Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs138996609
rs138996609
A 0.800 CausalMutation CLINVAR Superiority of [68Ga]-DOTATATE PET/CT to Other Functional Imaging Modalities in the Localization of SDHB-Associated Metastatic Pheochromocytoma and Paraganglioma. 25873086

2015

dbSNP: rs138996609
rs138996609
0.800 GeneticVariation UNIPROT Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline. 24893135

2014

dbSNP: rs138996609
rs138996609
0.800 GeneticVariation UNIPROT American Society of Clinical Oncology Expert Statement: collection and use of a cancer family history for oncology providers. 24493721

2014

dbSNP: rs138996609
rs138996609
A 0.800 CausalMutation CLINVAR Role of rapid sequence whole-body MRI screening in SDH-associated hereditary paraganglioma families. 23934599

2014

dbSNP: rs138996609
rs138996609
0.800 GeneticVariation UNIPROT Canadian guideline on genetic screening for hereditary renal cell cancers. 24319509

2013

dbSNP: rs138996609
rs138996609
A 0.800 CausalMutation CLINVAR Missense mutations in the human SDHB gene increase protein degradation without altering intrinsic enzymatic function. 22835832

2012

dbSNP: rs138996609
rs138996609
A 0.800 CausalMutation CLINVAR Screening of mutations in genes that predispose to hereditary paragangliomas and pheochromocytomas. 22517554

2012

dbSNP: rs138996609
rs138996609
A 0.800 CausalMutation CLINVAR Relevance of germline mutation screening in both familial and sporadic head and neck paraganglioma for early diagnosis and clinical management. 20208144

2010

dbSNP: rs138996609
rs138996609
A 0.800 CausalMutation CLINVAR The succinate dehydrogenase genetic testing in a large prospective series of patients with paragangliomas. 19454582

2009

dbSNP: rs138996609
rs138996609
A 0.800 CausalMutation CLINVAR Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out. 19351833

2009

dbSNP: rs138996609
rs138996609
A 0.800 CausalMutation CLINVAR Germline SDHB mutations are common in patients with apparently sporadic sympathetic paragangliomas. 18382370

2008

dbSNP: rs138996609
rs138996609
A 0.800 CausalMutation CLINVAR Succinate dehydrogenase B gene mutations predict survival in patients with malignant pheochromocytomas or paragangliomas. 17652212

2007

dbSNP: rs138996609
rs138996609
0.800 GeneticVariation UNIPROT Somatic SDHB mutation in an extraadrenal pheochromocytoma. 17634472

2007

dbSNP: rs138996609
rs138996609
0.800 GeneticVariation UNIPROT Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations. 15328326

2004

dbSNP: rs138996609
rs138996609
0.800 GeneticVariation UNIPROT Novel succinate dehydrogenase subunit B (SDHB) mutations in familial phaeochromocytomas and paragangliomas, but an absence of somatic SDHB mutations in sporadic phaeochromocytomas. 12618761

2003

dbSNP: rs138996609
rs138996609
A 0.800 CausalMutation CLINVAR Mutations in the SDHB gene are associated with extra-adrenal and/or malignant phaeochromocytomas. 14500403

2003

dbSNP: rs138996609
rs138996609
0.800 GeneticVariation UNIPROT Mutations in the SDHB gene are associated with extra-adrenal and/or malignant phaeochromocytomas. 14500403

2003

dbSNP: rs138996609
rs138996609
0.800 GeneticVariation UNIPROT Genetic analysis of mitochondrial complex II subunits SDHD, SDHB and SDHC in paraganglioma and phaeochromocytoma susceptibility. 14974914

2003

dbSNP: rs138996609
rs138996609
0.800 GeneticVariation UNIPROT Germ-line mutations in nonsyndromic pheochromocytoma. 12000816

2002

dbSNP: rs138996609
rs138996609
0.800 GeneticVariation UNIPROT Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma. 11404820

2001