 |