|
rs1412005
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Subsequent analysis in nuclear families with childhood ADHD again showed an association of the promoter haplotype block (p=0.02). rs1412005 also increased risk toward BD (p=0.026) and cluster B PD (p=0.031).
|
21750579 |
2011 |
|
rs4570625
|
|
|
0.010 |
GeneticVariation |
BEFREE |
By doing so, we observed nominal evidence for G x E effects as well as main effects of 5-HTT-LPR and the TPH2 SNP rs4570625 on the occurrence of personality disorders.
|
19894072 |
2010 |
|
rs6295
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Only the G allele of HTR1A rs6295 seemed to increase the risk of emotional-dramatic cluster B personality disorders (p = 0.019, in the personality disorder sample) and to decrease the risk of anxious-fearful cluster C personality disorders (p = 0.016, in the aADHD sample).
|
19894072 |
2010 |
|
rs6265
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The low activity variants of the 5-HTT-linked polymorphic region in the serotonin transporter gene and the Met-allele of a single nucleotide polymorphism (Val66Met) in the gene encoding brain derived neurotrophic factor were independently associated with the presence of stressful life events prior to onset of depression, also when corrected for the effect of age, gender, marital status, personality disorder, neuroticism, and severity of depressive symptoms at the time of interview.
|
19339052 |
2009 |
|
rs759834365
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The low activity variants of the 5-HTT-linked polymorphic region in the serotonin transporter gene and the Met-allele of a single nucleotide polymorphism (Val66Met) in the gene encoding brain derived neurotrophic factor were independently associated with the presence of stressful life events prior to onset of depression, also when corrected for the effect of age, gender, marital status, personality disorder, neuroticism, and severity of depressive symptoms at the time of interview.
|
19339052 |
2009 |
|
rs776943620
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The low activity variants of the 5-HTT-linked polymorphic region in the serotonin transporter gene and the Met-allele of a single nucleotide polymorphism (Val66Met) in the gene encoding brain derived neurotrophic factor were independently associated with the presence of stressful life events prior to onset of depression, also when corrected for the effect of age, gender, marital status, personality disorder, neuroticism, and severity of depressive symptoms at the time of interview.
|
19339052 |
2009 |
|
rs6280
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Gly9,Gly9 genotype of the DRD3 Ser9Gly polymorphism was associated with increased rates of obsessive personality disorder symptomatology.
|
12860355 |
2003 |
|
rs6296
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There exists preliminary evidence for association of G861C with i) antisocial alcoholism in the Finnish; ii) alcoholism in the presence of inactive aldehyde dehydrogenase 2 in the Japanese; iii) a history of suicide attempts in European-American personality disorder patients; and iv) minimum lifetime body mass index in Canadian bulimia nervosa patients.
|
12437478 |
2002 |